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Related papers: Optimal Lockdown to Manage an Epidemic

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Policymakers commonly employ non-pharmaceutical interventions to manage the scale and severity of pandemics. Of non-pharmaceutical interventions, social distancing policies -- designed to reduce person-to-person pathogenic spread -- have…

Physics and Society · Physics 2021-03-23 Demetris Avraam , Nick Obradovich , Niccoló Pescetelli , Manuel Cebrian , Alex Rutherford

We study first order necessary conditions for an optimal control problem of a Susceptible-Infected-Recovered (SIR) model with limitations on the duration of the quarantine. The control is done by means of the reproduction number, i.e., the…

COVID-19 is a global epidemic. Till now, there is no remedy for this epidemic. However, isolation and social distancing are seemed to be effective preventive measures to control this pandemic. Therefore, in this paper, an optimization…

Non-pharmaceutical interventions (NPIs) are crucial for controlling pandemics, but existing research often overlooks the heterogeneity of individual behavior, which can lead to inaccurate evaluations of the effectiveness of strategies. In…

Physics and Society · Physics 2026-03-09 Xihan Zhang , Yuqing Liu , Chen Zhao , Guijun Li

In the absence of neither an effective treatment or vaccine and with an incomplete understanding of the epidemiological cycle, Govt. has implemented a nationwide lockdown to reduce COVID-19 transmission in India. To study the effect of…

Populations and Evolution · Quantitative Biology 2020-08-26 Tridip Sardar , Sk Shahid Nadim , Sourav Rana , Joydev Chattopadhyay

We study the problem of estimating the parameters (i.e., infection rate and recovery rate) governing the spread of epidemics in networks. Such parameters are typically estimated by measuring various characteristics (such as the number of…

Systems and Control · Electrical Eng. & Systems 2021-05-12 Lintao Ye , Philip E. Paré , Shreyas Sundaram

Mass public quarantining, colloquially known as a lock-down, is a non-pharmaceutical intervention to check spread of disease. This paper presents ESOP (Epidemiologically and Socio-economically Optimal Policies), a novel application of…

Populations and Evolution · Quantitative Biology 2020-06-16 Amit Chandak , Debojyoti Dey , Bhaskar Mukhoty , Purushottam Kar

The ongoing pandemic of coronavirus disease 2019-2020 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This pathogenic virus is able to spread asymptotically during its incubation stage through a…

Physics and Society · Physics 2020-08-14 Subhas Kumar Ghosh , Sachchit Ghosh , Sai Shanmukha Narumanchi

We present a control framework for stochastic compartmental models in epidemiology. In this framework, rather than directly controlling the stochastic system, we perform optimal control of an associated Fokker-Planck equation, with the goal…

Optimization and Control · Mathematics 2026-04-06 Christian Parkinson , Souvik Roy

We devise a theoretical model for the optimal dynamical control of an infectious disease whose diffusion is described by the SVIR compartmental model. The control is realized through implementing social rules to reduce the disease's spread,…

Optimization and Control · Mathematics 2022-08-10 Alessandro Ramponi , Maria Elisabetta Tessitore

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

Without vaccines and treatments, societies must rely on non-pharmaceutical intervention strategies to control the spread of emerging diseases such as COVID-19. Though complete lockdown is epidemiologically effective, because it eliminates…

Populations and Evolution · Quantitative Biology 2021-01-08 Jason Hindes , Simone Bianco , Ira B. Schwartz

The emergence of an epidemic evokes the need to monitor its spread and assess and validate any mitigation measures enacted by governments and administrative bodies in real time. We present here a method to observe and quantify this spread…

Populations and Evolution · Quantitative Biology 2024-11-06 Justin Trujillo , Valerica Raicu

Severe infectious diseases such as the novel coronavirus (COVID-19) pose a huge threat to public health. Stringent control measures, such as school closures and stay-at-home orders, while having significant effects, also bring huge economic…

Machine Learning · Computer Science 2022-03-01 Runzhe Wan , Xinyu Zhang , Rui Song

Coronavirus outbreak is one of the most challenging pandemics for the entire human population of the planet Earth. Techniques such as the isolation of infected persons and maintaining social distancing are the only preventive measures…

Social and Information Networks · Computer Science 2020-09-01 Rahul Mishra , Hari Prabhat Gupta , Tanima Dutta

Balancing common disease treatment and epidemic control is a key objective of medical supplies procurement in hospitals during a pandemic such as COVID-19. This problem can be formulated as a bi-objective optimization problem for…

Neural and Evolutionary Computing · Computer Science 2020-08-04 Yu-Jun Zheng , Xin Chen , Tie-Er Gan , Min-Xia Zhang , Wei-Guo Sheng , Ling Wang

The aim of this paper is to provide a rigorous mathematical analysis of an optimal control problem with SIR dynamics. The main feature of our study is the presence of state constraints (related to intensive care units ICU capacity) and…

Optimization and Control · Mathematics 2021-08-25 Florin Avram , Lorenzo Freddi , Dan Goreac

In this paper, we develop a robust economic model predictive controller for the containment of stochastic Susceptible-Exposed-Infected-Vigilant (SEIV) epidemic processes which drives the process to extinction quickly, while minimizing the…

Optimization and Control · Mathematics 2019-05-14 Nicholas J. Watkins , Cameron Nowzari , George J. Pappas

During an infectious disease outbreak, policymakers must balance medical costs with social and economic burdens and seek interventions that minimize both. To support this decision-making process, we developed a framework that integrates…

Optimization and Control · Mathematics 2026-04-03 Jongmin Lee , Renier Mendoza , Victoria May P. Mendoza , Eunok Jung

In the wake of COVID-19, every government huddles to find the best interventions that will reduce the number of infection cases while minimizing the economic impact. However, with many intervention policies available, how should one decide…

Optimization and Control · Mathematics 2021-04-19 Chang Liu , Akshay Budhkar