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In the infectious disease literature, significant effort has been devoted to studying dynamics at a single scale. For example, compartmental models describing population-level dynamics are often formulated using differential equations. In…

Populations and Evolution · Quantitative Biology 2025-04-16 Yuan Yin , Jennifer A. Flegg , Mark B. Flegg

We study a multilayer SIR model with two levels of mixing, namely a global level which is uniformly mixing, and a local level with two layers distinguishing household and workplace contacts, respectively. We establish the large population…

Probability · Mathematics 2023-10-27 Madeleine Kubasch

A study of changes in the transmission of a disease, in particular, a new disease like COVID-19, requires very flexible models which can capture, among others, the effects of non-pharmacological and pharmacological measures, changes in…

Spatially constrained clustering is an important field of research, particularly when it involves changes over time. Partitioning a map is not simple since there is a vast number of possible partitions within the search space. In…

Methodology · Statistics 2025-07-14 Jessica Pavani , Rosangela Helena Loschi , Fernando Andres Quintana

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model. Through the use of a normal form coordinate transform, we are able to analytically derive the stochastic center manifold along with the…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Eric Forgoston , Lora Billings , Ira B. Schwartz

We extend the classical SIR model of infectious disease spread to account for time dependence in the parameters, which also include diffusivities. The temporal dependence accounts for the changing characteristics of testing, quarantine and…

Populations and Evolution · Quantitative Biology 2020-07-03 Zhenlin Wang , Xiaoxuan Zhang , Gregory Teichert , Mariana Carrasco-Teja , Krishna Garikipati

We formulate a generalized susceptible exposed infectious recovered (SEIR) model on a graph, describing the population dynamics of an open crowded place with an arbitrary topology. As a sample calculation, we discuss three simple cases,…

Physics and Society · Physics 2020-12-18 Andrea Nava , Alessandro Papa , Marco Rossi , Domenico Giuliano

Spatio-temporal systems exhibiting multi-scale behaviour are common in applications ranging from cyber-physical systems to systems biology, yet they present formidable challenges for computational modelling and analysis. Here we consider a…

Quantitative Methods · Quantitative Biology 2019-02-01 Michalis Michaelides , Jane Hillston , Guido Sanguinetti

Disease transmission is studied through disciplines like epidemiology, applied mathematics, and statistics. Mathematical simulation models for transmission have implications in solving public and personal health challenges. The SIR model…

Populations and Evolution · Quantitative Biology 2022-01-04 R. Jayatilaka , R. Patel , M. Brar , Y. Tang , N. M. Jisrawi , F. Chishtie , J. Drozd , S. R. Valluri

There is growing recognition in both the experimental and modelling literature of the importance of spatial structure to the dynamics of viral infections in tissues. Aided by the evolution of computing power and motivated by recent…

Quantitative Methods · Quantitative Biology 2025-07-08 Thomas Williams , James M. McCaw , James M. Osborne

The study of infectious disease propagation is essential for understanding and controlling epidemics. One of the most useful tools for gaining insights into the spread of infectious diseases is mathematical modelling. In terms of…

Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman

Epidemics are often modelled using non-linear dynamical systems observed through partial and noisy data. In this paper, we consider stochastic extensions in order to capture unknown influences (changing behaviors, public interventions,…

Applications · Statistics 2012-11-06 Joseph Dureau , Konstantinos Kalogeropoulos , Marc Baguelin

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

In this paper, we use a series of small world networks to simulate the epidemic spreading in the real world. To make our model more similar to the real world, we employ a parameter $p_{move}$ to denote its moving probability, which…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Sheng Li , Meng Meng , Hongru Ma

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

This article is devoted to the analysis of a particle system model for epidemics among a finite population with susceptible, infective and removed individuals (SIR). The infection mechanism depends on the relative distance between…

Probability · Mathematics 2020-03-10 Monia Capanna

We study a stochastic process describing the onset of spreading dynamics of an epidemic in a population composed by individuals of three classes: susceptible (S), infected (I), and recovered (R). The stochastic process is defined by local…

Statistical Mechanics · Physics 2015-05-13 David R. de Souza , Tânia Tomé

Modeling long-range epidemic spreading in a random environment, we consider a quenched disordered, $d$-dimensional contact process with infection rates decaying with the distance as $1/r^{d+\sigma}$. We study the dynamical behavior of the…

Disordered Systems and Neural Networks · Physics 2015-04-02 R. Juhász , I. A. Kovács , F. Iglói

In this paper we model the spreading of the SARS-CoV-2 in Mexico by introducing a new stochastic approximation constructed from first principles, structured on the basis of a Latent-Infectious- (Recovered or Deceased) (LI(RD)) compartmental…

Populations and Evolution · Quantitative Biology 2023-01-11 Pablo Carlos López Vázquez , Gilberto Sánchez González , Jorge Martínez Ortega , Renato Salomón Arroyo Duarte