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We investigate stochastic extinction in an epidemic model and the impact of random vaccinations in large populations formulated in terms of an optimal escape path. We find that different random vaccination strategies can have widely…

Biological Physics · Physics 2007-11-12 Alexandra S. Landsman , Ira B. Schwartz

Contacts between individuals serve as pathways where infections may propagate. These contact patterns can be represented by network structures. Static structures have been the common modeling paradigm but recent results suggest that…

Populations and Evolution · Quantitative Biology 2012-04-25 Luis Enrique Correa Rocha , Adeline Decuyper , Vincent D Blondel

After the introduction of drastic containment measures aimed at stopping the epidemic contagion from SARS-CoV2, many governments have adopted a strategy based on a periodic relaxation of such measures in the face of a severe economic crisis…

Populations and Evolution · Quantitative Biology 2021-06-10 Giacomo Albi , Lorenzo Pareschi , Mattia Zanella

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

In regard to infectious diseases socioeconomic determinants are strongly associated with differential exposure and susceptibility however they are seldom accounted for by standard compartmental infectious disease models. These associations…

Applications · Statistics 2022-11-28 Alison C Hale , Jonathan M Read , Christopher P Jewell

These notes describe stochastic epidemics in a homogenous community. Our main concern is stochastic compartmental models (i.e. models where each individual belongs to a compartment, which stands for its status regarding the epidemic under…

Probability · Mathematics 2020-02-06 Tom Britton , Etienne Pardoux

A key scientific challenge during the outbreak of novel infectious diseases is to predict how the course of the epidemic changes under different countermeasures that limit interaction in the population. Most epidemiological models do not…

Physics and Society · Physics 2023-01-25 Mansi Sood , Anirudh Sridhar , Rashad Eletreby , Chai Wah Wu , Simon A. Levin , H. Vincent Poor , Osman Yagan

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

Populations and Evolution · Quantitative Biology 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

Populations and Evolution · Quantitative Biology 2026-05-14 Abhay Gupta , Nicholas W. Landry

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and…

This work describes a simple agent model for the spread of an epidemic outburst, with special emphasis on mobility and geographical considerations, which we characterize via statistical mechanics and numerical simulations. As the mobility…

Statistical Mechanics · Physics 2021-09-30 Óscar Toledano , Begoña Mula , Silvia N. Santalla , Javier Rodríguez-Laguna , Óscar Gálvez

This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented. The purpose of modelling is illustrated by…

Probability · Mathematics 2009-11-05 Tom Britton

We study how the interplay between the memory immune response and pathogen mutation affects epidemic dynamics in two related models. The first explicitly models pathogen mutation and individual memory immune responses, with contacted…

Chaotic Dynamics · Physics 2009-11-07 Michelle Girvan , Duncan S. Callaway , M. E. J. Newman , Steven H. Strogatz

We introduce a theoretical framework that highlights the impact of physical distancing variables such as human mobility and physical proximity on the evolution of epidemics and, crucially, on the reproduction number. In particular, in…

Physics and Society · Physics 2022-01-31 Fabio Vanni , David Lambert , Luigi Palatella

Accurate estimates of the reproduction ratio are crucial to project infectious disease epidemic evolution and guide public health response. Here, we prove that estimates of the reproduction ratio based on inference from surveillance data…

Physics and Society · Physics 2025-01-08 Piero Birello , Michele Re Fiorentin , Boxuan Wang , Vittoria Colizza , Eugenio Valdano

With the prevalence of COVID-19, the modeling of epidemic propagation and its analyses have played a significant role in controlling epidemics. However, individual behaviors, in particular the self-protection and migration, which have a…

Social and Information Networks · Computer Science 2025-11-25 Yuhan Li , Ziyan Zeng , Minyu Feng , Jürgen Kurths

During epidemic outbreaks, information dissemination enhances individual protection, while social institutions influence the transmission through measures like government interventions, media campaigns, and hospital resource allocation.…

Physics and Society · Physics 2025-06-03 Mengshou Wang , Liangrong Peng , Baoguo Jia , Liu Hong

Different countries -- and sometimes different regions within the same countries -- have adopted different strategies in trying to contain the ongoing COVID-19 epidemic; these mix in variable parts social confinement, early detection and…

Populations and Evolution · Quantitative Biology 2020-07-17 Giuseppe Gaeta

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

Physics and Society · Physics 2021-05-07 Bo Li , David Saad

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

Quantitative Methods · Quantitative Biology 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss
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