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In this paper, we study a reaction-diffusion vector-host epidemic model. We define the basic reproduction number $R_0$ and show that $R_0$ is a threshold parameter: if $R_0\le 1$ the disease free steady state is globally stable; if $R_0>1$…

Analysis of PDEs · Mathematics 2018-12-05 Pierre Magal , G. F. Webb , Yixiang Wu

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

Branching processes are widely used to model evolutionary and population dynamics as well as the spread of infectious diseases. To characterize the dynamics of their growth or spread, the basic reproduction number $R_0$ has received…

Populations and Evolution · Quantitative Biology 2021-09-02 Johannes Pausch , Rosalba Garcia-Millan , Gunnar Pruessner

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

This paper proposes a structural econometric approach to estimating the basic reproduction number ($\mathcal{R}_{0}$) of Covid-19. This approach identifies $\mathcal{R}_{0}$ in a panel regression model by filtering out the effects of…

Econometrics · Economics 2023-09-19 Ida Johnsson , M. Hashem Pesaran , Cynthia Fan Yang

The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to…

Populations and Evolution · Quantitative Biology 2018-09-05 Angus McLure , Kathryn Glass

This article introduces epidemia, an R package for Bayesian, regression-oriented modeling of infectious diseases. The implemented models define a likelihood for all observed data while also explicitly modeling transmission dynamics: an…

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

In this work, we revisit the basic reproduction rate $\mathcal{R}_{0}$ definition for analysis of epidemic-non-epidemic phases describing the dynamics of the discrete stochastic version of the epidemic $SIR$ model based on the Master…

Biological Physics · Physics 2007-05-23 O. E. Aiello , M. A. A. da Silva

We consider the problem of estimating the reproduction number $R_t$ of an epidemic for populations where the probability of detection of cases depends on a known covariate. We argue that in such cases the normal empirical estimator can fail…

Applications · Statistics 2020-12-04 Guido Sanguinetti

Many infectious diseases can lead to re-infection. We examined the relationship between the prevalence of repeat infection and the basic reproductive number (R0). First we solved a generic, deterministic compartmental model of re-infection…

Populations and Evolution · Quantitative Biology 2019-03-15 Joshua Feldman , Sharmistha Mishra

Analytical expressions for the basic reproduction number, R0, have been obtained in the past for a wide variety of mathematical models for infectious disease spread, along with expressions for the expected final size of an outbreak.…

Populations and Evolution · Quantitative Biology 2018-12-18 Sherry Towers , Linda J. S. Allen , Fred Brauer , Baltazar Espinoza

Human to human transmissible infectious diseases spread in a population using human interactions as its transmission vector. The early stages of such an outbreak can be modeled by a graph whose edges encode these interactions between…

Populations and Evolution · Quantitative Biology 2020-06-11 Goncalo Oliveira

The basic reproduction number R0 is a concept which originated in population dynamics, mathematical epidemiology, and ecology and is closely related to the mean number of children in branching processes.We offer below three new…

Populations and Evolution · Quantitative Biology 2023-11-30 Florin Avram , Rim Adenane , Lasko Basnarkov , Matthew Johnston

We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

Dynamical Systems · Mathematics 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons

Reproduction numbers are widely used for the estimation and prediction of epidemic spreading processes over networks. However, reproduction numbers do not enable estimation and prediction in individual communities within networks, and they…

Systems and Control · Electrical Eng. & Systems 2025-06-23 Baike She , Philip E. Paré , Matthew Hale

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

Populations and Evolution · Quantitative Biology 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

Methodology · Statistics 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could…

Dynamical Systems · Mathematics 2024-02-07 Luis Sanz-Lorenzo , Rafael Bravo de la Parra