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We investigate the point spread function of a multimode fiber. The distortion of the focal spot created on the fiber output facet is studied for a variety of the parameters. We develop a theoretical model of wavefront shaping through a…

Optics · Physics 2018-05-18 Adrien Descloux , Lyubov V. Amitonova , Pepijn W. H. Pinkse

The importance of spin-correlated radical pairs in biology is increasingly recognized, with roles in biological effects of weak magnetic fields and emerging quantum spin-based biomedical applications. Fluorescence microscopy offers…

Biological Physics · Physics 2025-10-08 Noboru Ikeya , Jonathan R. Woodward

Single molecule localization microscopy relies on the precise quantification of the position of single dye emitters in a sample. This precision is improved by the number of photons that can be detected from each molecule. It is therefore…

Photonic Lanterns (PLs) are tapered waveguides that gradually transition from a multi-mode fiber geometry to a bundle of single-mode fibers (SMFs). They can efficiently couple multi-mode telescope light into a multi-mode fiber entrance at…

Instrumentation and Methods for Astrophysics · Physics 2024-02-14 Yoo Jung Kim , Michael P. Fitzgerald , Jonathan Lin , Steph Sallum , Yinzi Xin , Nemanja Jovanovic , Sergio Leon-Saval

Molecular fluorescence microscopy is a leading approach to super-resolution and nanoscale imaging in life and material sciences. However, super-resolution fluorescence microscopy is often bottlenecked by system-specific calibrations and…

In this study, we introduce a new approach to fabricating fiber optic microlenses using a three-electrode arc fusion splicer. Through beam propagation method-based simulations, we verified the performance of our lenses, achieving highly…

Optics · Physics 2024-12-02 Szymon Matczak , Dorota Stachowiak , Grzegorz Soboń

We study the Single File Diffusion (SFD) of a cyclic chain of particles that cannot cross each other, in a thermal bath, with long ranged interactions, and arbitrary damping. We present simulations that exhibit new behaviors specifically…

Statistical Mechanics · Physics 2015-05-27 Jean-Baptiste Delfau , Christophe Coste , Michel Saint-Jean

The interplay between the oxidation state and the optical properties of molecules plays a key role for applications in displays, sensors or molecular-based memories. The fundamental mechanisms occurring at the level of a single-molecule…

Mesoscale and Nanoscale Physics · Physics 2018-08-15 Benjamin Doppagne , Michael C. Chong , Hervé Bulou , Alex Boeglin , Fabrice Scheurer , Guillaume Schull

Aberrations and multiple scattering in biological tissues critically distort light beams into highly complex speckle patterns. In this regard, digital optical phase conjugation (DOPC) is a promising technique enabling in-depth focusing.…

Several matrix approaches were developed to control light propagation through multiple scattering media under illumination of ultrashort pulses of light. These matrices can be recorded either with spectral or temporal resolution. Thanks to…

Optics · Physics 2018-06-08 Mickael Mounaix , Duc Minh Ta , Sylvain Gigan

Fluorescent molecules emit light in a dipole radiation pattern that can be used to infer their orientation through defocused fluorescence microscopy. Proper measurement of the orientation requires mathematical modeling of the radiation…

Optics · Physics 2025-08-07 E. Dey , M. Elorza , F. W. Foss , J. J. Gomez Cadenas , B. J. P. Jones

Ground based optical telescopes are seriously affected by atmospheric turbulence induced aberrations. Understanding properties of these aberrations is important both for instruments design and image restoration methods development. Because…

Instrumentation and Methods for Astrophysics · Physics 2020-04-08 Peng Jia , Xuebo Wu , Yi Huang , Bojun Cai , Dongmei Cai

Elemental mapping images can be achieved through step scanning imaging using pinhole optics or micro pore optics (MPO), or alternatively by full-field X-ray fluorescence imaging (FF-XRF). X-ray optics for FF-XRF can be manufactured with…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Siwen An , David Krapohl , Benny Thörnberg , Romain Roudot , Emile Schyns , Börje Norlin

A single-biomolecule optical toggle-switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor GFP molecular structure and photophysical properties and give it…

The accurate modelling of the Point Spread Function (PSF) is of paramount importance in astronomical observations, as it allows for the correction of distortions and blurring caused by the telescope and atmosphere. PSF modelling is crucial…

Instrumentation and Methods for Astrophysics · Physics 2023-09-25 Tobias Liaudat , Jean-Luc Starck , Martin Kilbinger

In this article, we address fluorescence of single molecule inside a plasmonic picocavity by proposing a semi-classical theory via combining the macroscopic quantum electrodynamics theory and the open quantum system theory. To gain insights…

Mesoscale and Nanoscale Physics · Physics 2021-12-20 Siyuan Lyu , Yuan Zhang , Yao Zhang , Kainan Chang , Guangchao Zheng , Luxia Wang

Fluorescence microscopy is of vital importance for understanding biological function. However most fluorescence experiments are only qualitative inasmuch as the absolute number of fluorescent particles can often not be determined.…

Current Flash X-ray single-particle diffraction Imaging (FXI) experiments, which operate on modern X-ray Free Electron Lasers (XFELs), can record millions of interpretable diffraction patterns from individual biomolecules per day. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-02-20 Jing Liu , Gijs van der Schot , Stefan Engblom

We propose and demonstrate a novel technique that combines Raman scattering and optical cycling in molecules with diagonal Franck-Condon factors. This resonance Raman optical cycling manipulates molecules to behave like efficient…

Atomic Physics · Physics 2021-08-26 J. C. Shaw , J. C. Schnaubelt , D. J. McCarron

Color centers in diamond nanocrystals are a new class of fluorescence markers that attract significant interest due to matchless brightness, photostability and biochemical inertness. Fluorescing diamond nanocrystals containing defects can…

Biomolecules · Quantitative Biology 2009-11-13 M. Boersch , R. Reuter , G. Balasubramanian , R. Erdmann , F. Jelezko , J. Wrachtrup
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