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The worldwide surge of multiresistant microbial strains has propelled the search for alternative treatment options. The study of Protein-Protein Interactions (PPIs) has been a cornerstone in the clarification of complex physiological and…

Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

Populations and Evolution · Quantitative Biology 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

Machine learning based system are increasingly being used for sensitive tasks such as security surveillance, guiding autonomous vehicle, taking investment decisions, detecting and blocking network intrusion and malware etc. However, recent…

Artificial Intelligence · Computer Science 2017-07-12 Atul Kumar , Sameep Mehta

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Other Quantitative Biology · Quantitative Biology 2020-11-03 Xiangxie Zhang , Ben Beinke , Berlian Al Kindhi , Marco Wiering

We consider the problem of detecting an epidemic in a population where individual diagnoses are extremely noisy. The motivation for this problem is the plethora of examples (influenza strains in humans, or computer viruses in smartphones,…

Social and Information Networks · Computer Science 2014-02-07 Eli A. Meirom , Chris Milling , Constantine Caramanis , Shie Mannor , Ariel Orda , Sanjay Shakkottai

Massive datasets in the gigabyte and terabyte range combined with the availability of increasingly sophisticated statistical tools yield analyses at the boundary of what is computationally feasible. Compromising in the face of this…

Applications · Statistics 2011-01-06 Jennifer A. Tom , Janet S. Sinsheimer , Marc A. Suchard

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

Accurate real-time tracking of influenza outbreaks helps public health officials make timely and meaningful decisions that could save lives. We propose an influenza tracking model, ARGO (AutoRegression with GOogle search data), that uses…

Applications · Statistics 2015-11-17 Shihao Yang , Mauricio Santillana , S. C. Kou

Cardiovascular disease remains a leading global cause of mortality, necessitating accurate risk prediction tools. Traditional methods, such as QRISK and the Framingham heart score, exhibit limitations in their ability to incorporate…

Genomics · Quantitative Biology 2024-02-12 Farnoush Shishehbori , Zainab Awan

For epidemics control and prevention, timely insights of potential hot spots are invaluable. Alternative to traditional epidemic surveillance, which often lags behind real time by weeks, big data from the Internet provide important…

Applications · Statistics 2020-12-25 Shihao Yang , Shaoyang Ning , S. C. Kou

H5N1 highly pathogenic avian influenza (HPAI) has been recently circulating in previously unseen patterns. As the underlying causes are uncertain, we need a better understanding of the drivers of virus circulation, as they underpin the…

Populations and Evolution · Quantitative Biology 2024-11-18 Anna Gamża , Sam Lycett , Aeron Sanchez , Rowland Kao

For over a century, immunology has masterfully discovered and dissected the components of our immune system, yet its collective behavior remains fundamentally unpredictable. In this perspective, we argue that building on the learnings of…

The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature…

Populations and Evolution · Quantitative Biology 2014-09-09 Ana Carolina Arcanjo , Giovanni Mazzocco , Silviene Fabiana de Oliveira , Dariusz Plewczynski , Jan P. Radomski

We describe methods that extend (generalize or transport) causal inferences from cluster randomized trials to a target population of clusters, under a general nonparametric model that allows for arbitrary within-cluster dependence. We…

The Covid-19 pandemic has been one of the most devastating events in recent history, claiming the lives of more than 5 million people worldwide. Even with the worldwide distribution of vaccines, there is an apparent need for affordable,…

Nowadays, diseases are increasing in numbers and severity by the hour. Immunity diseases, affecting 8\% of the world population in 2017 according to the World Health Organization (WHO), is a field in medicine worth attention due to the high…

Quantitative Methods · Quantitative Biology 2023-06-23 Oumar Khlelfa , Aymen Yahyaoui , Mouna Ben Azaiz , Anwer Ncibi , Ezzedine Gazouani , Adel Ammar , Wadii Boulila

Epidemiologists increasingly use causal inference methods that rely on machine learning, as these approaches can relax unnecessary model specification assumptions. While deriving and studying asymptotic properties of such estimators is a…

Methodology · Statistics 2025-02-11 Audrey Renson , Lina Montoya , Dana E. Goin , Iván Díaz , Rachael K. Ross

Can a machine learn Machine Learning? This work trains a machine learning model to solve machine learning problems from a University undergraduate level course. We generate a new training set of questions and answers consisting of course…

Machine Learning · Computer Science 2021-07-06 Sunny Tran , Pranav Krishna , Ishan Pakuwal , Prabhakar Kafle , Nikhil Singh , Jayson Lynch , Iddo Drori

Accurate and representative data is vital for precisely reporting the impact of influenza in healthcare systems. Northern hemisphere winter 2022/23 experienced the most substantial influenza wave since the COVID-19 pandemic began in 2020.…

Populations and Evolution · Quantitative Biology 2023-10-26 Jonathon Mellor , Rachel Christie , James Guilder , Robert S Paton , Suzanne Elgohari , Conall Watson , Sarah Deeny , Thomas Ward

Mobile sensing appears as a promising solution for health inference problem (e.g., influenza-like symptom recognition) by leveraging diverse smart sensors to capture fine-grained information about human behaviors and ambient contexts.…

Machine Learning · Computer Science 2023-12-21 Guimin Dong , Lihua Cai , Mingyue Tang , Laura E. Barnes , Mehdi Boukhechba
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