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Genetic association data from national biobanks and large-scale association studies have provided new prospects for understanding the genetic evolution of complex traits and diseases in humans. In turn, genomes from ancient human…

Populations and Evolution · Quantitative Biology 2021-08-06 Evan K. Irving-Pease , Rasa Muktupavela , Michael Dannemann , Fernando Racimo

We are interested in modelling Darwinian evolution, resulting from the interplay of phenotypic variation and natural selection through ecological interactions. Our models are rooted in the microscopic, stochastic description of a population…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Régis Ferrière , Sylvie Méléard

George Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission. In this article, I extend Williams' approach to…

Populations and Evolution · Quantitative Biology 2012-01-17 Steven A. Frank

Evolution occurs in populations of reproducing individuals. It is well known that population structure can affect evolutionary dynamics. Traditionally, natural selection is studied between mutants that differ in reproductive rate, but are…

Populations and Evolution · Quantitative Biology 2021-11-23 Josef Tkadlec , Kamran Kaveh , Krishnendu Chatterjee , Martin A. Nowak

In the absence of selection, the structure of allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical patterns of molecular variation. Along with coalescent…

Populations and Evolution · Quantitative Biology 2011-05-30 Michael M. Desai , Lauren E. Nicolaisen , Aleksandra M. Walczak , Joshua B. Plotkin

George Price introduced his famous equation to study selective and environmental effects in discrete populations. We extend Price's framework to the measurable and quantum cases, decomposing all evolutionary processes into selective and…

Probability · Mathematics 2022-12-06 Tom LaGatta

Measures of biodiversity change such as the Living Planet Index describe proportional change in the abundance of a typical species, which can be thought of as change in the size of a community. Here, I discuss the orthogonal concept of…

Populations and Evolution · Quantitative Biology 2014-09-25 Matthew Spencer

This survey focuses on the most important aspects of the mathematical theory of population genetic models of selection and migration between discrete niches. Such models are most appropriate if the dispersal distance is short compared to…

Populations and Evolution · Quantitative Biology 2019-12-13 Reinhard Bürger

A simulation model of a population having internal (genetic) structure is presented. The population is subject to selection pressure coming from the environment which is the same in the whole system but changes in time. Reproduction has a…

Adaptation and Self-Organizing Systems · Physics 2012-08-31 Andrzej Pekalski , Marcel Ausloos

This work aims at providing some (further) perspective into the analysis of two well-known datasets in terms of the methods of linear regression. The first set has been taken from Hubble's 1929 investigation of the relation between the…

History and Philosophy of Physics · Physics 2023-10-03 Evangelos Matsinos

The Ewens sampling formula was firstly introduced in the context of population genetics by Warren John Ewens in 1972, and has appeared in a lot of other scientific fields. There are abundant approximation results associated with the Ewens…

Probability · Mathematics 2022-03-29 Koji Tsukuda

In classical evolutionary theory, genetic variation provides the source of heritable phenotypic variation on which natural selection acts. Against this classical view, several theories have emphasized that developmental variability and…

Populations and Evolution · Quantitative Biology 2011-11-08 Steven A. Frank

We analyse numerically the effects of small population size in the initial transient regime of a simple example population dynamics. These effects play an important role for the numerical determination of large deviation functions of…

Statistical Mechanics · Physics 2017-09-28 Esteban Guevara Hidalgo , Vivien Lecomte

From 1837, when he returned to England aboard the $\textit{HMS Beagle}$, to 1860, just after publication of $\textit{The Origin of Species}$, Charles Darwin kept detailed notes of each book he read or wanted to read. His notes and…

Computation and Language · Computer Science 2018-02-28 Jaimie Murdock , Colin Allen , Simon DeDeo

We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selection, recombination and point mutations. The simplicity of the…

Biological Physics · Physics 2009-11-10 Weiqun Peng , Herbert Levine , Terence Hwa , David A. Kessler

Estimating the number of unseen species is an important problem in many scientific endeavors. Its most popular formulation, introduced by Fisher, uses $n$ samples to predict the number $U$ of hitherto unseen species that would be observed…

Statistics Theory · Mathematics 2016-03-04 Alon Orlitsky , Ananda Theertha Suresh , Yihong Wu

Large populations may contain numerous simultaneously segregating polymorphisms subject to natural selection. Since selection acts on individuals whose fitness depends on many loci, different loci affect each other's dynamics. This leads to…

Populations and Evolution · Quantitative Biology 2011-08-09 Richard A. Neher , Boris I. Shraiman

Since genetic algorithm was proposed by John Holland (Holland J. H., 1975) in the early 1970s, the study of evolutionary algorithm has emerged as a popular research field (Civicioglu & Besdok, 2013). Researchers from various scientific and…

Neural and Evolutionary Computing · Computer Science 2015-08-04 Ka-Chun Wong

In a (two-type) Wright-Fisher diffusion with directional selection and two-way mutation, let $x$ denote today's frequency of the beneficial type, and given $x$, let $h(x)$ be the probability that, among all individuals of today's…

Populations and Evolution · Quantitative Biology 2015-07-10 Ute Lenz , Sandra Kluth , Ellen Baake , Anton Wakolbinger

Understanding the time evolution of fragmented animal populations and their habitats, connected by migration, is a problem of both theoretical and practical interest. This paper presents a method for calculating the time evolution of the…

Populations and Evolution · Quantitative Biology 2008-12-04 Anders Eriksson
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