Related papers: A nonlocal model describing tumor angiogenesis
Angiogenesis is the formation of new blood vessels from the existing vessels. During tumour angiogenesis, tumour cells secret a number of chemical substrates called tumour angiogenic factors (TAFs). These factors diffuse through the…
In this paper we study the growth of a tumor colony of multilayer type and focus on how the tumor grows from a near flat (when compared to the length of the tumor as, for instance, in the case of a bone tumor in a femur) initial colony. In…
We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…
The work analyzes a one-dimensional viscoelastic model of blood vessel growth under nonlinear friction with surroundings, and provides numerical simulations for various growing cases. For the nonlinear differential equations, two sufficient…
Angiogenesis is the formation of new blood vessels from pre-existing ones in response to chemical signals secreted by, for example, a wound or a tumour. In this paper, we propose a mesoscopic lattice-based model of angiogenesis, in which…
In this work, we investigate a fractional-order tumor growth model aimed at capturing memory effects and nonlocal temporal dynamics inherent to tumor evolution. The model is formulated using Caputo fractional derivatives and incorporates…
We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…
In this work, we study the Neumann initial boundary value problem for a three-component chemotaxis model in any dimensional bounded and smooth domains; this model is used to describe the branching of capillary sprouts during angiogenesis.…
In this paper we study a model describing the growth of necrotic tumors in different regimes of vascularisation. The tumor consists of a necrotic core of death cells and a surrounding nonnecrotic shell. The corresponding mathematical…
We provide a detailed numerical study of various issues pertaining to the dynamics of the Burgers equation perturbed by a weak dispersive term: blow-up in finite time versus global existence, nature of the blow-up, existence for "long"…
We study the spatial evolutionary dynamics of solid tumors as they obtain additional driver mutations. We start with a cancer clone that expands uniformly in three dimensions giving rise to a spherical shape. We assume that cell division…
In this article we deal with one-dimensional inverse problems concerning the Burgers equation and some related nonlinear systems (involving heat effects and/or variable density). In these problems, the goal is to find the size of the…
A recent conceptual model of tumor-driven angiogenesis including branching, elongation, and anastomosis of blood vessels captures some of the intrinsic multiscale structures of this complex system, yet allowing to extract a deterministic…
A fractional time derivative is introduced into the Burger's equation to model losses of nonlinear waves. This term amounts to a time convolution product, which greatly penalizes the numerical modeling. A diffusive representation of the…
We study the paralinearised weakly dispersive Burgers type equation: $$\partial_t u+T_u \partial_xu+\partial_x |D|^{\alpha-1}u=0,\ \alpha \in ]1,2[,$$ which contains the main non linear "worst interaction" terms, that is low-high…
We study a system of particles in a two-dimensional geometry that move according to a reinforced random walk with transition probabilities dependent on the solutions of reaction-diffusion equations for the underlying fields. A birth process…
We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries. Although many mathematical models have been developed to describe the…
A mathematical analysis of local and nonlocal phase-field models of tumor growth is presented that includes time-dependent Darcy-Forchheimer-Brinkman models of convective velocity fields and models of long-range cell interactions. A…
We consider the fractional Burgers equation $ \Delta^{\alpha/2} u + b\cdot \nabla (u|u|^{(\alpha-1)/\beta})$ on ${\mathbf R}^d$, $d\geq2$, with {$\alpha \in (1,2)$ and} $\beta>1$ and prove the existence of a solution for a large class of…