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Statistical learning algorithms provide a generally-applicable framework to sidestep time-consuming experiments, or accurate physics-based modeling, but they introduce a further source of error on top of the intrinsic limitations of the…

Chemical Physics · Physics 2024-05-17 Matthias Kellner , Michele Ceriotti

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

Machine Learning · Statistics 2022-03-08 Swapneel Mehta , Noah Kasmanoff

A physics-informed neural network (PINN) embedded with the susceptible-infected-removed (SIR) model is devised to understand the temporal evolution dynamics of infectious diseases. Firstly, the effectiveness of this approach is demonstrated…

Quantitative Methods · Quantitative Biology 2025-04-08 Shuai Han , Lukas Stelz , Horst Stoecker , Lingxiao Wang , Kai Zhou

We consider the effect of multiple stochastic parameters on the time-average quantities of chaotic systems. We employ the recently proposed \cite{Kantarakias_Papadakis_2023} sensitivity-enhanced generalized polynomial chaos expansion,…

Chaotic Dynamics · Physics 2023-11-02 George Papadakis , Kyriakos D. Kantarakias

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao

We present a new mathematical model to explicitly capture the effects that the three restriction measures: the lockdown date and duration, social distancing and masks, and, schools and border closing, have in controlling the spread of…

Populations and Evolution · Quantitative Biology 2020-08-25 Liam Dowling Jones , Malik Magdon-Ismail , Laura Mersini-Houghton , Steven Meshnick

This paper proposes a data-driven set-based estimation algorithm for a class of nonlinear systems with polynomial nonlinearities. Using the system's input-output data, the proposed method computes a set that guarantees the inclusion of the…

Systems and Control · Electrical Eng. & Systems 2022-04-01 Amr Alanwar , Muhammad Umar B. Niazi , Karl H. Johansson

This paper investigates the identifiability of a spatial mathematical model of the spread of fast-moving epidemics based on the law of acting masses and diffusion processes. The research algorithm is based on global methods of Sobol…

Optimization and Control · Mathematics 2024-12-30 Olga Krivorotko , Tatiana Zvonareva , Andrei Neverov

While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical…

Populations and Evolution · Quantitative Biology 2020-06-08 Tommaso Alberti , Davide Faranda

The effect of public health interventions on an epidemic are often estimated by adding the intervention to epidemic models. During the Covid-19 epidemic, numerous papers used such methods for making scenario predictions. The majority of…

Methodology · Statistics 2024-10-16 Heejong Bong , Valérie Ventura , Larry Wasserman

We present three data driven model-types for COVID-19 with a minimal number of parameters to provide insights into the spread of the disease that may be used for developing policy responses. The first is exponential growth, widely studied…

Populations and Evolution · Quantitative Biology 2022-05-25 Andrea L. Bertozzi , Elisa Franco , George Mohler , Martin B. Short , Daniel Sledge

The Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model is one of the standard models of disease spreading. Here we analyse an extended SEIR model that accounts for asymptomatic carriers, believed to play an important role…

Populations and Evolution · Quantitative Biology 2021-01-26 Arghya Das , Abhishek Dhar , Srashti Goyal , Anupam Kundu , Saurav Pandey

Integrated Assessment Models (IAMs) are pivotal tools that synthesize knowledge from climate science, economics, and policy to evaluate the interactions between human activities and the climate system. They serve as essential instruments…

General Economics · Economics 2025-11-04 Yongyang Cai

The COVID-19 pandemic has highlighted the importance of in-silico epidemiological modelling in predicting the dynamics of infectious diseases to inform health policy and decision makers about suitable prevention and containment strategies.…

Based on the classical SIR model, we derive a simple modification for the dynamics of epidemics with a known incubation period of infection. The model is described by a system of integro-differential equations. Parameters of our model…

Populations and Evolution · Quantitative Biology 2021-09-01 David B. Saakian

Due to lack of scientific understanding, some mechanisms may be missing in mathematical modeling of complex phenomena in science and engineering. These mathematical models thus contain some uncertainties such as uncertain parameters. One…

Probability · Mathematics 2012-04-05 Jinqiao Duan , Ting Gao , Guowei He

Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns.…

Numerical Analysis · Mathematics 2025-02-19 Caterina Millevoi , Damiano Pasetto , Massimiliano Ferronato

To model the evolution of diseases with extended latency periods and the presence of asymptomatic patients like COVID-19, we define a simple discrete time stochastic SIR-type epidemic model. We include both latent periods as well as the…

Populations and Evolution · Quantitative Biology 2020-05-14 Xavier Bardina , Marco Ferrante , Carles Rovira

The COVID-19 pandemic has posed significant challenges in modeling its complex epidemic transmissions, infection and contagion, which are very different from known epidemics. The challenges in quantifying COVID-19 complexities include…

Machine Learning · Statistics 2022-04-06 Qing Liu , Longbing Cao

In this paper we introduce a novel method to conduct inference with models defined through a continuous-time Markov process, and we apply these results to a classical stochastic SIR model as a case study. Using the inverse-size expansion of…

Applications · Statistics 2011-11-10 Marcos A. Capistrán , J. Andrés Christen , Jorge X. Velasco-Hernández