Related papers: Optimization of FLASH Proton Beams Using a Track-R…
Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deliver a highly conformal dose to the tumor while sparing…
A high peak current, flat longitudinal phase space electron beam is desirable for efficient x-ray free electron laser (FEL) radiation in next generation light sources. To attain such a beam requires the extensive design of the linear…
A novel dose calculation approach was designed based on the application of LSTM network that processes the 3D patient/phantom geometry as a sequence of 2D computed tomography input slices yielding a corresponding sequence of 2D slices that…
Background and Objective: Recent experimental studies using ultra-high dose rate radiation therapy (FLASH-RT) have shown improved normal tissue sparing and comparable tumor control compared to conventional dose rate RT. Pencil beam scanning…
We have developed a model for proton depth dose and lateral distributions based on Monte Carlo calculations (GEANT4) and an integration procedure of the Bethe-Bloch equation (BBE). The model accounts for the transport of primary and…
We have measured the total energy spread (99 persent energy spread) of the Booster beam at its injection energy of 400 MeV by three different methods - 1) creating a notch of about 40 nsec wide in the beam immediately after multiple turn…
Purpose: To measure dispersion of a clinical proton therapy beam. Methods and Materials: The proton center at our institution uses a Hitachi PROBEAT V synchrotron that delivers beams with energies ranging from 70 to 230 MeV to five…
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research.…
Purpose: Respiratory motion and the interplay effect cause the dose delivered to a patient with spot-scanned proton therapy to differ from the dose planned for during optimization. A new 4D robust optimization methodology was developed…
In this paper, we proposed a method to optimize adaptive proton FLASH therapy (ADP FLASH) using modularized pin ridge filters (pRFs) by recycling module pins from the initial plan while reducing pRF adjustments in adaptive FLASH planning.…
The purpose of this study is to determine whether organ sparing and target coverage can be simultaneously maintained for pencil beam scanning (PBS) proton therapy treatment of thoracic tumors in the presence of motion, stopping power…
$Objective$. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the…
Improving effective treatment plans in carbon ion therapy, especially for targeting radioresistant tumors located in deep seated regions while sparing normal tissues, depends on a precise and computationally efficient dose calculation…
As the second stage of the CEPC-SPPC project, SPPC (Super Proton-Proton Collider) aims at exploring new physics beyond the Standard Model. The key design goal for the SPPC accelerator complex is to reach 75 TeV in center of mass energy with…
We investigated the parameter optimization of ridge filter thickness using a Monte Carlo simulation for carbon ion therapy. For this study, a ridge filter was designed for the Spread-Out Bragg Peak (SOBP) by considering the relative…
Purpose: Accurate prediction of beam delivery time (BDT) is essential for operational efficiency, 4D dose calculations, and advanced proton therapy techniques. Despite its importance, no machine-specific BDT model exists for Mevion systems.…
Monte Carlo (MC) simulation is considered as the most accurate method for radiation dose calculations. Accuracy of a source model for a linear accelerator is critical for the overall dose calculation accuracy. In this paper, we presented an…
Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…
Proton beam radiotherapy stands at the forefront of precision cancer treatment, leveraging the unique physical interactions of proton beams with human tissue to deliver minimal dose upon entry and deposit the therapeutic dose precisely at…
Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose.…