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Health impact simulation models are used to predict how a proposed intervention or scenario will affect public health outcomes, based on available data and knowledge of the process. The outputs of these models are uncertain due to…

The evolution of the COVID-19 epidemic has been accompanied by accumulating evidence on the underlying epidemiological parameters. Hence there is potential for models providing mid-term forecasts of the epidemic trajectory using such…

Applications · Statistics 2020-11-10 Peter Congdon

Machine learning (ML) surrogate models are increasingly used in engineering analysis and design to replace computationally expensive simulation models, significantly reducing computational cost and accelerating decision-making processes.…

Machine Learning · Statistics 2025-07-22 Xiaoping Du

Since December 2019, A novel coronavirus (2019-nCoV) has been breaking out in China, which can cause respiratory diseases and severe pneumonia. Mathematical and empirical models relying on the epidemic situation scale for forecasting…

Populations and Evolution · Quantitative Biology 2021-01-05 Jingyuan Wang , Xin Lin , Yuxi Liu , Qilegeri , Kai Feng , Hui Lin

The classic SIR model of epidemic dynamics is solved completely by quadratures, including a time integral transform expanded in a series of incomplete gamma functions. The model is also generalized to arbitrary time-dependent infection…

Populations and Evolution · Quantitative Biology 2020-10-07 E. Sadurní , G. Luna-Acosta

Effective and reliable screening of patients via Computer-Aided Diagnosis can play a crucial part in the battle against COVID-19. Most of the existing works focus on developing sophisticated methods yielding high detection performance, yet…

Computer Vision and Pattern Recognition · Computer Science 2021-05-11 Krishanu Sarker , Sharbani Pandit , Anupam Sarker , Saeid Belkasim , Shihao Ji

For safe and reliable deployment in the real world, autonomous agents must elicit appropriate levels of trust from human users. One method to build trust is to have agents assess and communicate their own competencies for performing given…

Robotics · Computer Science 2022-06-22 Aastha Acharya , Rebecca Russell , Nisar R. Ahmed

Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but…

Populations and Evolution · Quantitative Biology 2020-06-02 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt

When the novel coronavirus disease SARS-CoV2 (COVID-19) was officially declared a pandemic by the WHO in March 2020, the scientific community had already braced up in the effort of making sense of the fast-growing wealth of data gathered by…

Populations and Evolution · Quantitative Biology 2020-05-25 Timoteo Carletti , Duccio Fanelli , Francesco Piazza

Growing uncertainty from renewable energy integration and distributed energy resources motivate the need for advanced tools to quantify the effect of uncertainty and assess the risks it poses to secure system operation. Polynomial chaos…

Optimization and Control · Mathematics 2019-10-16 David Métivier , Marc Vuffray , Sidhant Misra

In context-specific applications such as robotics, telecommunications, and healthcare, artificial intelligence systems often face the challenge of limited training data. This scarcity introduces epistemic uncertainty, i.e., reducible…

Information Theory · Computer Science 2026-03-17 Osvaldo Simeone , Yaniv Romano

In personalized medicine, the ability to predict and optimize treatment outcomes across various time frames is essential. Additionally, the ability to select cost-effective treatments within specific budget constraints is critical. Despite…

Machine Learning · Computer Science 2024-10-14 Thomas Schwarz , Cecilia Casolo , Niki Kilbertus

Understanding the spread of SARS-CoV-2 has been one of the most pressing problems of the recent past. Network models present a potent approach to studying such spreading phenomena because of their ability to represent complex social…

Social and Information Networks · Computer Science 2023-11-01 Christine Hedde-von Westernhagen , Javier Garcia-Bernardo , Ayoub Bagheri

The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…

Applications · Statistics 2021-04-15 Claire Donnat , Susan Holmes

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation…

Applications · Statistics 2020-10-30 Philip Nadler , Shuo Wang , Rossella Arcucci , Xian Yang , Yike Guo

Because of the rapid spread of COVID-19 to almost every part of the globe, huge volumes of data and case studies have been made available, providing researchers with a unique opportunity to find trends and make discoveries like never…

Machine Learning · Computer Science 2021-10-20 Sarwan Ali , Yijing Zhou , Murray Patterson

The importance of uncertainty quantification is increasingly recognized in the diverse field of machine learning. Accurately assessing model prediction uncertainty can help provide deeper understanding and confidence for researchers and…

Machine Learning · Computer Science 2024-12-03 Tianyi Chen , Yingzhou Lu , Nan Hao , Yuanyuan Zhang , Capucine Van Rechem , Jintai Chen , Tianfan Fu

The COVID-19 pandemic has highlighted the need for quantitative modeling and analysis to understand real-world disease dynamics. In particular, post hoc analyses using compartmental models offer valuable insights into the effectiveness of…

Machine Learning · Computer Science 2025-10-09 Phillip Rothenbeck , Sai Karthikeya Vemuri , Niklas Penzel , Joachim Denzler

As the COVID19 spreads across the world, prevention measures are becoming the essential weapons to combat the pandemic in the period of crisis. The lockdown measure is the most controversial one as it imposes an overwhelming impact on our…

Physics and Society · Physics 2021-02-12 Yuting Fu , Haitao Xiang , Hanqing Jin , Ning Wang

Estimating, understanding, and communicating uncertainty is fundamental to statistical epidemiology, where model-based estimates regularly inform real-world decisions. However, sources of uncertainty are rarely formalised, and existing…

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