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This paper presents a new view of household epidemic models, where the interaction between the households is of mean field type. We thus obtain in the limit of infinitely many households a nonlinear Markov process solution of a McKean -…

Probability · Mathematics 2022-10-04 Raphael Forien , Etienne Pardoux

For a heterogeneous host population, the basic reproduction number of an infectious disease, $\cR_0$, is defined as the spectral radius of the next generation operator (NGO). The threshold properties of the basic reproduction number are…

Populations and Evolution · Quantitative Biology 2025-04-29 Horst R Thieme

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

Epidemic dynamics in a stochastic network of interacting epidemic centers is considered. The epidemic and migration processes are modelled by Markov's chains. Explicit formulas for probability distribution of the migration process are…

Populations and Evolution · Quantitative Biology 2015-05-05 Igor Sazonov , Mark Kelbert

We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

Populations and Evolution · Quantitative Biology 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

Populations and Evolution · Quantitative Biology 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

Reproduction numbers, like the basic reproduction number $\mathcal{R}_0$, play an important role in the analysis and application of dynamic models, including contagion models and ecological population models. One difficulty in deriving…

Populations and Evolution · Quantitative Biology 2021-05-25 Paul J. Hurtado , Cameron Richards

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

The effective reproduction number, R(t), is a central point in the study of infectious diseases. It establishes in an explicit way the extent of an epidemic spread process in a population. The current estimation methods for the time…

Populations and Evolution · Quantitative Biology 2021-02-26 D. C. P. Jorge , J. F. Oliveira , J. G. V. Miranda , R. F. S. Andrade , S. T. R. Pinho

Dynamics on networks is considered from the perspective of Markov stochastic processes. We partially describe the state of the system through network motifs and infer any missing data using the available information. This versatile approach…

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

We formulate a general age-of-infection epidemic model with two pathways: the symptomatic infections and the asymptomatic infections. We then calculate the basic reproduction number $\mathcal{R}_0$ and establish the final size relation. It…

Populations and Evolution · Quantitative Biology 2021-11-04 Fan Bai

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

The death toll for Covid-19 may be reduced by dividing the population into two classes, the vulnerable and the fit, with different lockdown regimes. Instead of one reproduction number there now are four parameters. These make it possible to…

Populations and Evolution · Quantitative Biology 2020-10-05 Guus Balkema

We propose a model for epidemic spreading on a finite complex network with a restriction to at most one contamination per time step. Because of a highly discrete character of the process, the analysis cannot use the continous approximation,…

Physics and Society · Physics 2013-07-23 Wojciech Ganczarek

Vector-borne diseases with reservoir cycles are complex to understand because new infections come from contacts of the vector with humans and different reservoirs. In this scenario, the basic reproductive number $\mathcal{R}^h_0$ of the…

Populations and Evolution · Quantitative Biology 2017-02-10 Esteban Vargas , Camilo Sanabria

We study a multitype SIR epidemic model where individuals are categorized into different types, and where infection spread is characterized by a next-generation matrix $M=\{m_{ij}\}$ with community fractions $\{\pi_j\}$ for the different…

Populations and Evolution · Quantitative Biology 2026-03-10 Andrea Bizzotto , Frank Ball , Tom Britton

We present an analysis of six deterministic models for epidemic spreading. The evolution of the number of individuals of each class is given by ordinary differential equations of the first order in time, which are set up by using the laws…

Biological Physics · Physics 2020-12-25 Tânia Tomé , Mário J. de Oliveira

The time varying effective reproduction number is an important parameter for communication and policy decisions during an epidemic. In this paper, we present new statistical methods for estimating the reproduction number based on the…

Methodology · Statistics 2025-10-02 Hans R. Künsch , Fabio Sigrist

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam