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Glioblastoma is the most malignant type of central nervous system tumor with GBM subtypes cleaved based on molecular level gene alterations. These alterations are also happened to affect the histology. Thus, it can cause visible changes in…

Quantitative Methods · Quantitative Biology 2020-10-28 Navodini Wijethilake , Mobarakol Islam , Dulani Meedeniya , Charith Chitraranjan , Indika Perera , Hongliang Ren

Background and Objective: Non-invasively predicting the risk of cancer metastasis before surgery plays an essential role in determining optimal treatment methods for cancer patients (including who can benefit from neoadjuvant chemotherapy).…

Glioblastoma Multiforme (GBM) is a highly aggressive brain tumour with limited therapeutic options and poor prognosis. This study presents a mathematical framework to investigate the efficacy of immunotherapy strategies based on cytotoxic…

Populations and Evolution · Quantitative Biology 2025-12-23 Francesca Ballatore , Lorenzo Scolaris , Chiara Giverso

Glioblastoma is a highly aggressive and malignant brain tumor type that requires early diagnosis and prompt intervention. Due to its heterogeneity in appearance, developing automated detection approaches is challenging. To address this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Ziya Ata Yazıcı , İlkay Öksüz , Hazım Kemal Ekenel

In this work, we aim to predict the survival time (ST) of glioblastoma (GBM) patients undergoing different treatments based on preoperative magnetic resonance (MR) scans. The personalized and precise treatment planning can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Xiaofeng Liu , Nadya Shusharina , Helen A Shih , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

Glioblastoma multiforme (GBM) is a fast-growing and highly invasive brain tumour, it tends to occur in adults between the ages of 45 and 70 and it accounts for 52 percent of all primary brain tumours. Usually, GBMs are detected by magnetic…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Matteo Rucco , Lorenzo Falsetti , Giovanna Viticchi

The RSNA-MICCAI brain tumor radiogenomic classification challenge aimed to predict MGMT biomarker status in glioblastoma through binary classification on Multi parameter mpMRI scans: T1w, T1wCE, T2w and FLAIR. The dataset is splitted into…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Amr Mohamed , Mahmoud Rabea , Aya Sameh , Ehab Kamal

Neuroblastoma is one of the most common cancers in infants, and the initial diagnosis of this disease is difficult. At present, the MYCN gene amplification (MNA) status is detected by invasive pathological examination of tumor samples. This…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 Zihan Zhang , Xiang Xiang , Xuehua Peng , Jianbo Shao

Neuroblastoma (NB), a leading cause of childhood cancer mortality, exhibits significant histopathological variability, necessitating precise subtyping for accurate prognosis and treatment. Traditional diagnostic methods rely on subjective…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Huangwei Chen , Yifei Chen , Zhenyu Yan , Mingyang Ding , Chenlei Li , Zhu Zhu , Feiwei Qin

Gliomas are the most common primary brain tumors, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Volumetric assessment of tumor volume with manual…

Glioblastoma is the most common primary adult brain tumor, with a grim prognosis - median survival of 12-18 months following treatment, and 4 months otherwise. Glioblastoma is widely infiltrative in the cerebral hemispheres and well-defined…

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

Brain tumor is a life-threatening problem and hampers the normal functioning of the human body. The average five-year relative survival rate for malignant brain tumors is 35.6 percent. For proper diagnosis and efficient treatment planning,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Vidhyapriya Ranganathan , Celshiya Udaiyar , Jaisree Jayanth , Meghaa P , Srija B , Uthra S

The accurate prognosis of Glioblastoma Multiforme (GBM) plays an essential role in planning correlated surgeries and treatments. The conventional models of survival prediction rely on radiomic features using magnetic resonance imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-05-03 Mobarakol Islam , Navodini Wijethilake , Hongliang Ren

Medulloblastoma (MB) is the most common malignant brain tumor in childhood. The diagnosis is generally based on the microscopic evaluation of histopathological tissue slides. However, visual-only assessment of histopathological patterns is…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Marcel Bengs , Michael Bockmayr , Ulrich Schüller , Alexander Schlaefer

Glioblastoma recurrence is largely driven by diffuse infiltration beyond radiologically visible tumor margins, yet standard radiotherapy, the mainstay of glioblastoma treatment, relies on uniform expansions that ignore patient-specific…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 L. Zimmer , J. Weidner , M. Balcerak , F. Kofler , M. Krupa , I. Ezhov , S. Cepeda , R. Zhang , J. Lowengrub , B. Menze , B. Wiestler

We proposed a fully automatic workflow for glioblastoma (GBM) survival prediction using deep learning (DL) methods. 285 glioma (210 GBM, 75 low-grade glioma) patients were included. 163 of the GBM patients had overall survival (OS) data.…

Medical Physics · Physics 2021-07-07 Jie Fu , Kamal Singhrao , Xinran Zhong , Yu Gao , Sharon Qi , Yingli Yang , Dan Ruan , John H Lewis

Glioma constitutes 80% of malignant primary brain tumors and is usually classified as HGG and LGG. The LGG tumors are less aggressive, with slower growth rate as compared to HGG, and are responsive to therapy. Tumor biopsy being challenging…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Subhashis Banerjee , Sushmita Mitra , Francesco Masulli , Stefano Rovetta

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

Applications · Statistics 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury