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We present here a real-time analysis of diffraction images acquired at high frame-rate (925 Hz) and its application to macromolecular serial crystallography. The software uses a new signal separation algorithm, able to distinguish the…

Images acquired by computer vision systems under low light conditions have multiple characteristics like high noise, lousy illumination, reflectance, and bad contrast, which make object detection tasks difficult. Much work has been done to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-02 Winston Chen , Tejas Shah

In this paper, we presented an efficient algorithm to implement the regularization reconstruction of SPECT. Image reconstruction with priori assumptions is usually modeled as a constrained optimization problem. However, there is no…

Optimization and Control · Mathematics 2013-06-07 Shousheng Luo , Tie Zhou

Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method for biological macromolecules. Cryo-EM was selected by Nature Methods as Method of the…

Computational Physics · Physics 2018-03-20 Amit Singer

Deep neural networks have emerged as very successful tools for image restoration and reconstruction tasks. These networks are often trained end-to-end to directly reconstruct an image from a noisy or corrupted measurement of that image. To…

Image and Video Processing · Electrical Eng. & Systems 2021-06-30 Zalan Fabian , Reinhard Heckel , Mahdi Soltanolkotabi

Low-light image enhancement task is essential yet challenging as it is ill-posed intrinsically. Previous arts mainly focus on the low-light images captured in the visible spectrum using pixel-wise loss, which limits the capacity of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Shulin Tian , Yufei Wang , Renjie Wan , Wenhan Yang , Alex C. Kot , Bihan Wen

High-throughput 2D and 3D scanning electron microscopy, which relies on automation and dependable control algorithms, requires high image quality with minimal human intervention. Classical focus and astigmatism correction algorithms attempt…

Instrumentation and Detectors · Physics 2023-05-10 Philipp Johannes Schubert , Rangoli Saxena , Joergen Kornfeld

A small ISO and a small exposure time are usually used to capture an image in the back or low light conditions which results in an image with negligible motion blur and small noise but look dark. In this paper, a single image brightening…

Computer Vision and Pattern Recognition · Computer Science 2020-07-27 Chaobing Zheng , Zhengguo Li , Yi Yang , Shiqian Wu

Image reconstruction in the presence of severe degradation remains a challenging inverse problem, particularly in beam diagnostics for high-energy physics accelerators. As modern facilities demand precise detection of beam halo structures…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Francis Osswald , Mohammed Chahbaoui , Xinyi Liang

Visual generative AI models often encounter challenges related to text-image alignment and reasoning limitations. This paper presents a novel method for selectively enhancing the signal at critical denoising steps, optimizing image…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Paul Grimal , Hervé Le Borgne , Olivier Ferret

In this paper, we show how we can combine Electromagnetics (EM) with signal processing algorithms to enhance the image resolution over that can be realized by using Electromagnetics techniques alone. We discuss several signal processing…

Optics · Physics 2013-05-14 Xiang Gu , Chiara Pelletti , Raj Mittra , Yunhua Zhang

We introduce the EMC algorithm for reconstructing a particle's 3D diffraction intensity from very many photon shot-noise limited 2D measurements, when the particle orientation in each measurement is unknown. The algorithm combines a…

Data Analysis, Statistics and Probability · Physics 2010-03-04 Duane Ne-Te Loh , Veit Elser

Nowadays, due to advanced digital imaging technologies and internet accessibility to the public, the number of generated digital images has increased dramatically. Thus, the need for automatic image enhancement techniques is quite apparent.…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 Saeedeh Rezaee , Nezam Mahdavi-Amiri

High-resolution structure determination by cryo-electron microscopy (cryo-EM) requires the accurate fitting of an atomic model into an experimental density map. Traditional refinement pipelines such as Phenix.real_space_refine and Rosetta…

Biomolecules · Quantitative Biology 2026-03-10 Fuyao Huang , Xiaozhu Yu , Kui Xu , Qiangfeng Cliff Zhang

In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Fabio Hernán Gil Zuluaga , Francesco Bardozzo , Jorge Iván Ríos Patiño , Roberto Tagliaferri

Traditional metrics for evaluating the efficacy of image processing techniques do not lend themselves to understanding the capabilities and limitations of modern image processing methods - particularly those enabled by deep learning. When…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Chris M. Ward , Josh Harguess , Brendan Crabb , Shibin Parameswaran

We show that de-focused single particle images recorded using a cryo-electron microscope (cryoEM) system may be processed like a Fresnel zone in-line hologram to obtain physically meaningful quantitative phase maps associated with…

Image and Video Processing · Electrical Eng. & Systems 2021-11-24 Apoorv Pant , Manidipa Banerjee , Kedar Khare

In image enhancement tasks, such as low-light and underwater image enhancement, a degraded image can correspond to multiple plausible target images due to dynamic photography conditions. This naturally results in a one-to-many mapping…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Guoxi Huang , Qirui Yang , Ruirui Lin , Zipeng Qi , David Bull , Nantheera Anantrasirichai

Working from a Poisson-Gaussian noise model, a multi-sample extension of the Photon Counting Histogram Expectation Maximization (PCH-EM) algorithm is derived as a general-purpose alternative to the Photon Transfer (PT) method. This…

Instrumentation and Detectors · Physics 2024-03-08 Aaron J. Hendrickson , David P. Haefner , Stanley H. Chan , Nicholas R. Shade , Eric R. Fossum

In various Computer Vision and Signal Processing applications, noise is typically perceived as a drawback of the image capturing system that ought to be removed. We, on the other hand, claim that image noise, just as texture, is important…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Renata Khasanova , Jan Wassenberg , Jyrki Alakuijala