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Radiation therapy is a critical component of cancer treatment. However, the delivery of radiation poses inherent challenges, particularly in minimizing radiation exposure to healthy organs surrounding the tumor site. One significant…

Optimization and Control · Mathematics 2024-01-22 Keshav Kumar K. , NVSL Narasimham

This paper explores the use of genetic algorithms for the design of networks, where the demands on the network fluctuate in time. For varying network constraints, we find the best network using the standard genetic algorithm operators such…

Neural and Evolutionary Computing · Computer Science 2009-11-10 Matthew J. Berryman , Andrew Allison , Derek Abbott

Evolutionary algorithms, inspired by natural evolution, aim to optimize difficult objective functions without computing derivatives. Here we detail the relationship between population genetics and evolutionary optimization and formulate a…

Populations and Evolution · Quantitative Biology 2023-07-19 Jakub Otwinowski , Colin LaMont

In this investigation, we propose several algorithms to recover the location and intensity of a radiation source located in a simulated 250 m x 180 m block in an urban center based on synthetic measurements. Radioactive decay and detection…

Applications · Statistics 2016-07-05 Razvan Stefanescu , Kathleen Schmidt , Jason Hite , Ralph Smith , John Mattingly

Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…

One of the grand challenges in intensity-modulated radiotherapy (IMRT) planning is to optimize the beam angles in a reasonable computation time. To demonstrate the value of prior knowledge on improving the efficiency of beam angle…

Medical Physics · Physics 2018-11-06 Yong-Jie Li

This study presents a comprehensive approach for optimizing the acquisition, utilization, and maintenance of ABLVR vascular robots in healthcare settings. Medical robotics, particularly in vascular treatments, necessitates precise resource…

Neural and Evolutionary Computing · Computer Science 2024-07-03 Zixi Wang , Yubo Huang , Yukai Zhang , Yifei Sheng , Xin Lai , Peng Lu

Radiation therapy is considered to be one of important treatment protocols for cancers. Radiation therapy employs several beams of ionizing radiation to kill cancer tumors, but such irradiation also causes damage to normal tissues.…

Optimization and Control · Mathematics 2016-12-06 Shogo Kishimoto , Makoto Yamashita

In this paper, a novel knowledge-based genetic algorithm for path planning of a mobile robot in unstructured complex environments is proposed, where five problem-specific operators are developed for efficient robot path planning. The…

Robotics · Computer Science 2022-09-07 Yanrong Hu , Simon X. Yang

Effective therapy of complex diseases requires control of highly non-linear complex networks that remain incompletely characterized. In particular, drug intervention can be seen as control of signaling in cellular networks. Identification…

Quantitative Methods · Quantitative Biology 2009-09-03 Jacob D. Feala , Jorge Cortes , Phillip M. Duxbury , Carlo Piermarocchi , Andrew D. McCulloch , Giovanni Paternostro

Radiation therapy treatment planning can be viewed as an iterative hyperparameter tuning process to balance conflicting clinical goals. In this work, we investigated the performance of modern Bayesian Optimization (BO) methods on automated…

Medical Physics · Physics 2023-02-15 Qingying Wang , Ruoxi Wang , Jiacheng Liu , Fan Jiang , Haizhen Yue , Yi Du , Hao Wu

Fluence map optimization for intensity-modulated radiation therapy planning can be formulated as a large-scale inverse problem with competing objectives and constraints associated with the tumors and organs-at-risk. Unfortunately,…

Optimization and Control · Mathematics 2022-02-17 Kelsey Maass , Minsun Kim , Aleksandr Aravkin

Fluid antenna is a new reconfigurable antenna technology that can dynamically adjust the positions or ports of radiating elements and therefore provides a new degree of freedom for wireless communications. However, the associated port…

Information Theory · Computer Science 2026-05-15 Gan Zheng , Fei Liu , Qingfu Zhang

This manuscript proposes an optimization framework to find the tailor-made functionally graded material (FGM) profiles for thermoelastic applications. This optimization framework consists of (1) a random profile generation scheme, (2) deep…

Computational Engineering, Finance, and Science · Computer Science 2024-08-27 Piyush Agrawal , Ihina Mahajan , Shivam Choubey , Manish Agrawal

This research addresses the crucial issue of pollution from aircraft operations, focusing on optimizing both gate allocation and runway scheduling simultaneously, a novel approach not previously explored. The study presents an innovative…

Neural and Evolutionary Computing · Computer Science 2024-03-01 Fernando Guedan Pecker , Cristian Ramirez Atencia

Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

The interaction of relativistically intense lasers with opaque targets represents a highly non-linear, multi-dimensional parameter space. This limits the utility of sequential 1D scanning of experimental parameters for the optimisation of…

This paper presents a new type of genetic algorithm for the set covering problem. It differs from previous evolutionary approaches first because it is an indirect algorithm, i.e. the actual solutions are found by an external decoder…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

Vectorial Genetic Programming (Vec-GP) extends GP by allowing vectors as input features along regular, scalar features, using them by applying arithmetic operations component-wise or aggregating vectors into scalars by some aggregation…

Neural and Evolutionary Computing · Computer Science 2023-03-07 Philipp Fleck , Stephan Winkler , Michael Kommenda , Michael Affenzeller
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