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Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

Machine Learning · Statistics 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

Motion Cueing Algorithms (MCAs) encode the movement of simulated vehicles into movement that can be reproduced with a motion simulator to provide a realistic driving experience within the capabilities of the machine. This paper introduces a…

Robotics · Computer Science 2025-04-11 Camilo Gonzalez Arango , Houshyar Asadi , Mohammad Reza Chalak Qazani , Chee Peng Lim

Artificial Intelligence and Machine Learning (AI/ML) models used in clinical settings are increasingly deployed to support clinical decision-making. However, when training data become stale due to changes in demographics, environment, or…

Artificial Intelligence · Computer Science 2026-04-28 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

This work extends our prior work on the distributed nonlinear model predictive control (NMPC) for navigating a robot fleet following a certain flocking behavior in unknown obstructed environments with a more realistic local obstacle…

Robotics · Computer Science 2025-07-15 Nuthasith Gerdpratoom , Kaoru Yamamoto

Nonlinear model predictive control (NMPC) has gained widespread use in many applications. Its formulation traditionally involves repetitively solving a nonlinear constrained optimization problem online. In this paper, we investigate NMPC…

Systems and Control · Electrical Eng. & Systems 2022-05-11 Iman Askari , Shen Zeng , Huazhen Fang

A novel decomposition scheme to solve parametric non-convex programs as they arise in Nonlinear Model Predictive Control (NMPC) is presented. It consists of a fixed number of alternating proximal gradient steps and a dual update per time…

Optimization and Control · Mathematics 2014-12-25 Jean-Hubert Hours , Colin N. Jones

Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Kezhi Li , John Daniels , Chengyuan Liu , Pau Herrero , Pantelis Georgiou

This paper compares the performance of a decentralized proportional-integral-derivative (PID) controller, a linear model predictive controller (LMPC), and a nonlinear model predictive controller (NMPC) applied to a quadruple tank system…

Digital twin technologies help practitioners simulate, monitor, and predict undesirable outcomes in-silico, while avoiding the cost and risks of conducting live simulation exercises. Virtual reality (VR) based digital twin technologies are…

Machine Learning · Computer Science 2025-04-01 Chathika Gunaratne , Mason Stott , Debraj De , Gautam Malviya Thakur , Chris Young

Background: Predictive modeling is a key component of solutions to many healthcare problems. Among all predictive modeling approaches, machine learning methods often achieve the highest prediction accuracy, but suffer from a long-standing…

Machine Learning · Computer Science 2018-12-10 Gang Luo

Designing controllers under uncertainty requires balancing the need to explore system dynamics with the requirement to maintain reliable control performance. Dual control addresses this challenge by selecting actions that both regulate the…

Optimization and Control · Mathematics 2025-12-18 Mohammad Mahmoudi Filabadi , Guillaume Crevecoeur , Tom Lefebvre

This paper presents an auto-tuning framework for torque-based Nonlinear Model Predictive Control (nMPC), where the MPC serves as a real-time controller for optimal joint torque commands. The MPC parameters, including cost function weights…

Robotics · Computer Science 2025-12-04 Gabriele Fadini , Deepak Ingole , Tong Duy Son , Alisa Rupenyan

A fuel cell system must output a steady voltage as a power source in practical use. A neural network (NN) based model predictive control (MPC) approach is developed in this work to regulate the fuel cell output voltage with safety…

Systems and Control · Electrical Eng. & Systems 2024-06-26 Xiufei Li , Miao Yang , Yuanxin Qi , Miao Zhang

Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, several artificial pancreas systems…

Neural and Evolutionary Computing · Computer Science 2023-05-09 J. Ignacio Hidalgo , J. Manuel Colmenar , José L. Risco-Martín , Alfredo Cuesta-Infante , Esther Maqueda , Marta Botella , José Antonio Rubio

Diabetes is a prevalent chronic condition that compromises the health of millions of people worldwide. Minimally invasive methods are needed to prevent and control diabetes but most devices for measuring glucose levels are invasive and not…

In this paper, a multi-model predictive control approach is used to automate the co-administration of propofol and remifentanil from bispectral index measurement during general anesthesia. To handle the parameter uncertainties in the…

Systems and Control · Electrical Eng. & Systems 2023-09-18 Bob Aubouin-Pairault , Mirko Fiacchini , Thao Dang

This paper is about a real-time model predictive control (MPC) algorithm for large-scale, structured linear systems with polytopic state and control constraints. The proposed controller receives the current state measurement as an input and…

Optimization and Control · Mathematics 2019-03-19 Yuning Jiang , Juraj Oravec , Boris Houska , Michal Kvasnica

Control of nonlinear systems with high levels of uncertainty is practically relevant and theoretically challenging. This paper presents a numerical investigation of an adaptive nonlinear model predictive control (MPC) technique that relies…

Systems and Control · Electrical Eng. & Systems 2026-02-06 Rami Abdulelah Alhazmi , Achinth Suresh Babu , Syed Aseem Ul Islam , Dennis S. Bernstein

In this paper, adaptive neural control (ANC) is investigated for a class of strict-feedback nonlinear stochastic systems with unknown parameters, unknown nonlinear functions and stochastic disturbances. The new controller of adaptive neural…

Systems and Control · Computer Science 2017-02-08 Chao-Yang Chena , Wei-Hua Gui , Zhi-Hong Guan , Ru-Liang Wang , Shao-Wu Zhou

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

Quantitative Methods · Quantitative Biology 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart
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