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Sexually transmitted infections (STIs) continue to present a complex and costly challenge to public health programs. The preferences and social dynamics of a population can have a large impact on the course of an outbreak as well as the…

Populations and Evolution · Quantitative Biology 2015-06-30 Michael A. L. Hayashi , Marisa C. Eisenberg

Heterogeneity of population is a key factor in modeling the transmission of disease among the population and has huge impact on the outcome of the transmission. In order to investigate the decision making process in the heterogeneous mixing…

Populations and Evolution · Quantitative Biology 2024-03-01 Fan Bai , Qianyu Chen , Yizhuo Xu

Networks of person-person contacts form the substrate along which infectious diseases spread. Most network-based studies of the spread focus on the impact of variations in degree (the number of contacts an individual has). However, other…

Quantitative Methods · Quantitative Biology 2008-12-15 Joel C. Miller

It is well known that behavioral changes in contact patterns may significantly affect the spread of an epidemic outbreak. Here we focus on simple endemic models for recurrent epidemics, by modelling the social contact rate as a function of…

Populations and Evolution · Quantitative Biology 2013-09-16 Alberto d'Onofrio , Piero Manfredi

The generation interval is the time between the infection time of an infected person and the infection time of his or her infector. Probability density functions for generation intervals have been an important input for epidemic models and…

Quantitative Methods · Quantitative Biology 2023-10-24 Eben Kenah , Marc Lipsitch , James M. Robins

Major advances in public health have resulted from disease prevention. However, prevention of a new infectious disease by vaccination or pharmaceuticals is made difficult by the slow process of vaccine and drug development. We propose an…

Populations and Evolution · Quantitative Biology 2021-04-15 Jussi Taipale , Ioannis Kontoyiannis , Sten Linnarsson

Social contact studies, investigating social contact patterns in a population sample, have been an important contribution for epidemic models to better fit real life epidemics. A contact matrix $M$, having the \emph{mean} number of contacts…

Populations and Evolution · Quantitative Biology 2024-08-15 Tom Britton , Frank Ball

Epidemic modelling on complex networks has been studied intensively all the time. The majority of relative research assumes that the time scale of the underlying network evolution is much larger compared to the propagation dynamics on it,…

Physics and Society · Physics 2026-04-14 Minyu Feng , Yuhan Li , Jürgen Kurths

Immune events such as infection, vaccination, and a combination of the two result in distinct time-dependent antibody responses in affected individuals. These responses and event prevalences combine non-trivially to govern antibody levels…

Populations and Evolution · Quantitative Biology 2024-04-16 Prajakta Bedekar , Rayanne A. Luke , Anthony J. Kearsley

The rapid transmission of the highly contagious novel coronavirus has been represented through several data-guided approaches across targeted geographies, in an attempt to understand when the pandemic will be under control and imposed…

Populations and Evolution · Quantitative Biology 2020-05-05 Joydeep Munshi , Indranil Roy , Ganesh Balasubramanian

Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

Populations and Evolution · Quantitative Biology 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

The duration of the infectious period is a crucial determinant of the ability of an infectious disease to spread. We consider an epidemic model that is network based and non-Markovian, containing classic Kermack-McKendrick, pairwise,…

Populations and Evolution · Quantitative Biology 2018-05-25 Robert R. Wilkinson , Kieran J. Sharkey

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

Populations and Evolution · Quantitative Biology 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a…

Physics and Society · Physics 2019-09-04 Liqun Lu , Yanfeng Ouyang

Epidemic models study the spread of an undesired agent through a population, be it infectious diseases through a country, misinformation in online social media, or pests infesting a region. In combating these epidemics, we rely neither on…

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

Models of biological processes are often subject to different sources of noise. Developing an understanding of the combined effects of different types of uncertainty is an open challenge. In this paper, we study a variant of the…

Populations and Evolution · Quantitative Biology 2018-03-28 Francisco Herrerías-Azcué , Tobias Galla

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

This paper uses new and existing methods to study collective trends across countries throughout the pandemic, with a focus on the multivariate time series of reproduction numbers and vaccine proliferation. We begin with a time-varying…

Physics and Society · Physics 2023-10-16 Nick James , Max Menzies
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