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In cancer research, leveraging patient-derived xenografts (PDXs) in pre-clinical experiments is a crucial approach for assessing innovative therapeutic strategies. Addressing the inherent variability in treatment response among and within…

Flexible and accurate noise characterization is crucial for the precise estimation of gravitational-wave parameters. We introduce a Bayesian method for estimating the power spectral density (PSD) of long, stationary time series, explicitly…

General Relativity and Quantum Cosmology · Physics 2026-03-26 Nazeela Aimen , Patricio Maturana-Russel , Avi Vajpeyi , Nelson Christensen , Renate Meyer

We propose a Bayesian framework for fine-tuning large diffusion models with a novel network structure called Bayesian Power Steering (BPS). We clarify the meaning behind adaptation from a \textit{large probability space} to a \textit{small…

Machine Learning · Computer Science 2024-06-07 Ding Huang , Ting Li , Jian Huang

Group sequential designs drive innovation in clinical, industrial, and corporate settings. Early stopping for failure in sequential designs conserves experimental resources, whereas early stopping for success accelerates access to improved…

Methodology · Statistics 2025-11-27 Luke Hagar , Shirin Golchi , Marina B. Klein

Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many researchers. We introduce PowerGPT, an AI-powered system…

The power prior and its variations have been proven to be a useful class of informative priors in Bayesian inference due to their flexibility in incorporating the historical information by raising the likelihood of the historical data to a…

Methodology · Statistics 2022-04-14 Zifei Han , Keying Ye , Min Wang

The use of Bayesian adaptive designs for randomised controlled trials has been hindered by the lack of software readily available to statisticians. We have developed a new software package (Bayesian Adaptive Trials Simulator Software -…

The power prior is a popular class of informative priors for incorporating information from historical data. It involves raising the likelihood for the historical data to a power, which acts as a discounting parameter. When the discounting…

Methodology · Statistics 2025-05-26 Yueqi Shen , Matthew A. Psioda , Luiz M. Carvalho , Joseph G. Ibrahim

Gaussian factor models have proven widely useful for parsimoniously characterizing dependence in multivariate data. There is a rich literature on their extension to mixed categorical and continuous variables, using latent Gaussian variables…

Methodology · Statistics 2013-01-14 Jared S. Murray , David B. Dunson , Lawrence Carin , Joseph E. Lucas

We present an R package bssm for Bayesian non-linear/non-Gaussian state space modelling. Unlike the existing packages, bssm allows for easy-to-use approximate inference based on Gaussian approximations such as the Laplace approximation and…

Computation · Statistics 2022-04-13 Jouni Helske , Matti Vihola

Simultaneously achieving parsimony and good predictive power in high dimensions is a main challenge in statistics. Non-local priors (NLPs) possess appealing properties for high-dimensional model choice, but their use for estimation has not…

Statistics Theory · Mathematics 2015-01-22 David Rossell , Donatello Telesca

In this paper we present BayesLDM, a system for Bayesian longitudinal data modeling consisting of a high-level modeling language with specific features for modeling complex multivariate time series data coupled with a compiler that can…

Large language models (LLMs) offer a scalable mechanism to elicit domain-informed prior information for high-dimensional variable selection. However, existing methods such as LLM-Lasso are sensitive to weight quality, with performance…

Machine Learning · Statistics 2026-05-25 Caleb Skinner , Yihan Guo , Meng Li

Most of applied statistics involves regression analysis of data. This paper presents a stand-alone and menu-driven software package, Bayesian Regression: Nonparametric and Parametric Models. Currently, this package gives the user a choice…

Computation · Statistics 2015-07-15 George Karabatsos

Stochastic Process Model has many applications in analysis of longitudinal biodemographic data. Such data contain various physiological variables (sometimes known as covariates). It also can potentially contain genetic information available…

Populations and Evolution · Quantitative Biology 2016-05-31 Ilya Zhbannikov , Konstantin Arbeev , Anatoliy Yashin

Gaussian Process (GP) emulators are widely used to approximate complex computer model behaviour across the input space. Motivated by the problem of coupling computer models, recently progress has been made in the theory of the analysis of…

Applications · Statistics 2022-04-20 Victoria Volodina , Nikki Sonenberg , Peter Challenor , Jim Q. Smith

The empirical Bayes normal means (EBNM) model is important to many areas of statistics, including (but not limited to) multiple testing, wavelet denoising, and gene expression analysis. There are several existing software packages that can…

Computation · Statistics 2024-04-02 Jason Willwerscheid , Peter Carbonetto , Matthew Stephens

Generalized linear models (GLMs) using a regression procedure to fit relationships between predictor and target variables are widely used in automobile insurance data. Here, in the process of ratemaking and in order to compute the premiums…

Applications · Statistics 2016-06-02 J. M. Pérez-Sánchez , E. Gómez-Déniz

One of the main approaches used to construct prior distributions for objective Bayes methods is the concept of random imaginary observations. Under this setup, the expected-posterior prior (EPP) offers several advantages, among which it has…

Methodology · Statistics 2020-10-09 Dimitris Fouskakis , Ioannis Ntzoufras

Interpretability is crucial for machine learning in many scenarios such as quantitative finance, banking, healthcare, etc. Symbolic regression (SR) is a classic interpretable machine learning method by bridging X and Y using mathematical…

Methodology · Statistics 2020-01-17 Ying Jin , Weilin Fu , Jian Kang , Jiadong Guo , Jian Guo