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For various optimization methods, gradient descent-based algorithms can achieve outstanding performance and have been widely used in various tasks. Among those commonly used algorithms, ADAM owns many advantages such as fast convergence…

Neural and Evolutionary Computing · Computer Science 2021-05-05 Jiyang Bai , Yuxiang Ren , Jiawei Zhang

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

In this thesis we propose new methods for crossover operator namely: cut on worst gene (COWGC), cut on worst L+R gene (COWLRGC) and Collision Crossovers. And also we propose several types of mutation operator such as: worst gene with random…

Neural and Evolutionary Computing · Computer Science 2018-01-26 Esra'a O Alkafaween

One of the problems in applying Genetic Algorithm is that there is some situation where the evolutionary process converges too fast to a solution which causes it to be trapped in local optima. To overcome this problem, a proper diversity in…

Neural and Evolutionary Computing · Computer Science 2011-09-02 Chaiwat Jassadapakorn , Prabhas Chongstitvatana

Gradient-based optimization is a key ingredient of variational quantum algorithms, with applications ranging from quantum machine learning to quantum chemistry and simulation. The parameter-shift rule provides a hardware-friendly method for…

Quantum Physics · Physics 2025-10-08 Leonardo Banchi , Dominic Branford , Chetan Waghela

Purpose: To develop a multi-criteria optimization framework for image guided radiotherapy. Methods: An algorithm is proposed for a multi-criteria framework for the purpose of patient setup verification decision processes. Optimal patient…

Medical Physics · Physics 2011-08-16 Brian Winey , James Balter

In proton therapy of low-grade glioma (LGG) patients, contrast-enhancing brain lesions (CEBLs) on magnetic resonance imaging are considered predictive of late radiation-induced lesions. From the observation that CEBLs tend to concentrate in…

Medical Physics · Physics 2026-04-16 Tim Ortkamp , Habiba Sallem , Semi Harrabi , Martin Frank , Oliver Jäkel , Julia Bauer , Niklas Wahl

Proton radiography combined with X-ray computed tomography (CT) has been proposed to obtain a patient-specific calibration curve and reduce range uncertainties in cancer treatment with charged particles. The main aim of this study was to…

Quantum algorithms are emerging tools in the design of functional materials due to their powerful solution space search capability. How to balance the high price of quantum computing resources and the growing computing needs has become an…

Quantum Physics · Physics 2024-05-13 Zhihao Xu , Wenjie Shang , Seongmin Kim , Alexandria Bobbitt , Eungkyu Lee , Tengfei Luo

Gradient porous structured materials possess significant potential of being applied in many engineering fields. To accelerate the design process of infill graded microstructures, a novel asymptotic homogenisation topology optimisation…

Computational Engineering, Finance, and Science · Computer Science 2019-12-18 Dingchuan Xue , Yichao Zhu , Shaoshuai Li , Chang Liu , Weisheng Zhang , Xu Guo

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Machine learning and optimization algorithms have been widely applied in the design and optimization for photonic devices. In this article, we briefly review recent progress of this field of research and show some data-driven applications…

Optics · Physics 2020-07-15 Tian Zhang , Qi Liu , Yihang Dan , Shuai Yu , Xu Han , Jian Dai , Kun Xu

We present a stabilised finite element method for modelling proton transport in tissue, incorporating both inelastic energy loss and elastic angular scattering. A key innovation is a positivity-preserving formulation that guarantees…

Numerical Analysis · Mathematics 2025-06-03 Ben S. Ashby , Abdalaziz Hamdan , Tristan Pryer

In this article, we present a general mode-conversion algorithm allowing to build an optical system composed of an alternation of phase masks and free propagations. The originality of our approach lies in the introduction of free parameters…

Computational Physics · Physics 2020-06-08 Nicolas Barré

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

Medical Physics · Physics 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

Background: Proton arc therapy is an emerging radiation therapy technique where either the gantry or the patient continuously rotates during the irradiation treatment. One of the perceived advantages of proton arc therapy is the reduced…

Medical Physics · Physics 2023-10-20 Viktor Wase , Otte Marthin , Albin Fredriksson , Anton Finnson

Molecular discovery has brought great benefits to the chemical industry. Various molecule design techniques are developed to identify molecules with desirable properties. Traditional optimization methods, such as genetic algorithms,…

Biomolecules · Quantitative Biology 2025-11-05 Chris Zhuang , Debadyuti Mukherjee , Yingzhou Lu , Tianfan Fu , Ruqi Zhang

Radiologists often mix medical image reading strategies, including inspection of individual modalities and local image regions, using information at different locations from different images independently as well as concurrently. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiangcen Wu , Shaheer U. Saeed , Yipei Wang , Ester Bonmati Coll , Yipeng Hu

Consider convex optimization problems subject to a large number of constraints. We focus on stochastic problems in which the objective takes the form of expected values and the feasible set is the intersection of a large number of convex…

Machine Learning · Statistics 2015-11-13 Mengdi Wang , Yichen Chen , Jialin Liu , Yuantao Gu

The $(1+(\lambda,\lambda))$ genetic algorithm is one of the few algorithms for which a super-constant speed-up through the use of crossover could be proven. So far, this algorithm has been used with parameters based also on intuitive…

Neural and Evolutionary Computing · Computer Science 2016-08-01 Benjamin Doerr