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In robotic radiation therapy, high-energy photon beams from different directions are directed at a target within the patient. Target motion can be tracked by robotic ultrasound and then compensated by synchronous beam motion. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-03-29 Lars Beckers , Stefan Gerlach , Ole Lübke , Alexander Schlaefer , Sibylle Schupp

A fundamental model of tumor growth in the presence of cytotoxic chemotherapeutic agents is formulated. The model allows to study the role of the Norton-Simon hypothesis in the context of dose-dense chemotherapy. Dose-dense protocols aim at…

Populations and Evolution · Quantitative Biology 2018-12-05 Álvaro G. López , Kelly C. Iarosz , Antonio M. Batista , Jesús M. Seoane , Ricardo L. Viana , Miguel A. F. Sanjuán

Objective: We propose a semiautomatic pipeline for radiation therapy treatment planning, combining ideas from machine learning-automated planning and multicriteria optimization (MCO). Approach: Using knowledge extracted from historically…

Medical Physics · Physics 2022-02-16 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

The problem of multi-area interchange scheduling under system uncertainty is considered. A new scheduling technique is proposed for a multi-proxy bus system based on stochastic optimization that captures uncertainty in renewable generation…

Optimization and Control · Mathematics 2016-11-16 Yuting Ji , Lang Tong

Schedules can be built in a similar way to a human scheduler by using a set of rules that involve domain knowledge. This paper presents an Estimation of Distribution Algorithm (eda) for the nurse scheduling problem, which involves choosing…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Jingpeng Li

Staff scheduling is a universal problem that can be encountered in many organizations, such as call centers, educational institution, industry, hospital, and any other public services. It is one of the most important aspects of workforce…

Artificial Intelligence · Computer Science 2019-02-05 O. M. Alade , A. O. Amusat

Workforce scheduling in the healthcare sector is a significant operational challenge, characterized by fluctuating patient loads, diverse clinical skills, and the critical need to control labor costs while upholding high standards of…

Artificial Intelligence · Computer Science 2025-08-29 Vipul Patel , Anirudh Deodhar , Dagnachew Birru

While the use of combination therapy is increasing in prevalence for cancer treatment, it is often difficult to predict the exact interactions between different treatment forms, and their synergistic/antagonistic effects on patient health…

Optimization and Control · Mathematics 2021-01-29 Jayanth Pratap

We consider a distributed computing network consisting of a master and multiple workers processing tasks of different types. The master is running multiple applications. Each application stochastically generates real-time jobs with a strict…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-31 Yu-Pin Hsu , Yu-Chih Huang , Shin-Lin Shieh

We study the elective surgery planning problem in a hospital with operation rooms shared by elective and emergency patients. This problem can be split in two distinct phases. First, a subset of patients to be operated in the next planning…

Optimization and Control · Mathematics 2024-03-07 Mohammed Majthoub Almoghrabi , Guillaume Sagnol

Among the genetic algorithms generally used for optimization problems in the recent decades, quantum-inspired variants are known for fast and high-fitness convergence and small resource requirement. Here the application to the patient…

Neural and Evolutionary Computing · Computer Science 2025-06-06 Akira SaiToh , Arezoo Modiri , Amit Sawant , Robabeh Rahimi

A Bayesian optimization algorithm for the nurse scheduling problem is presented, which involves choosing a suitable scheduling rule from a set for each nurses assignment. Unlike our previous work that used Gas to implement implicit…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Jingpeng Li , Uwe Aickelin

Disease management programs have emerged as a cost-effective approach to treat chronic diseases. Appointment adherence is critical to the success of such programs; missed appointment are costly, resulting in reduced resource utilization and…

Optimization and Control · Mathematics 2015-05-29 Martin Savelsbergh , Karen Smilowitz

Inpatient care is a large share of total health care spending, making analysis of inpatient utilization patterns an important part of understanding what drives health care spending growth. Common features of inpatient utilization measures…

Machine Learning · Statistics 2017-11-22 Christoph Kurz , Laura Hatfield

Coflow provides a key application-layer abstraction for capturing communication patterns, enabling the efficient coordination of parallel data flows to reduce job completion times in distributed systems. Modern data center networks (DCNs)…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-10 Xin Wang , Hong Shen , Hui Tian , Dong Wang

This paper addresses the joint scheduling problem of stochastic workloads and a hydrogen-enabled distributed energy system in a low-carbon Internet data centers (IDC). Although such workloads can be shifted over temporal and spatial…

Systems and Control · Electrical Eng. & Systems 2025-12-05 Maoyuan Ma , Wangyi Guo , Lei Yang , Zhanbo Xu , Xiaohong Guan

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

The global home healthcare market is growing rapidly due to aging populations, advancements in healthcare technology, and patient preference for home-based care. In this paper, we study the multi-day planning problem of simultaneously…

Optimization and Control · Mathematics 2024-07-10 Carolin Bauerhenne , Jonathan Bard , Rainer Kolisch

In cancer treatment, chemotherapy is administered according a constant schedule. The chronotherapy approach, considering chronobiological drug delivery, adapts the chemotherapy profile to the circadian rhythms of the human organism. This…

Quantitative Methods · Quantitative Biology 2016-04-12 Benjamin Schott , Johannes Stegmaier , Alexandre Arbaud , Markus Reischl , Ralf Mikut , Francis Lévi

Limited English Proficiency (LEP) patients face higher risks of adverse health outcomes due to communication barriers, making timely medical interpreting services essential for mitigating those risks. This paper addresses the scheduling of…

Discrete Mathematics · Computer Science 2025-01-16 Abdulaziz Ahmed , Aida Jebali