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The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemination of contradictory model predictions has highlighted…

Populations and Evolution · Quantitative Biology 2020-06-26 Gemma Massonis , Julio R. Banga , Alejandro F. Villaverde

Quantifying uncertainty is important for actionable predictions in real-world applications. A crucial part of predictive uncertainty quantification is the estimation of epistemic uncertainty, which is defined as an integral of the product…

Machine Learning · Computer Science 2023-10-25 Kajetan Schweighofer , Lukas Aichberger , Mykyta Ielanskyi , Günter Klambauer , Sepp Hochreiter

The global pandemic due to the outbreak of COVID-19 ravages the whole world for more than two years in which all the countries are suffering a lot since December 2019. In order to control this ongoing waves of epidemiological infections,…

Populations and Evolution · Quantitative Biology 2022-02-11 Kalpita Ghosh , Asim Kumar Ghosh

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

Graph convolutional neural networks (GCNs) have shown tremendous promise in addressing data-intensive challenges in recent years. In particular, some attempts have been made to improve predictions of Susceptible-Infected-Recovered (SIR)…

Machine Learning · Statistics 2025-01-07 Petr Kisselev , Padmanabhan Seshaiyer

Large-scale testing is considered key to assess the state of the current COVID-19 pandemic. Yet, the link between the reported case numbers and the true state of the pandemic remains elusive. We develop mathematical models based on…

Applications · Statistics 2021-02-04 Michel Besserve , Simon Buchholz , Bernhard Schölkopf

We discuss several issues of statistical design, data collection, analysis, communication, and decision making that have arisen in recent and ongoing coronavirus studies, focusing on tools for assessment and propagation of uncertainty. This…

Applications · Statistics 2020-06-17 Jon Zelner , Julien Riou , Ruth Etzioni , Andrew Gelman

Data-driven forecasts of air quality have recently achieved more accurate short-term predictions. Despite their success, most of the current data-driven solutions lack proper quantifications of model uncertainty that communicate how much to…

Machine Learning · Computer Science 2021-12-07 Abdulmajid Murad , Frank Alexander Kraemer , Kerstin Bach , Gavin Taylor

Mathematical models are widely recognized as an important tool for analyzing and understanding the dynamics of infectious disease outbreaks, predict their future trends, and evaluate public health intervention measures for disease control…

Signal Processing · Electrical Eng. & Systems 2021-06-16 Yukun Tan , Durward Cator , Martial Ndeffo-Mbah , Ulisses Braga-Neto

During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage…

Machine Learning · Computer Science 2021-01-05 Cornelius Fritz , Emilio Dorigatti , David Rügamer

We model further development of the COVID-19 epidemic in the UK given the current data and assuming different scenarios of handling the epidemic. In this research, we further extend the stochastic model suggested in \cite{us} and…

Populations and Evolution · Quantitative Biology 2020-04-10 Anatoly Zhigljavsky , Roger Whitaker , Ivan Fesenko , Kobi Kremnizer , Jack Noonan

Uncertainty quantification is a primary challenge for reliable modeling and simulation of complex stochastic dynamics. Such problems are typically plagued with incomplete information that may enter as uncertainty in the model parameters, or…

Probability · Mathematics 2015-07-15 Paul Dupuis , Markos A. Katsoulakis , Yannis Pantazis , Petr Plechac

Uncertainty quantification is a critical yet unsolved challenge for deep learning, especially for the time series imputation with irregularly sampled measurements. To tackle this problem, we propose a novel framework based on the principles…

Machine Learning · Computer Science 2023-06-05 Shweta Dahale , Sai Munikoti , Balasubramaniam Natarajan

Epidemiological models are best suitable to model an epidemic if the spread pattern is stationary. To deal with non-stationary patterns and multiple waves of an epidemic, we develop a hybrid model encompassing epidemic modeling, particle…

Machine Learning · Computer Science 2024-02-01 Naresh Kumar , Seba Susan

Covid-19 is one of the most dreaded pandemics/epidemics in the world threatening the human population. The dynamics of this pandemic is quite complicated and prediction of pandemic states often fails. In this work, we study and correlate…

Populations and Evolution · Quantitative Biology 2021-10-06 Jyoti Bhadana , R. K. Brojen Singh

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

Computation · Statistics 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

Quantifying uncertainty in a model's predictions is important as it enables the safety of an AI system to be increased by acting on the model's output in an informed manner. This is crucial for applications where the cost of an error is…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Aria Khoshsirat

Parameter estimation and inference from complex survey samples typically focuses on global model parameters whose estimators have asymptotic properties, such as from fixed effects regression models. The central challenge is to both mitigate…

Methodology · Statistics 2026-05-13 Matthew R. Williams , F. Hunter McGuire , Terrance D. Savitsky

The SIR-compartment model is among the simplest models that describe the spread of a disease through a population. The model makes the unrealistic assumption that the population through which the disease is spreading is well-mixed. Although…

Populations and Evolution · Quantitative Biology 2022-11-16 Ryan Wilkinson , Marcus Roper

Uncertainty-quantification methods are applied to estimate the confidence of deep-neural-networks classifiers over their predictions. However, most widely used methods are known to be overconfident. We address this problem by developing an…

Machine Learning · Computer Science 2023-05-19 Luigi Sbailò , Luca M. Ghiringhelli