Related papers: Optimization of FLASH Proton Beams Using a Track-R…
Purpose: To assess the effects of brain movements induced by heartbeat on dose distributions in synchrotron micro- and mini-beam radiaton therapy and to develop a model to help guide decisions and planning for future clinical trials.…
When treating moving tumors, the precise delivery of proton therapy by pencil beam scanning (PBS) is challenged by the interplay effect. Although several 4D-optimization methods have been proposed, what is the most beneficial motion…
Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…
Objective: While FLASH radiotherapy is recognized for short-term normal tissue sparing, its durability in late-responding organs remains uncertain, limiting clinical adoption. With its clinical importance and steep dose-response, the spinal…
Accurate proton dose calculation using Monte Carlo (MC) is computationally demanding in workflows like robust optimisation, adaptive replanning, and probabilistic inference, which require repeated evaluations. To address this, we develop a…
Treatment planning system calculations in inhomogeneous regions may present significant inaccuracies due to loss of electronic equilibrium. In this study, three different dose calculation algorithms, pencil beam, collapsed cone, and…
Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…
Background and purpose: To propose a novel machine learning-based method for reliable and accurate modeling of linac beam data applicable to the processes of linac commissioning and QA. Materials and methods: We hypothesize that the beam…
Purpose: The purpose of the present article is to propose a modified version of the D-shaped collimator used at the Univ. Hosp. of Essen for retinoblastoma treatment that reduces even further the irradiation field with the scope to reduce…
Purpose: To validate the accuracy of 4D Monte Carlo (4DMC) simulations to calculate dose deliveries to a deforming anatomy in the presence of realistic respiratory motion traces. A previously developed deformable lung phantom comprising an…
Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery of high doses to targets, we aim to develop a deep…
The Beam Dump Facility (BDF) project is a proposed general-purpose facility at CERN, dedicated to beam dump and fixed target experiments. In its initial phase, the facility is foreseen to be exploited by the Search for Hidden Particles…
Microdosimetry provides a superior characterization of the radiation field compared to conventional LET-based methodology, and for this reason it has become increasingly attractive for quality assurance in particle therapy. However, the…
The Proton Improvement Plan, Stage Two (PIP-II) is a program of upgrades proposed for the Fermilab injection complex, which central part is an 800 MeV, 2 mA CW SRF linac. A prototype of the PIP-II linac front end called PIP-II Injector Test…
Miniature Micro Aerial Vehicles (MAV) are very suitable for flying in indoor environments, but autonomous navigation is challenging due to their strict hardware limitations. This paper presents a highly efficient computer vision algorithm…
We recently built an analytical source model for GPU-based MC dose engine. In this paper, we present a sampling strategy to efficiently utilize this source model in GPU-based dose calculation. Our source model was based on a concept of…
Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…
A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…
This study develops and validates a patient-specific Monte Carlo (MC) dosimetry framework for propagation-based phase-contrast breast CT (BCT) at the Imaging and Medical Beamline (IMBL), ANSTO Australian Synchrotron, for accurate mean…
Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…