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We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference…

Medical Physics · Physics 2018-07-12 F. Troiani , K. Nikolic , T. G. Constandinou

Purpose: Microaneurysms (MAs) have distinct, oval-shaped, hyperreflective walls on structural OCT, and inconsistent flow signal in the lumen with OCT angiography (OCTA). Their relationship to regional macular edema in diabetic retinopathy…

Quantitative Methods · Quantitative Biology 2023-10-11 Min Gao , Tristan T. Hormel , Yukun Guo , Kotaro Tsuboi , Christina J. Flaxel , David Huang , Thomas S. Hwang , Yali Jia

Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

Real-time high-accuracy optical flow estimation is critical for a variety of real-world robotic applications. However, current learning-based methods often struggle to balance accuracy and computational efficiency: methods that achieve high…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Zhiyong Zhang , Aniket Gupta , Huaizu Jiang , Hanumant Singh

Event cameras respond to changes in log-brightness at the millisecond level, making them ideal for optical flow estimation. However, existing datasets from event cameras provide only low frame rate ground truth for optical flow, limiting…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Yaozu Ye , Hao Shi , Kailun Yang , Ze Wang , Xiaoting Yin , Lei Sun , Yaonan Wang , Kaiwei Wang

This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Bilal Hassan , Taimur Hassan , Ramsha Ahmed , Shiyin Qin , Naoufel Werghi

Intrinsic optical signal (IOS) imaging of the retina, also termed as optoretinography (ORG), promises a noninvasive method for objective assessment of retinal function. By providing unparalleled capability to differentiate individual layers…

Medical Physics · Physics 2022-02-22 Tae-Hoon Kim , Guangying Ma , Taeyoon Son , Xincheng Yao

Doppler holography is an emerging retinal imaging technique that captures the dynamic behavior of blood flow with high temporal resolution, enabling quantitative assessment of retinal hemodynamics. This requires accurate segmentation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Marius Dubosc , Yann Fischer , Zacharie Auray , Nicolas Boutry , Edwin Carlinet , Michael Atlan , Thierry Geraud

The variation of blood flow characteristics caused by the probe pressure during noninvasive studies is of particular interest within the context of fundamental and applied research. It has been shown previously that the weak local pressure…

The lack of efficient segmentation methods and fully-labeled datasets limits the comprehensive assessment of optical coherence tomography angiography (OCTA) microstructures like retinal vessel network (RVN) and foveal avascular zone (FAZ),…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Peng Xiao , Xiaodong Hu , Ke Ma , Gengyuan Wang , Ziqing Feng , Yuancong Huang , Jin Yuan

Optical flow is a classical task that is important to the vision community. Classical optical flow estimation uses two frames as input, whilst some recent methods consider multiple frames to explicitly model long-range information. The…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qiaole Dong , Yanwei Fu

Defining vascular age in terms of physiological function has become one focal point of the extensive studies to categorize and track chronological age. Transcranial Doppler (TCD) is a method by which cerebral blood flow velocity is measured…

Artificial Intelligence · Computer Science 2026-05-19 Anni Zhao , Alex Bateh , Tyler Baldridge , Sandra Billinger , Xiao Hu

Event cameras deliver visual information characterized by a high dynamic range and high temporal resolution, offering significant advantages in estimating optical flow for complex lighting conditions and fast-moving objects. Current…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Gangwei Xu , Haotong Lin , Zhaoxing Zhang , Hongcheng Luo , Haiyang Sun , Xin Yang

Temporal feature extraction is an important issue in video-based action recognition. Optical flow is a popular method to extract temporal feature, which produces excellent performance thanks to its capacity of capturing pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2020-05-07 Yuecong Xu , Jianfei Yang , Kezhi Mao , Jianxiong Yin , Simon See

In the domain of computer vision, optical flow stands as a cornerstone for unraveling dynamic visual scenes. However, the challenge of accurately estimating optical flow under conditions of large nonlinear motion patterns remains an open…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Chanuka Algama , Kasun Amarasinghe

Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Shir Gur , Lior Wolf , Lior Golgher , Pablo Blinder

Occlusions between consecutive frames have long posed a significant challenge in optical flow estimation. The inherent ambiguity introduced by occlusions directly violates the brightness constancy constraint and considerably hinders…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Shangkun Sun , Jiaming Liu , Thomas H. Li , Huaxia Li , Guoqing Liu , Wei Gao

Clinical tracking systems are popular but typically require specific tracking markers. During the last years, scanning speed of optical coherence tomography (OCT) has increased to A-scan rates above 1 MHz allowing to acquire volume scans of…

Medical Physics · Physics 2019-01-15 Matthias Schlüter , Christoph Otte , Thore Saathoff , Nils Gessert , Alexander Schlaefer

The purpose of this study is to evaluate the performance of the OphtAI system for the automatic detection of referable diabetic retinopathy (DR) and the automatic assessment of DR severity using color fundus photography. OphtAI relies on…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Gwenolé Quellec , Mathieu Lamard , Bruno Lay , Alexandre Le Guilcher , Ali Erginay , Béatrice Cochener , Pascale Massin

While the pathophysiology underlying the COVID-19 infection remains incompletely understood, there is growing evidence to indicate that it is closely correlated to hypercoagulation among severely ill patients. Doctors may choose for use…

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