Related papers: Optimization of FLASH Proton Beams Using a Track-R…
Multi-slat prompt-gamma camera is a promising tool for range monitoring during proton therapy. We report the results of a comprehensive simulation study analyzing the precision which is possible to reach with this camera in determination of…
The present work is devoted to develop a computational model using the Gate Monte Carlo software for the simulation of a 6MV photon beam given by Elekta Synergy Platform medical linear accelerator treatment head. The model includes the…
Commercial treatment planning systems for electron FLASH radiotherapy are unavailable, and the dosimetric precision required for ultra-high dose rate delivery makes Monte Carlo (MC) simulation the gold standard approach. This work…
The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…
Purpose: To quantitatively compare the dosimetric and biologic differences in treatment plans from flattened and flattening-filter-free (FFF) beam for three anatomic cancer sites. Methods and Materials: Treatment plans with static…
FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely,…
Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be…
Purpose: Highlight the distinctions, both in terms of concept and numerical values, of the various definitions that can be established for the dose rate in PBS proton therapy. Methods: In an in silico study, five definitions of the dose…
Background: Ultra-high dose rate proton therapy shows promise in tissue sparing by enhancing therapeutic ratio through the FLASH effect. In radiotherapy, accurate in vivo dosimetry is crucial for quality assurance, but remains challenging…
Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated…
Purpose: To evaluate the latent variance (LV) of TrueBeam photon phase-space files (PSF) for open 10x10$cm^2$ and small fields. Methods: BEAMnrc/DOSXYZnrc was used to transport particles from Varian phase-space files (PSFA) through the…
The high gradients potentially achievable in distributed-coupling C-band photoinjectors make them attractive for many high brightness applications. Here we discuss optimization results for a 1.6 cell C-band photoinjector with a 240 MV/m…
Purpose: To enhance an in-house graphic-processing-unit (GPU) accelerated virtual particle (VP)-based Monte Carlo (MC) proton dose engine (VPMC) to model aperture blocks in both dose calculation and optimization for pencil beam scanning…
Proton radiography is used for advanced hydrotesting as a new type radiography technology due to its powerful penetration capability and high detection efficiency. A new proton radiography terminal will be developed to radiograph static…
To achieve multi-Gb/s data rates in 6G optical wireless access networks based on narrow infrared (IR) laser beams, a high-speed receiver with two key specifications is needed: a sufficiently large aperture to collect the required optical…
We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…
The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…
Heavy ions have varying effects on the target. The most important factor in comparing this effect is Linear Energy Transfer (LET). Protons and carbons are heavy ions with high LET. Since these ions lose energy through collisions as they…
Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent replanning. Methods: PBSPT plans of 103 prostate cancer…
We present an optimization procedure for neutrino beams which could be produced at CERN and aimed to a set of seven possible underground sites in Europe with distances ranging from 130 km to 2300 km. Studies on the feasibility of a next…