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This paper proposes a new sampling-based nonlinear model predictive control (MPC) algorithm, with a bound on complexity quadratic in the prediction horizon N and linear in the number of samples. The idea of the proposed algorithm is to use…

Systems and Control · Computer Science 2017-01-13 R. V. Bobiti , M. Lazar

In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…

Control of non-condensing non-ideal-gas power cycles is challenging because their output power dynamics depend on complex system interactions, non-ideal-gas effects complicate turbomachinery behavior, and state constraints must be…

Systems and Control · Electrical Eng. & Systems 2021-08-30 Viv Bone , Michael Kearney , Ingo Jahn

Diabetes is a civilization chronic disease characterized by a constant elevated concentration of glucose in the blood. Many processes are involved in the glucose regulation, and their interactions are very complex. To better understand…

Cell Behavior · Quantitative Biology 2025-06-02 Kamila Barylska , Franck Delaplace , Anna Gogolińska , Ewa Pańkowska

This paper presents an adaptive tracking model predictive control (MPC) scheme to control unknown nonlinear systems based on an adaptively estimated linear model. The model is determined based on linear system identification using a moving…

Systems and Control · Electrical Eng. & Systems 2024-05-17 Tatiana Strelnikova , Johannes Köhler , Julian Berberich

Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or…

Computers and Society · Computer Science 2019-08-29 Sebastian Spänig , Agnes Emberger-Klein , Jan-Peter Sowa , Ali Canbay , Klaus Menrad , Dominik Heider

Diabetes mellitus (DM) is a global health issue of significance that must be diagnosed as early as possible and managed well. This study presents a framework for diabetes prediction using Machine Learning (ML) models, complemented with…

Machine Learning · Computer Science 2025-02-13 Pir Bakhsh Khokhar , Viviana Pentangelo , Fabio Palomba , Carmine Gravino

The practical deployment of nonlinear model predictive control (NMPC) is often limited by online computation: solving a nonlinear program at high control rates can be expensive on embedded hardware, especially when models are complex or…

Machine Learning · Computer Science 2026-03-26 Mihaela-Larisa Clement , Mónika Farsang , Agnes Poks , Johannes Edelmann , Manfred Plöchl , Radu Grosu , Ezio Bartocci

This paper introduces a novel nonlinear model predictive control (NMPC) framework that incorporates a lifting technique to enhance control performance for nonlinear systems. While the lifting technique has been widely employed in linear…

Systems and Control · Electrical Eng. & Systems 2025-07-15 Nuthasith Gerdpratoom , Fumiya Matsuzaki , Yutaka Yamamoto , Kaoru Yamamoto

The classification of diabetes and prediabetes by static glucose thresholds obscures the pathophysiological dysglycemia heterogeneity, primarily driven by insulin resistance (IR), beta-cell dysfunction, and incretin deficiency. This review…

Machine Learning · Computer Science 2025-11-07 Ahmed A. Metwally , Heyjun Park , Yue Wu , Tracey McLaughlin , Michael P. Snyder

This paper presents a control algorithm for creating an artificial pancreas for type 1 diabetes, factoring in input saturation for a practical application. By utilizing the parallel distributed compensation and Takagi-Sugeno Fuzzy model, we…

Systems and Control · Electrical Eng. & Systems 2024-08-21 Mohammadreza Ganji , Mahdi Pourgholi

This paper proposes an algorithm that combines Fast Moving Horizon Parameter Estimation and Model Predictive Control subject to an observability constraint designed to ensure a lower bound on the performance of the parameter estimator.…

Optimization and Control · Mathematics 2023-03-27 Emilien Flayac , Girish Nair , Iman Shames

Accurately estimating parameters of physiological models is essential to achieving reliable digital twins. For Type 1 Diabetes, this is particularly challenging due to the complexity of glucose-insulin interactions. Traditional methods…

Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to…

Quantitative Methods · Quantitative Biology 2011-01-05 Martin Berglund , Mikael Sunnåker , Martin Adiels , Mats Jirstrand , Bernt Wennberg

AI procedures joined with wearable gadgets can convey exact transient blood glucose level forecast models. Also, such models can learn customized glucose-insulin elements dependent on the sensor information gathered by observing a few parts…

Machine Learning · Computer Science 2021-01-22 Ignacio Rodriguez

In this study, we present a non-invasive glucose prediction system that integrates Near-Infrared (NIR) spectroscopy and millimeter-wave (mm-wave) sensing. We employ a Mixed Linear Model (MixedLM) to analyze the association between mm-wave…

Machine Learning · Computer Science 2024-09-12 Yuyang Sun , Panagiotis Kosmas

We present an approach for accelerating nonlinear model predictive control. If the current optimal input signal is saturated, also the optimal signals in subsequent time steps often are. We propose to use the open-loop optimal input signals…

Optimization and Control · Mathematics 2020-09-15 Raphael Dyrska , Ruth Mitze , Martin Mönnigmann

We present a dual Model Predictive Control (MPC) framework for the simultaneous identification and control of quasi-Linear Parameter Varying (qLPV) systems. The framework is composed of an online estimator for the states and parameters of…

Systems and Control · Electrical Eng. & Systems 2026-04-01 Sampath Kumar Mulagaleti , Alberto Bemporad

A variety of oscillations are observed in pancreatic islets.We establish a model, incorporating two oscillatory systems of different time scales: One is the well-known bursting model in pancreatic beta-cells and the other is the…

Cell Behavior · Quantitative Biology 2009-11-11 H. Kang , J. Jo , H. J. Kim , M. Y. Choi , S. W. Rhee , D. S. Koh

The 3rd AI Olympics with RealAIGym competition poses the challenge of developing a global policy that can swing up and stabilize an underactuated 2-link system Acrobot and/or Pendubot from any configuration in the state space. This paper…

Systems and Control · Electrical Eng. & Systems 2025-04-09 Blanka Burchard , Franek Stark
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