Related papers: A nonlocal model describing tumor angiogenesis
We propose a diffuse interface model to describe tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a…
I previously used Burgers' equation to introduce a new method of numerical discretisation of \pde{}s. The analysis is based upon centre manifold theory so we are assured that the discretisation accurately models all the processes and their…
We consider the problem of the long time dynamics for a diffuse interface model for tumor growth. The model describes the growth of a tumor surrounded by host tissues in the presence of a nutrient and consists in a Cahn-Hilliard-type…
We consider a local Cahn-Hilliard-type model for tumor growth as well as a nonlocal model where, compared to the local system, the Laplacian in the equation for the chemical potential is replaced by a nonlocal operator. The latter is…
We examine a lattice model of tumor growth where survival of tumor cells depends on the supplied nutrients. When such a supply is random, the extinction of tumors belongs to the directed percolation universality class. However, when the…
We construct a class of infinite mass functions for which solutions of the viscous Burgers equation decay at a better rate than solution of the heat equation for initial data in this class. In other words, we show an enhanced dissipation…
We study a non-local variant of a diffuse interface model proposed by Hawkins--Darrud et al. (2012) for tumour growth in the presence of a chemical species acting as nutrient. The system consists of a Cahn--Hilliard equation coupled to a…
We present a mathematical analysis of a mixed ODE-PDE model describing the spatial distribution and temporal evolution of tumor and normal cells within a tissue subject to the effects of a chemotherapeutic drug. The model assumes that the…
In this paper, we explore a nonlocal inviscid Burgers equation. Fixing a parameter $h$, we prove existence and uniqueness of the local solution of the equation $\InviscidBurgersNonlocal{u}$ with periodic initial condition. We also explore…
We prove finite time blowup of the Burgers-Hilbert equation. We construct smooth initial data with finite $H^5$-norm such that the $L^\infty$-norm of the spacial derivative of the solution blows up. The blowup is an asymptotic self-similar…
We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the…
In this paper we study a mathematical model for the growth of nonnecrotic solid tumor. The tumor is assumed to be radially symmetric and its radius R(t) is an unknown function of time t as tumor growth, and the model is in the form of a…
In the present work, we develop a comprehensive and rigorous analytical framework for a non-local phase-field model that describes tumour growth dynamics. The model is derived by coupling a non-local Cahn-Hilliard equation with a parabolic…
We propose a mathematical model for tumor invasion supported by angiogenesis and interactions with the surrounding tissue. For the model deduction we employ a multiscale approach starting from lower scales and obtaining by an informal…
Due to over-metabolism, the tumour cells become hypoxic. To overcome this situation tumour cells secret several chemical substrates to attract nearby blood vessels towards it (angiogenesis). Transition from avascular to vascular tumour is…
Front propagation described by Huygens' principle is a fundamental mechanism of spatial spreading of a property or an effect, occurring in optics, acoustics, ecology and combustion. If the local front speed varies randomly due to…
In this study, we model avascular tumour growth in epithelial tissue. This can help us to get a macroscopic view of the interaction between the tumour with its surrounding microenvironment and the physical changes within the tumour…
Over the past decades, nonlocal models have been widely used to describe aggregation phenomena in biology, physics, engineering, and the social sciences. These are often derived as mean-field limits of attraction-repulsion agent-based…
We consider the fractional unforced Burgers equation in the one-dimensional space-periodic setting: $$\partial u/\partial t+(f(u))_x +\nu \Lambda^{\alpha} u= 0, t \geq 0,\ \mathbb{x} \in \mathbb{T}^d=(\mathbb{R}/\mathbb{Z})^d.$$ Here $f$ is…
Employing a novel two-dimensional computational model we have simulated the feedback between angiogenesis and tumor growth dynamics. Analyzing vessel formation and elongation towards the concentration gradient of the tumor-derived…