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This study investigated the performance, explainability, and robustness of deployed artificial intelligence (AI) models in predicting mortality during the COVID-19 pandemic and beyond. The first study of its kind, we found that Bayesian…

Machine Learning · Computer Science 2023-11-30 Jacob R. Epifano , Stephen Glass , Ravi P. Ramachandran , Sharad Patel , Aaron J. Masino , Ghulam Rasool

Compartmental models are an important quantitative tool in epidemiology, enabling us to forecast the course of a communicable disease. However, the model parameters, such as the infectivity rate of the disease, are riddled with…

Populations and Evolution · Quantitative Biology 2023-01-12 Konstantinos Mamis , Mohammad Farazmand

Intent of this research is to explore how mathematical models, specifically Susceptible-Infected-Removed (SIR) model, can be utilized to forecast peak outbreak timeline of COVID-19 epidemic amongst a population of interest starting from the…

Populations and Evolution · Quantitative Biology 2020-09-14 Amit Tewari

The present article studies the extension of two deterministic models for describing the novel coronavirus pandemic crisis, the SIR model and the SEIR model. The models were studied and compared to real data in order to support the validity…

Physics and Society · Physics 2020-06-05 P. H. P. Cintra , M. F. Citeli , F. N. Fontinele

Pandemic(epidemic) modeling, aiming at disease spreading analysis, has always been a popular research topic especially following the outbreak of COVID-19 in 2019. Some representative models including SIR-based deep learning prediction…

Machine Learning · Computer Science 2022-12-07 Danfeng Guo , Zijie Huang , Junheng Hao , Yizhou Sun , Wei Wang , Demetri Terzopoulos

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

Uncertainty quantification (UQ) techniques are frequently used to ascertain output variability in systems with parametric uncertainty. Traditional algorithms for UQ are either system-agnostic and slow (such as Monte Carlo) or fast with…

Computation · Statistics 2015-03-19 Tuhin Sahai , Jose Miguel Pasini

We propose a stochastic SIR model, specified as a system of stochastic differential equations, to analyse the data of the Italian COVID-19 epidemic, taking also into account the under-detection of infected and recovered individuals in the…

Populations and Evolution · Quantitative Biology 2021-02-22 Sara Pasquali , Antonio Pievatolo , Antonella Bodini , Fabrizio Ruggeri

Verification solutions for uncertainty quantification are presented for time dependent transport problems where $c$, the scattering ratio, is uncertain. The method of polynomial chaos expansions is employed for quick and accurate…

Computational Engineering, Finance, and Science · Computer Science 2023-12-19 William Bennett , Ryan G. McClarren

We construct an SIR-type model for COVID-19, incorporating as a parameter the susceptible individuals' cautiousness level. We determine the model's basic reproduction number, study the stability of the equilibria analytically, and perform a…

Dynamical Systems · Mathematics 2022-04-06 Benny Yong , Livia Owen , Jonathan Hoseana

Uncertainty quantification for complex deep learning models is increasingly important as these techniques see growing use in high-stakes, real-world settings. Currently, the quality of a model's uncertainty is evaluated using…

Machine Learning · Computer Science 2021-12-15 Benjamin Kompa , Jasper Snoek , Andrew Beam

We study the impact of model parameter uncertainty on optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic model and consider testing for isolation as…

Systems and Control · Electrical Eng. & Systems 2022-09-07 Baike She , Shreyas Sundaram , Philip E. Paré

Stochastic simulation has been widely used to analyze the performance of complex stochastic systems and facilitate decision making in those systems. Stochastic simulation is driven by the input model, which is a collection of probability…

Risk Management · Quantitative Finance 2020-02-14 Tianyi Liu , Enlu Zhou

Resilience characterizes a system's ability to retain its original function when perturbations happen. In the past years our attention mainly focused on small-scale resilience, yet our understanding of resilience in large-scale network…

Adaptation and Self-Organizing Systems · Physics 2020-10-13 Mengbang Zou , Luca Zanotti Fragonara , Weisi Guo

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

In scientific applications, there often are several competing models that could be fit to the observed data, so quantification of the model uncertainty is of fundamental importance. In this paper, we develop an inferential model (IM)…

Statistics Theory · Mathematics 2016-06-07 Ryan Martin , Huiping Xu , Zuoyi Zhang , Chuanhai Liu

Predicting Pandemic evolution involves complex modeling challenges, often requiring detailed discrete mathematics executed on large volumes of epidemiological data. Differential equations have the advantage of offering smooth, well-behaved…

Biological Physics · Physics 2023-02-28 Clara Bender , Abhimanyu Ghosh , Hamed Vakili , Preetam Ghosh , Avik W. Ghosh

Computational models for the simulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic evolution would be extremely useful to support authorities in designing healthcare policies and lockdown measures to…

Populations and Evolution · Quantitative Biology 2020-04-20 Marco Paggi

Global pandemics, such as the recent COVID-19 crisis, highlight the need for stochastic epidemic models that can capture the randomness inherent in the spread of disease. Such models must be accompanied by methods for estimating parameters…

Quantitative Methods · Quantitative Biology 2026-04-13 Vincent Wieland , Nils Wassmuth , Lorenzo Contento , Martin Kühn , Jan Hasenauer

This paper extends the canonical model of epidemiology, the SIRD model, to allow for time-varying parameters for real-time measurement and prediction of the trajectory of the Covid-19 pandemic. Time variation in model parameters is captured…

Econometrics · Economics 2023-02-01 Cem Cakmakli , Yasin Simsek