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Glioblastoma is a highly invasive brain tumor, whose cells infiltrate surrounding normal brain tissue beyond the lesion outlines visible in the current medical scans. These infiltrative cells are treated mainly by radiotherapy. Existing…

Glioma is the most deadly brain tumor with high mortality. Treatment planning by human experts depends on the proper diagnosis of physical symptoms along with Magnetic Resonance(MR) image analysis. Highly variability of a brain tumor in…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Rupal Agravat , Mehul S Raval

Gender disparities in health outcomes have garnered significant attention, prompting investigations into their underlying causes. Glioblastoma (GBM), a devastating and highly aggressive form of brain tumor, serves as a case for such…

Applications · Statistics 2023-08-09 Solomon Eshun

Machine learning (ML) is a branch of Artificial Intelligence (AI) where computers analyze data and find patterns in the data. The study focuses on the detection of metastatic cancer using ML. Metastatic cancer is the point where the cancer…

Artificial Intelligence · Computer Science 2023-09-20 Bliss Singhal , Fnu Pooja

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Juexin Zhang , Qifeng Zhong , Ying Weng , Ke Chen

Automatic detection of brain neoplasm in Magnetic Resonance Imaging (MRI) is gaining importance in many medical diagnostic applications. This report presents two improvements for brain neoplasm detection in MRI data: an advanced…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Nilanjan Sinhababu , Monalisa Sarma , Debasis Samanta

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

Machine Learning · Computer Science 2026-02-13 Ankita Paul , Wenyi Wang

Glioblastoma (GBM) is a highly morbid and lethal disease with poor prognosis. Their emergent properties such as cellular heterogeneity, therapy resistance, and self-renewal are largely attributed to the interactions between a subset of…

Other Quantitative Biology · Quantitative Biology 2021-10-11 Abicumaran Uthamacumaran

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Aim: To review how machine learning (ML) is applied to imaging biomarkers in neuro-oncology, in particular for diagnosis, prognosis, and treatment response monitoring. Materials and Methods: The PubMed and MEDLINE databases were searched…

Quantitative Methods · Quantitative Biology 2019-10-17 Thomas Booth , Matthew Williams , Aysha Luis , Jorge Cardoso , Ashkan Keyoumars , Haris Shuaib

Malignant gliomas (MGs), particularly glioblastoma, are among the most aggressive brain tumors, with limited treatment options and a poor prognosis. Maximal safe resection and the so-called Stupp protocol are the standard first-line…

Stereotactic radiotherapy (SRT) is one of the most important treatment for patients with brain metastases (BM). Conventionally, following SRT patients are monitored by serial imaging and receive salvage treatments in case of significant…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Philipp Sommer , Yixing Huang , Christoph Bert , Andreas Maier , Manuel Schmidt , Arnd Dörfler , Rainer Fietkau , Florian Putz

According to the World Health Organization (WHO), cancer is the second leading cause of death worldwide, responsible for over 9.5 million deaths in 2018 alone. Brain tumors count for one out of every four cancer deaths. Therefore, accurate…

Image and Video Processing · Electrical Eng. & Systems 2021-12-10 Zahra SobhaniNia , Nader Karimi , Pejman Khadivi , Roshank Roshandel , Shadrokh Samavi

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

Brain Metastases (BM) complicate 20-40% of cancer cases. BM lesions can present as punctate (1 mm) foci, requiring high-precision Magnetic Resonance Imaging (MRI) in order to prevent inadequate or delayed BM treatment. However, BM lesion…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Engin Dikici , John L. Ryu , Mutlu Demirer , Matthew Bigelow , Richard D. White , Wayne Slone , Barbaros Selnur Erdal , Luciano M. Prevedello

Brain tumors represent one of the most critical neurological conditions, where early and accurate diagnosis is directly correlated with patient survival rates. Manual interpretation of Magnetic Resonance Imaging (MRI) scans is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Chinedu Emmanuel Mbonu , Tochukwu Sunday Belonwu , Okwuchukwu Ejike Chukwuogo , Kenechukwu Sylvanus Anigbogu

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye