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In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

Analysis of PDEs · Mathematics 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang

During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

Populations and Evolution · Quantitative Biology 2021-04-28 Joseph Samuel , Supurna Sinha

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu

This paper presents a novel methodology to tackle feedback optimal control problems in scenarios where the exact state of the controlled process is unknown. It integrates data assimilation techniques and optimal control solvers to manage…

Optimization and Control · Mathematics 2024-04-10 Siming Liang , Ruoyu Hu , Feng Bao , Richard Archibald , Guannan Zhang

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

Populations and Evolution · Quantitative Biology 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

In this paper we investigate feedback control techniques for the COVID-19 pandemic which are able to guarantee that the capacity of available intensive care unit beds is not exceeded. The control signal models the social distancing policies…

Optimization and Control · Mathematics 2021-10-29 Thomas Berger

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

This paper considers a half-duplex scenario where an interferer behaves according to a parametric model but the values of the model parameters are unknown. We explore the necessary number of sensing steps to gather sufficient knowledge…

Information Theory · Computer Science 2024-10-11 Vincent Corlay , Jean-Christophe Sibel , Nicolas Gresset

Mathematical models are instrumental to forecast the spread of pathogens and to evaluate the effectiveness of non-pharmaceutical measures. A plethora of optimal strategies has been recently developed to minimize either the infected peak…

Dynamical Systems · Mathematics 2021-11-11 J. Sereno , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

In this paper, we address a social planner's optimal control problem for a partially observable stochastic epidemic model. The control measures include social distancing, testing, and vaccination. Using a diffusion approximation for the…

Optimization and Control · Mathematics 2025-03-11 Ibrahim Mbouandi Njiasse , Florent Ouabo Kamkumo , Ralf Wunderlich

We consider a susceptible-infected-susceptible (SIS) epidemic model in which a large group of individuals decide whether to adopt partially effective protection without being aware of their individual infection status. Each individual…

Systems and Control · Electrical Eng. & Systems 2024-10-29 Urmee Maitra , Ashish R. Hota , Philip E. Paré

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

Populations and Evolution · Quantitative Biology 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

We consider the effects of noise on a model of epidemic outbreaks, where the outbreaks appear. randomly. Using a constructive transition approach that predicts large outbreaks, prior to their occurrence, we derive an adaptive control.…

Chaotic Dynamics · Physics 2009-11-11 I. B. Schwartz , L. Billings , E. M. Bollt

Epidemic models are useful tools in the fight against infectious diseases, as they allow policy makers to test and compare various strategies to limit disease transmission while mitigating collateral damage on the economy. Epidemic models…

Populations and Evolution · Quantitative Biology 2021-08-18 Joseph D. Peterson , Ronojoy Adhikari

This study develops and analyzes an extended Susceptible, Infected, Hospitalized and Recovered (SIHR) model incorporating time dependent control functions to capture preventive measures (e.g., distancing, mask use) and resource limited…

Populations and Evolution · Quantitative Biology 2025-10-01 Liban Ismail , Yahyeh Souleiman , Saraless Nadarajah , Abdisalam Hassan

In this paper, we consider the problem of optimizing the worst-case behavior of a partially observed system. All uncontrolled disturbances are modeled as finite-valued uncertain variables. Using the theory of cost distributions, we present…

Optimization and Control · Mathematics 2023-02-21 Aditya Dave , Nishanth Venkatesh , Andreas A. Malikopoulos

A crucial aspect of managing a public health crisis is to effectively balance prevention and mitigation strategies, while taking their socio-economic impact into account. In particular, determining the influence of different…