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Related papers: FiltPIM: In-Memory Filter for DNA Sequencing

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In this paper, we present FLiMS, a highly-efficient and simple parallel algorithm for merging two sorted lists residing in banked and/or wide memory. On FPGAs, its implementation uses fewer hardware resources than the state-of-the-art…

Hardware Architecture · Computer Science 2022-03-08 Philippos Papaphilippou , Wayne Luk , Chris Brooks

Non-intrusive load monitoring (NILM) aims at energy consumption and appliance state information retrieval from aggregated consumption measurements, with the help of signal processing and machine learning algorithms. Representation learning…

Signal Processing · Electrical Eng. & Systems 2022-09-09 Matthias Kahl , Daniel Jorde , Hans-Arno Jacobsen

Basecalling, an essential step in many genome analysis studies, relies on large Deep Neural Networks (DNNs) to achieve high accuracy. Unfortunately, these DNNs are computationally slow and inefficient, leading to considerable delays and…

Hardware Architecture · Computer Science 2023-11-28 Taha Shahroodi , Gagandeep Singh , Mahdi Zahedi , Haiyu Mao , Joel Lindegger , Can Firtina , Stephan Wong , Onur Mutlu , Said Hamdioui

Large language models (LLMs) have exhibited impressive reasoning abilities on a wide range of complex tasks. However, enhancing these capabilities through post-training remains resource intensive, particularly in terms of data and…

Artificial Intelligence · Computer Science 2025-08-13 Shuo Cai , Su Lu , Qi Zhou , Kejing Yang , Zhijie Sang , Congkai Xie , Hongxia Yang

MRI-based medical imaging has become indispensable in modern clinical diagnosis, particularly for brain tumor detection. However, the rapid growth in data volume poses challenges for conventional diagnostic approaches. Although deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Hayder Saad Abdulbaqi , Mohammed Hadi Rahim , Mohammed Hassan Hadi , Haider Ali Aboud , Ali Hussein Allawi

In-memory computing is an emerging non-von Neumann computing paradigm where certain computational tasks are performed in memory by exploiting the physical attributes of the memory devices. Memristive devices such as phase-change memory…

Emerging Technologies · Computer Science 2020-04-08 Anastasios Petropoulos , Irem Boybat , Manuel Le Gallo , Evangelos Eleftheriou , Abu Sebastian , Theodore Antonakopoulos

We introduce a parallel algorithmic architecture for metagenomic sequence assembly, termed MetaPar, which allows for significant reductions in assembly time and consequently enables the processing of large genomic datasets on computers with…

Quantitative Methods · Quantitative Biology 2013-11-18 Minji Kim , Jonathan G. Ligo , Amin Emad , Farzad Farnoud , Olgica Milenkovic , Venugopal V. Veeravalli

Searching for similar genomic sequences is an essential and fundamental step in biomedical research and an overwhelming majority of genomic analyses. State-of-the-art computational methods performing such comparisons fail to cope with the…

Data Structures and Algorithms · Computer Science 2024-07-11 Mohammed Alser , Julien Eudine , Onur Mutlu

In the era of high throughput DNA sequencing (HTS) technologies, calculating the edit distance (i.e., the minimum number of substitutions, insertions, and deletions between a pair of sequences) for billions of genomic sequences is the…

Genomics · Quantitative Biology 2017-08-17 Mohammed Alser , Onur Mutlu , Can Alkan

Today's systems are overwhelmingly designed to move data to computation. This design choice goes directly against at least three key trends in systems that cause performance, scalability and energy bottlenecks: (1) data access from memory…

Hardware Architecture · Computer Science 2019-03-12 Onur Mutlu , Saugata Ghose , Juan Gómez-Luna , Rachata Ausavarungnirun

Transformer-based models, such as BERT and ViT, have achieved state-of-the-art results across different natural language processing (NLP) and computer vision (CV) tasks. However, these models are extremely memory intensive during their…

Computation and Language · Computer Science 2023-05-31 Arash Ardakani , Altan Haan , Shangyin Tan , Doru Thom Popovici , Alvin Cheung , Costin Iancu , Koushik Sen

Patent analysis and mining are time-consuming and costly processes for companies, but nevertheless essential if they are willing to remain competitive. To face the overload induced by numerous patents, the idea is to automatically filter…

Computation and Language · Computer Science 2021-07-05 Théo Ding , Walter Vermeiren , Sylvie Ranwez , Binbin Xu

Parameter-efficient transfer learning (PETL) is proposed as a cost-effective way to transfer pre-trained models to downstream tasks, avoiding the high cost of updating entire large-scale pre-trained models (LPMs). In this work, we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Yijin Huang , Pujin Cheng , Roger Tam , Xiaoying Tang

Modern Machine Learning (ML) training on large-scale datasets is a very time-consuming workload. It relies on the optimization algorithm Stochastic Gradient Descent (SGD) due to its effectiveness, simplicity, and generalization performance.…

Hardware Architecture · Computer Science 2024-09-30 Steve Rhyner , Haocong Luo , Juan Gómez-Luna , Mohammad Sadrosadati , Jiawei Jiang , Ataberk Olgun , Harshita Gupta , Ce Zhang , Onur Mutlu

Motivation: Protein-to-genome alignment is critical to annotating genes in non-model organisms. While there are a few tools for this purpose, all of them were developed over ten years ago and did not incorporate the latest advances in…

Genomics · Quantitative Biology 2022-12-29 Heng Li

Traditional Von Neumann computing is falling apart in the era of exploding data volumes as the overhead of data transfer becomes forbidding. Instead, it is more energy-efficient to fuse compute capability with memory where the data reside.…

Performance optimization is the art of continuous seeking a harmonious mapping between the application domain and hardware. Recent years have witnessed a surge of deep learning (DL) applications in industry. Conventional wisdom for…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-27 Guoping Long , Jun Yang , Wei Lin

Ethical and privacy issues inherent in artificial intelligence (AI) applications have been a growing concern with the rapid spread of deep learning. Machine unlearning (MU) is the research area that addresses these issues by making a…

Machine Learning · Computer Science 2024-09-26 Tomoya Yamashita , Masanori Yamada , Takashi Shibata

Deep neural networks (DNNs) have revolutionized the field of artificial intelligence and have achieved unprecedented success in cognitive tasks such as image and speech recognition. Training of large DNNs, however, is computationally…

Transformers, while revolutionary, face challenges due to their demanding computational cost and large data movement. To address this, we propose HyFlexPIM, a novel mixed-signal processing-in-memory (PIM) accelerator for inference that…

Hardware Architecture · Computer Science 2025-06-03 Chang Eun Song , Priyansh Bhatnagar , Zihan Xia , Nam Sung Kim , Tajana Rosing , Mingu Kang
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