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We introduce an approach for global fitting of the recently published high-throughput and high accuracy clonogenic cell-survival data for therapeutic scanned proton beams. Our fitting procedure accounts for the correlation between the…

Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…

Instrumentation and Detectors · Physics 2012-02-03 C. Lang , D. Habs , P. G. Thirolf , A. Zoglauer

Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

We propose a computational model for shape, illumination and albedo inference in a pulsed time-of-flight (TOF) camera. In contrast to TOF cameras based on phase modulation, our camera enables general exposure profiles. This results in added…

Computer Vision and Pattern Recognition · Computer Science 2015-07-23 Amit Adam , Christoph Dann , Omer Yair , Shai Mazor , Sebastian Nowozin

Fluorescence Lifetime Imaging (FLI) is a critical molecular imaging modality that provides unique information about the tissue microenvironment, which is invaluable for biomedical applications. FLI operates by acquiring and analyzing photon…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Ismail Erbas , Vikas Pandey , Navid Ibtehaj Nizam , Nanxue Yuan , Amit Verma , Margarida Barosso , Xavier Intes

Prostate cancer is the most common disease in men and the second leading cause of death from cancer. Generic large imaging instruments used in cancer diagnosis have sensitivity, spatial resolution, and contrast inadequate for the task of…

In transportation, Weigh-in motion (WIM) stations, Electronic Toll Collection (ETC) systems, Closed-circuit Television (CCTV) are widely deployed to collect data at different locations. Vehicle re-identification, by matching the same…

Applications · Statistics 2024-11-06 Diyi Liu , Yangsong Gu , Lee D. Han

Mixture of autoregressions (MoAR) models provide a model-based approach to the clustering of time series data. The maximum likelihood (ML) estimation of MoAR models requires the evaluation of products of large numbers of densities of normal…

Computation · Statistics 2016-10-19 Hien D Nguyen , Geoffrey J McLachlan , Pierre Orban , Pierre Bellec , Andrew L Janke

Objective: The most relevant source of signal contamination in the cardiac electrophysiology (EP) laboratory is the ubiquitous powerline interference (PLI). To reduce this perturbation, algorithms including common fixed bandwidth and…

Medical Physics · Physics 2024-01-18 Miguel Martinez-Iniesta , Juan Rodenas , Jose J. Rieta , Raul Alcaraz

MTV is increasingly recognized as an accurate estimate of disease burden, which has prognostic value, but its implementation has been hindered by the time-consuming need for manual segmentation of images. Automated quantitation using…

Positron Emission Tomography (PET) is an important tool for studying Alzheimer's disease (AD). PET scans can be used as diagnostics tools, and to provide molecular characterization of patients with cognitive disorders. However, multiple…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Bo Zhou , Rui Wang , Ming-Kai Chen , Adam P. Mecca , Ryan S. O'Dell , Christopher H. Van Dyck , Richard E. Carson , James S. Duncan , Chi Liu

Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…

Tissues and Organs · Quantitative Biology 2020-01-22 Michele Piana , Giacomo Caviglia , Sara Sommariva

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong

We present an analytical inversion technique which can be used to recover ionization probabilities from spatially averaged data in an N-dimensional detection scheme. The solution is given as a power series in intensity. For this reason, we…

Quantum Physics · Physics 2015-05-18 J. Strohaber , A. A. Kolomenskii , H. A. Schuessler

In this paper, we introduce a new two-parameter lifetime distribution, called the exponential-generalized truncated logarithmic (EGTL) distribution, by compounding the exponential and generalized truncated logarithmic distributions. Our…

Statistics Theory · Mathematics 2018-09-28 Mohieddine Rahmouni , Ayman Orabi

Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…

Medical Physics · Physics 2026-02-18 Gábor Bíró , Ákos Sudár , Zsófia Jólesz , Gábor Papp , Gergely Gábor Barnaföldi

Radio polarisation images of the jets of Active Galactic Nuclei (AGN) can provide a deep insight into the launching and collimation mechanisms of relativistic jets. However, even at VLBI scales, resolution is often a limiting factor in the…

Astrophysics of Galaxies · Physics 2016-09-07 Colm P. Coughlan , Denise C. Gabuzda

In cross-modal retrieval tasks, such as image-to-report and report-to-image retrieval, accurately aligning medical images with relevant text reports is essential but challenging due to the inherent ambiguity and variability in medical data.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Shreyank N Gowda , Xiaobo Jin , Christian Wagner

PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

Instrumentation and Detectors · Physics 2025-04-24 Stephan Naunheim , Luis Lopes de Paiva , Vanessa Nadig , Yannick Kuhl , Stefan Gundacker , Florian Mueller , Volkmar Schulz

Orthogonal-strip planar high-purity germanium (HPGe) detectors can reconstruct three-dimensional (3D) positions of photon interactions through analysis of parameters extracted from multiple charge signals. The conventional method…

Instrumentation and Detectors · Physics 2025-07-25 Qiuli Zhang , Peng Zhang , Wenhhan Dai , Mingxin Yang , Yang Tian , Ming Zeng , Hao Ma , Zhi Zeng
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