Related papers: A statistical reconstruction algorithm for positro…
Positron Emission Tomography (PET) is a crucial tool in medical imaging, particularly for diagnosing diseases like cancer and Alzheimer's. The advent of Positronium Lifetime Imaging (PLI) has opened new avenues for assessing the tissue…
We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences…
Positronium Lifetime Imaging (PLI), an emerging extension of conventional positron emission tomography (PET) imaging, offers a novel window for probing the submolecular properties of biological tissues by imaging the mean lifetime of the…
Positronium Lifetime Imaging (PLI) extends positron emission tomography by using the lifetime of positronium atoms as a probe of tissue molecular architecture. In this work, we report the first PLI measurements performed with $^{52}$Mn and…
Positron emission tomographs (PET) do not measure an image directly. Instead, they measure at the boundary of the field-of-view (FOV) of PET tomograph a sinogram that consists of measurements of the sums of all the counts along the lines…
The use of Time Of Flight (TOF) in Positron Emission Tomography (PET) is expected to reduce noise on images, thanks to the additional information. In clinical routine, a common reconstruction approach is the use of maximum likelihood…
For accurate disease characterization using positron emission tomography (PET), it is desirable to image multiple radiotracers in a single scan. Conventional PET methods cannot do this due to the indistinguishable annihilation photons…
We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is…
Background: After its first ex-vivo and in-vivo demonstration, Positronium Lifetime Imaging (PLI) has received considerable interest as a potential new diagnostic biomarker. High sensitivity Positron Emission Tomography (PET) systems are…
Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…
The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…
A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the…
Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…
Single-bed whole-body positron emission tomography based on resistive plate chamber detectors (RPC-PET) has been proposed for human studies, as a complementary resource to scintillator-based PET scanners. The purpose of this work is mainly…
The integration of Time-of-Flight (TOF) information in the reconstruction process of Positron Emission Tomography (PET) yields improved image properties. However, implementing the cutting-edge model-based deep learning methods for TOF-PET…
In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…
In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…
We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…
Artificial intelligence (AI) is entering medical imaging, mainly enhancing image reconstruction. Nevertheless, improvements throughout the entire processing, from signal detection to computation, potentially offer significant benefits. This…
Positron Emission Particle Tracking (PEPT) is an imaging method that tracks individual radioactive particles. PEPT relies on the detection of back-to-back photon pairs emitted by positron annihilation. It requires an algorithm to locate the…