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To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Numerous statistical methods have been developed to explore genomic imprinting and maternal effects, which are causes of parent-of-origin patterns in complex human diseases. However, most of them either only model one of these two…

Methodology · Statistics 2024-01-02 Pooya Aavani , Alexandre Trindade , Fangyuan Zhang

In this study we address the feasibility and main properties of a positron emission tomograph (PET) based on RPCs. The concept, making use of the converter-plate principle, takes advantage of the intrinsic layered structure of RPCs and its…

Instrumentation and Detectors · Physics 2009-11-07 A. Blanco , V. Chepel , R. Ferreira-Marques , P. Fonte , M. I. Lopes , V. Peskov , A. Policarpo

Magnetic materials phase reconstruction from Lorentz transmission electron microscopy (LTEM) measurements has traditionally been achieved using longstanding methods such as off-axis holography (OAH) and the transport-of-intensity equation…

The Pulmonary Function Test (PFT) is an widely utilized and rigorous classification test for lung function evaluation, serving as a comprehensive tool for lung diagnosis. Meanwhile, Electrical Impedance Tomography (EIT) is a rapidly…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Shuzhe Chen , Li Li , Zhichao Lin , Ke Zhang , Ying Gong , Lu Wang , Xu Wu , Maokun Li , Yuanlin Song , Fan Yang , Shenheng Xu

Time-of-flight (TOF) information provides more accurate location data for annihilation photons, thereby enhancing the quality of PET reconstruction images and reducing noise. List-mode reconstruction has a significant advantage in handling…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Rui Hu , Chenxu Li , Kun Tian , Jianan Cui , Yunmei Chen , Huafeng Liu

Probabilistic inversion methods based on Markov chain Monte Carlo (MCMC) simulation are well suited to quantify parameter and model uncertainty of nonlinear inverse problems. Yet, application of such methods to CPU-intensive forward models…

Geophysics · Physics 2017-01-11 M. Rosas-Carbajal , N. Linde , T. Kalscheuer , J. A. Vrugt

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

This article presents a methodology that aims to model and to provide predictive capabilities for the lifetime of Proton Exchange Membrane Fuel Cell (PEMFC). The approach integrates parametric identification, dynamic modeling, and Extended…

Longitudinal imaging studies are essential to understanding the neural development of neuropsychiatric disorders, substance use disorders, and the normal brain. The main objective of this paper is to develop a two-stage adjusted…

Applications · Statistics 2011-08-12 Xiaoyan Shi , Joseph G. Ibrahim , Jeffrey Lieberman , Martin Styner , Yimei Li , Hongtu Zhu

Fourier ptychographic microscopy (FPM) is a novel computational coherent imaging technique for high space-bandwidth product imaging. Mathematically, Fourier ptychographic (FP) reconstruction can be implemented as a phase retrieval…

Computer Vision and Pattern Recognition · Computer Science 2016-07-19 Liheng Bian , Jinli Suo , Jaebum Chung , Xiaoze Ou , Changhuei Yang , Feng Chen , Qionghai Dai

Sequential whole-body 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scans are regarded as the imaging modality of choice for the assessment of treatment response in the lymphomas because they detect treatment response when…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Kai-Chieh Liang , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Integral projection models (IPMs) are widely used to study population growth and the dynamics of demographic structure (e.g. age and size distributions) within a population.These models use data on individuals' growth, survival, and…

Methodology · Statistics 2024-11-14 Yunzhe Zhou , Giles Hooker

In this paper, we mainly focus on the penalized maximum likelihood estimation (MLE) of the high-dimensional approximate factor model. Since the current estimation procedure can not guarantee the positive definiteness of the error covariance…

Computation · Statistics 2019-01-18 Shaoxin Wang , Hu Yang , Chaoli Yao

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Complete time of flight (TOF) sinograms of state-of-the-art TOF PET scanners have a large memory footprint. Currently, they contain ~4e9 data bins which amount to ~17GB in 32bit floating point precision. Using iterative algorithms to…

Medical Physics · Physics 2022-05-24 Georg Schramm , Martin Holler

Precise quantitative delineation of tumor hypoxia is essential in radiation therapy treatment planning to improve the treatment efficacy by targeting hypoxic sub-volumes. We developed a combined imaging system of positron emission…

Electrical properties (EPs) of tissues, conductivity and permittivity, are modulated by the ionic and water content, which change in presence of pathologies. Information on tissues EPs can be used e.g. as an endogenous biomarker in…

The aim of this paper is to propose an optimal control optimization algorithm for reconstructing admittivity distributions (i.e., both conductivity and permittivity) from multi-frequency micro-electrical impedance tomography. A convergent…

Analysis of PDEs · Mathematics 2014-03-25 Habib Ammari , Laure Giovangigli , Loc Hoang Nguyen , Jin-Keun Seo

We study the problem of computing the maximum likelihood estimator (MLE) of multivariate log-concave densities. Our main result is the first computationally efficient algorithm for this problem. In more detail, we give an algorithm that, on…

Data Structures and Algorithms · Computer Science 2018-12-14 Ilias Diakonikolas , Anastasios Sidiropoulos , Alistair Stewart