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Viruses are submicroscopic agents that can infect all kinds of lifeforms and use their hosts' living cells to replicate themselves. Despite having some of the simplest genetic structures among all living beings, viruses are highly…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Niloy Sikder , Md. Al-Masrur Khan , Anupam Kumar Bairagi , Mehedi Masud , Jun Jiat Tiang , Abdullah-Al Nahid

Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between…

Applications · Statistics 2019-05-14 Vinny Davies , William T. Harvey , Richard Reeve , Dirk Husmeier

A prompt public health response to a new epidemic relies on the ability to monitor and predict its evolution in real time as data accumulate. The 2009 A/H1N1 outbreak in the UK revealed pandemic data as noisy, contaminated, potentially…

Liver infection is a common disease, which poses a great threat to human health, but there is still able to identify an optimal technique that can be used on large-level screening. This paper deals with ML algorithms using different data…

Machine Learning · Computer Science 2023-05-16 P. Deivendran , S. Selvakanmani , S. Jegadeesan , V. Vinoth Kumar

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

We analyze over 500 million Twitter messages from an eight month period and find that tracking a small number of flu-related keywords allows us to forecast future influenza rates with high accuracy, obtaining a 95% correlation with national…

Information Retrieval · Computer Science 2010-07-28 Aron Culotta

Influenza has been circulating in the human population and has caused three pandemics in the last century (1918 H1N1, 1957 H2N2, 1968 H3N2). The 2009 A(H1N1) was classified by the World Health Organization (WHO) as the fourth pandemic.…

Populations and Evolution · Quantitative Biology 2012-05-01 Jiankui He , Michael W. Deem

More infectious virus variants can arise from rapid mutations in their proteins, creating new infection waves. These variants can evade one's immune system and infect vaccinated individuals, lowering vaccine efficacy. Hence, to improve…

Machine Learning · Computer Science 2022-05-31 Glenda Tan Hui En , Koay Tze Erhn , Shen Bingquan

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

Fever can provide valuable information for diagnosis and prognosis of various diseases such as pneumonia, dengue, sepsis, etc., therefore, predicting fever early can help in the effectiveness of treatment options and expediting the…

Quantitative Methods · Quantitative Biology 2020-09-16 Aditya Singh , Akram Mohammed , Lokesh Chinthala , Rishikesan Kamaleswaran

Until now, design of the annual influenza vaccine has relied on phylogenetic or whole-sequence comparisons of the viral coat proteins hemagglutinin and neuraminidase, with vaccine effectiveness assumed to correlate monotonically to the…

Biomolecules · Quantitative Biology 2007-05-23 Enrique T. Munoz , Michael W. Deem

Epidemics of infectious diseases are an important threat to public health and global economies. Yet, the development of prevention strategies remains a challenging process, as epidemics are non-linear and complex processes. For this reason,…

Machine Learning · Computer Science 2020-03-31 Pieter Libin , Arno Moonens , Timothy Verstraeten , Fabian Perez-Sanjines , Niel Hens , Philippe Lemey , Ann Nowé

Graph-structured data and their related algorithms have attracted significant attention in many fields, such as influenza prediction in public health. However, the variable influenza seasonality, occasional pandemics, and domain knowledge…

Artificial Intelligence · Computer Science 2021-02-17 Jie Zhang , Pengfei Zhou , Hongyan Wu

We predict vaccine efficacy with a measure of antigenic distance between influenza A(H3N2) and candidate vaccine viruses based on amino acid substitutions in the dominant epitopes. In 2016-2017, our model predicts 19% efficacy compared to…

Populations and Evolution · Quantitative Biology 2018-04-16 Melia E. Bonomo , Michael W. Deem

Forecasting the hospitalizations caused by the Influenza virus is vital for public health planning so that hospitals can be better prepared for an influx of patients. Many forecasting methods have been used in real-time during the Influenza…

Machine Learning · Computer Science 2022-06-22 Majd Al Aawar , Ajitesh Srivastava

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology. Protein…

Biomolecules · Quantitative Biology 2015-10-06 Zixuan Cang , Lin Mu , Kedi Wu , Kristopher Opron , Kelin Xia , Guo-Wei Wei

RNA virus populations will undergo processes of mutation and selection resulting in a mixed population of viral particles. High throughput sequencing of a viral population subsequently contains a mixed signal of the underlying clones. We…

Populations and Evolution · Quantitative Biology 2014-07-31 Donatien Fotso-Chedom , Pablo R. Murcia , Chris D. Greenman

Shesop is an integrated system to make human lives more easily and to help people in terms of healthcare. Stress and influenza classification is a part of Shesop's application for a healthcare devices such as smartwatch, polar and fitbit.…

Computers and Society · Computer Science 2016-07-19 Andrien Ivander Wijaya , Ary Setijadi Prihatmanto , Rifki Wijaya

Influenza is a contagious respiratory illness that causes significant human morbidity and mortality, affecting 5-15% of the population in a typical epidemic season. Human influenza epidemics are caused by types A and B, with roughly 25% of…

Populations and Evolution · Quantitative Biology 2016-10-14 Yidan Pan , Michael W. Deem