English
Related papers

Related papers: Scheduling chemotherapy appointments under uncerta…

200 papers

Healthcare systems are facing serious challenges in balancing their human resources to cope with volatile service demand, while at the same time providing necessary job satisfaction to the healthcare workers. We propose in this paper a…

Optimization and Control · Mathematics 2021-03-09 Duy Anh Nguyen

The combination of cytotoxic therapies and anti-angiogenic agents is emerging as a most promising strategy in the treatment of malignant tumors. However, the timing and sequencing of these treatments seem to play essential roles in…

Tissues and Organs · Quantitative Biology 2011-06-13 M. Kohandel , C. A. Haselwandter , M. Kardar , S. Sengupta , S. Sivaloganathan

Dispatchability of renewable energy sources and inflexible loads can be achieved using a volatility-compensating energy storage. However, as the future power outputs of the inflexible devices are uncertain, the computation of a dispatch…

Systems and Control · Computer Science 2018-05-25 R. R. Appino , J. Á. González Ordiano , R. Mikut , V. Hagenmeyer , T. Faulwasser

This paper studies a sequential decision-making problem in a two-stage queueing system modeled after operations in CVS MinuteClinics, where nurse practitioners (NPs) oversee patient care throughout the entire visit. All services are…

Optimization and Control · Mathematics 2026-03-11 Shuwen Lu , Mark E. Lewis , Jamol Pender

The predicted increase in the number of patients receiving radiation therapy (RT) to treat cancer calls for an optimized use of resources. To manually schedule patients on the linear accelerators delivering RT is a time-consuming and…

Optimization and Control · Mathematics 2023-03-29 Sara Frimodig , Carole Mercier , Geert De Kerf

In this paper, we study a queueing model that incorporates patient reentrance to reflect patients' recurring requests for nurse care and their rest periods between these requests. Within this framework, we address two levels of…

Optimization and Control · Mathematics 2024-06-19 Wei Liu , Mengshi Lu , Pengyi Shi

Radiotherapy treatment planning is a challenging large-scale optimization problem plagued by uncertainty. Following the robust optimization methodology, we propose a novel, spatially based uncertainty set for robust modeling of radiotherapy…

Optimization and Control · Mathematics 2024-05-28 Noam Goldberg , Mark P. Langer , Shimrit Shtern

Appointment scheduling problems under uncertainty encounter a fundamental trade-off between cost minimization and customer waiting times. Most existing studies address this trade-off using a weighted sum approach, which puts little emphasis…

General Economics · Economics 2026-01-06 Carolin Bauerhenne , Rainer Kolisch , Andreas S. Schulz

Radiotherapy planning naturally leads to a multi-criteria optimization problem which is subject to different sources of uncertainty. In order to find the desired treatment plan, a decision maker must balance these objectives as well as the…

Optimization and Control · Mathematics 2026-01-27 Jan Schröeder , Yair Censor , Philipp Süss , Karl-Heinz Küfer

BACKGROUND: Analytical techniques are being implemented with increasing frequency to improve the management of surgical departments and to ensure that decisions are well-informed. Often these analytical techniques rely on the validity of…

Applications · Statistics 2018-09-25 Belinda Spratt , Erhan Kozan , Michael Sinnott

In recent years genetic algorithms have emerged as a useful tool for the heuristic solution of complex discrete optimisation problems. In particular there has been considerable interest in their use in tackling problems arising in the areas…

Artificial Intelligence · Computer Science 2010-07-05 Uwe Aickelin

Optimizing car sharing systems under demand uncertainty is an emerging problem for ensuring profitable and sustainable operations of these services while taking into account quality of service concerns. With the increasing adoption of…

Optimization and Control · Mathematics 2023-07-18 Sinan Emre Kosunda , Beste Basciftci , Esra Koca

Chemotherapy is one of the most important therapeutic options used to treat human cancers, either alone or in combination with radiation therapy and surgery. Recent studies have indicated that intra-tumoural heterogeneity has a significant…

Tissues and Organs · Quantitative Biology 2014-07-04 Gibin G Powathil , Mark AJ Chaplain , Maciej Swat

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…

We study a routing and appointment scheduling problem with uncertain service and travel times arising from home service practice. Specifically, given a set of customers within a service region that an operator needs to serve, we seek to…

Optimization and Control · Mathematics 2021-11-23 Man Yiu , Tsang , Karmel S. Shehadeh

We propose stochastic optimization methodologies for a staffing and capacity planning problem arising from home care practice. Specifically, we consider the perspective of a home care agency that must decide the number of caregivers to hire…

Optimization and Control · Mathematics 2022-03-29 Ridong Wang , Karmel S. Shehadeh , Xiaolei Xie , Lefei Li

We investigate computational and mechanism design aspects of scarce resource allocation, where the primary rationing mechanism is through waiting times. Specifically we consider allocating medical treatments to a population of patients.…

Computer Science and Game Theory · Computer Science 2013-12-09 Mark Braverman , Jing Chen , Sampath Kannan

The number of cancer cases per year is rapidly increasing worldwide. In radiation therapy (RT), radiation from linear accelerators is used to kill malignant tumor cells. Scheduling patients for RT is difficult both due to the numerous…

Optimization and Control · Mathematics 2023-03-21 Sara Frimodig , Per Enqvist , Jan Kronqvist

We study a single-server appointment scheduling problem with a fixed sequence of appointments, for which we must determine the arrival time for each appointment. We specifically examine two stochastic models. In the first model, we assume…

Optimization and Control · Mathematics 2019-07-09 Ruiwei Jiang , Minseok Ryu , Guanglin Xu