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Purpose: Beam angle selection is critical in proton therapy treatment planning, yet automated approaches remain underexplored. This study presents and evaluates GAMBAS, a novel, fast machine learning model for automatic beam angle…

In topologically-protected quantum computation, quantum gates can be carried out by adiabatically braiding two-dimensional quasiparticles, reminiscent of entangled world lines. Bonesteel et al. [Phys. Rev. Lett. 95, 140503 (2005)], as well…

Quantum Physics · Physics 2013-02-14 Ross B. McDonald , Helmut G. Katzgraber

Universal fault-tolerant quantum computers will require error-free execution of long sequences of quantum gate operations, which is expected to involve millions of physical qubits. Before the full power of such machines will be available,…

This paper describes the algorithm and examines the performance of an IMRT beam-angle optimization (BAO) system. In this algorithm successive sets of beam angles are selected from a set of predefined directions using a fast simulated…

Medical Physics · Physics 2009-11-10 David Djajaputra , Qiuwen Wu , Yan Wu , Radhe Mohan

Glioblastoma is a highly invasive brain tumor, whose cells infiltrate surrounding normal brain tissue beyond the lesion outlines visible in the current medical scans. These infiltrative cells are treated mainly by radiotherapy. Existing…

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution, which are characterized by successfully finding robust solutions for optimization problems. Here, we propose a subroutine-based quantum genetic…

Quantum Physics · Physics 2024-06-07 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

We propose a method that combines fixed point algorithms with a neural network to optimize jointly discrete and continuous variables in millimeter-wave communication systems, so that the users' rates are allocated fairly in a well-defined…

Information Theory · Computer Science 2021-08-23 Rafail Ismayilov , Renato L. G. Cavalcante , Sławomir Stańczak

Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range uncertainties, and computational complexity. This review…

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

Genetic algorithms are modeled after the biological evolutionary processes that use natural selection to select the best species to survive. They are heuristics based and low cost to compute. Genetic algorithms use selection, crossover, and…

Neural and Evolutionary Computing · Computer Science 2020-05-28 Mee Seong Im , Venkat R. Dasari

The article presents a study of the Particle Swarm optimization method for scheduling problem. To improve the method's performance a restriction of particles' velocity and an evolutionary meta-optimization were realized. The approach…

Neural and Evolutionary Computing · Computer Science 2020-06-22 Pavel Matrenin , Viktor Sekaev

Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…

Instrumentation and Detectors · Physics 2020-07-28 F. Ulrich-Pur , T. Bergauer , A. Burker , S. Hatamikia , A. Hirtl , C. Irmler , S. Kaser , P. Paulitsch , F. Pitters , V. Teufelhart

Analyzing large datasets to select optimal features is one of the most important research areas in machine learning and data mining. This feature selection procedure involves dimensionality reduction which is crucial in enhancing the…

Neural and Evolutionary Computing · Computer Science 2024-09-24 Zhila Yaseen Taha , Abdulhady Abas Abdullah , Tarik A. Rashid

This paper presents an evolutionary algorithm with a new goal-sequence domination scheme for better decision support in multi-objective optimization. The approach allows the inclusion of advanced hard/soft priority and constraint…

Artificial Intelligence · Computer Science 2011-06-02 E. F. Khor , T. H. Lee , R. Sathikannan , K. C. Tan

This work presents a novel lattice-based methodology for incorporating multidimensional constraints into continuous decision variables within a genetic algorithm (GA) framework. The proposed approach consolidates established transcription…

Neural and Evolutionary Computing · Computer Science 2024-10-17 Cameron D. Harris , Kevin B. Schroeder , Jonathan Black

The experimenter must perform a legitimate search in the entire set of feasible censoring schemes to identify the optimal type II progressive censoring scheme, when applied to a life-testing experiment. Current recommendations are limited…

Applications · Statistics 2025-07-29 Ujjwal Roy , Ritwik Bhattacharya

In recent decades, cold atom experiments have become increasingly complex. While computers control most parameters, optimization is mostly done manually. This is a time-consuming task for a high-dimensional parameter space with unknown…

Quantum Physics · Physics 2013-09-03 I. Geisel , K. Cordes , J. Mahnke , S. Jöllenbeck , J. Ostermann , J. Arlt , W. Ertmer , C. Klempt

The major advantage of proton therapy over conventional radiotherapy is the dose deposition pattern, enabling precise coverage of the tumour volume while sparing nearby healthy tissues. However, accurate control of the proton beam range…

Medical Physics · Physics 2025-04-01 Magdalena Kołodziej

Large variability between cell lines brings a difficult optimization problem of drug selection for cancer therapy. Standard approaches use prediction of value for this purpose, corresponding e.g. to expected value of their distribution.…

Quantitative Methods · Quantitative Biology 2022-09-15 Jarek Duda