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With the recent move towards sequencing of accurate long reads, finding solutions that support efficient analysis of these reads becomes more necessary. The long execution time required for sequence alignment of long reads negatively…

Hardware Architecture · Computer Science 2023-10-25 Taha Shahroodi , Michael Miao , Joel Lindegger , Stephan Wong , Onur Mutlu , Said Hamdioui

Various processing-in-memory (PIM) accelerators based on various devices, micro-architectures, and interfaces have been proposed to accelerate deep neural networks (DNNs). How to deploy DNNs onto PIM-based accelerators is the key to explore…

Hardware Architecture · Computer Science 2024-11-15 Xiaotian Sun , Xinyu Wang , Wanqian Li , Yinhe Han , Xiaoming Chen

The performance gap between memory and processor has grown rapidly. Consequently, the energy and wall-clock time costs associated with moving data between the CPU and main memory predominate the overall computational cost. The…

Hardware Architecture · Computer Science 2024-03-01 Qingcai Jiang , Shaojie Tan , Junshi Chen , Hong An

Indexing is a well-known database technique used to facilitate data access and speed up query processing. Nevertheless, the construction and modification of indexes are very expensive. In traditional approaches, all records in the database…

Databases · Computer Science 2023-06-22 Wojciech Macyna , Michal Kukowski

Compute-in-memory (CiM) is a promising approach to improving the computing speed and energy efficiency in dataintensive applications. Beyond existing CiM techniques of bitwise logic-in-memory operations and dot product operations, this…

Hardware Architecture · Computer Science 2023-01-03 Yiming Chen , Yushen Fu , Mingyen Lee , Sumitha George , Yongpan Liu , Vijaykrishnan Narayanan , Huazhong Yang , Xueqing Li

The algorithm of brain learning and memory is still undetermined. The backpropagation algorithm of artificial neural networks was thought not suitable for brain cortex, and there is a lack of algorithm for memory engram. We designed a brain…

Neural and Evolutionary Computing · Computer Science 2020-10-29 Yifei Mao

Large Language Model (LLM) inference requires substantial computational resources, yet CPU-based inference remains essential for democratizing AI due to the widespread availability of CPUs compared to specialized accelerators. However,…

Hardware Architecture · Computer Science 2025-10-01 Jingyao Zhang , Jaewoo Park , Jongeun Lee , Elaheh Sadredini

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

In-DRAM Processing-In-Memory (DRAM-PIM) has emerged as a promising approach to accelerate memory-intensive workloads by mitigating data transfer overhead between DRAM and the host processor. Bit-serial DRAM-PIM architectures, further…

Hardware Architecture · Computer Science 2025-12-11 Siyuan Ma , Jiajun Hu , Jeeho Ryoo , Aman Arora , Lizy Kurian John

Bit-serial Processing-In-Memory (PIM) is an attractive paradigm for accelerator architectures, for parallel workloads such as Deep Learning (DL), because of its capability to achieve massive data parallelism at a low area overhead and…

Hardware Architecture · Computer Science 2023-11-21 Aman Arora , Jian Weng , Siyuan Ma , Tony Nowatzki , Lizy K. John

Compute-in-memory (CIM) is an efficient method for implementing deep neural networks (DNNs) but suffers from substantial overhead from analog-to-digital converters (ADCs), especially as ADC precision increases. Low-precision ADCs can reduce…

Hardware Architecture · Computer Science 2025-03-14 Jiyoon Kim , Kang Eun Jeon , Yulhwa Kim , Jong Hwan Ko

This paper develops a memory-efficient approach for Sequential Pattern Mining (SPM), a fundamental topic in knowledge discovery that faces a well-known memory bottleneck for large data sets. Our methodology involves a novel hybrid trie data…

Databases · Computer Science 2024-07-30 Amin Hosseininasab , Willem-Jan van Hoeve , Andre A. Cire

Motivation: The ability to generate massive amounts of sequencing data continues to overwhelm the processing capability of existing algorithms and compute infrastructures. In this work, we explore the use of hardware/software co-design and…

Computational Engineering, Finance, and Science · Computer Science 2020-10-29 Mohammed Alser , Hasan Hassan , Akash Kumar , Onur Mutlu , Can Alkan

Edge devices equipped with computer vision must deal with vast amounts of sensory data with limited computing resources. Hence, researchers have been exploring different energy-efficient solutions such as near-sensor processing, in-sensor…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Md Abdullah-Al Kaiser , Gourav Datta , Zixu Wang , Ajey P. Jacob , Peter A. Beerel , Akhilesh R. Jaiswal

DNA sequencing is the physical/biochemical process of identifying the location of the four bases (Adenine, Guanine, Cytosine, Thymine) in a DNA strand. As semiconductor technology revolutionized computing, modern DNA sequencing technology…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-06 S. Karen Khatamifard , Zamshed Chowdhury , Nakul Pande , Meisam Razaviyayn , Chris Kim , Ulya R. Karpuzcu

Disentanglement of constituent factors of a sensory signal is central to perception and cognition and hence is a critical task for future artificial intelligence systems. In this paper, we present a compute engine capable of efficiently…

Emerging Technologies · Computer Science 2023-06-07 Jovin Langenegger , Geethan Karunaratne , Michael Hersche , Luca Benini , Abu Sebastian , Abbas Rahimi

Digital Computing-in-Memory (DCIM) is an innovative technology that integrates multiply-accumulation (MAC) logic directly into memory arrays to enhance the performance of modern AI computing. However, the need for customized memory cells…

Genome-to-genome comparisons require designating anchor points, which are given by Maximum Exact Matches (MEMs) between their sequences. For large genomes this is a challenging problem and the performance of existing solutions, even in…

Data Structures and Algorithms · Computer Science 2018-05-24 Szymon Grabowski , Wojciech Bieniecki

Deep learning-based image matching methods play a crucial role in computer vision, yet they often suffer from substantial computational demands. To tackle this challenge, we present HCPM, an efficient and detector-free local…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Ying Chen , Yong Liu , Kai Wu , Qiang Nie , Shang Xu , Huifang Ma , Bing Wang , Chengjie Wang

Deep Neural Networks (DNNs) have transformed the field of machine learning and are widely deployed in many applications involving image, video, speech and natural language processing. The increasing compute demands of DNNs have been widely…

Machine Learning · Computer Science 2021-08-17 Sourjya Roy , Mustafa Ali , Anand Raghunathan