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In this paper we describe the dynamics of a vector-borne relapsing disease, such as tick-borne relapsing fever, using the methods of compartmental models. After some motivation, model description, and a brief overview of the theory of…

Dynamical Systems · Mathematics 2016-08-24 Cody Palmer , Erin Landguth , Emily Stone , Tammi Johnson

Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that…

Quantitative Methods · Quantitative Biology 2022-12-01 Nir Gavish , Guy Katriel

We consider the problem of estimating the reproduction number $R_t$ of an epidemic for populations where the probability of detection of cases depends on a known covariate. We argue that in such cases the normal empirical estimator can fail…

Applications · Statistics 2020-12-04 Guido Sanguinetti

In this paper, we derive and analyse a model for the control of arboviral diseases which takes into account an imperfect vaccine combined with some other mechanisms of control already studied in the literature. We begin by analyse the basic…

Dynamical Systems · Mathematics 2016-01-12 Hamadjam Abboubakar , Jean-Claude Kamgang , Daniel Tieudjo

Optimization is at the core of control theory and appears in several areas of this field, such as optimal control, distributed control, system identification, robust control, state estimation, model predictive control and dynamic…

Optimization and Control · Mathematics 2019-03-14 Richard Y. Zhang , Cédric Josz , Somayeh Sojoudi

A great issue of discussion of an infectious disease is its basic reproduction number R0, which provides an estimation of the contagiousness of the disease. When R0 > 1, the disease spread will potentially lead to an outbreak, such that of…

Populations and Evolution · Quantitative Biology 2021-01-18 Dimitrios G. Patsatzis

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

Dynamical Systems · Mathematics 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…

Populations and Evolution · Quantitative Biology 2026-04-14 Michael J. Plank , Matt Ryan , Lloyd Chapman , Roslyn I. Hickson , Thomas House , Emma McBryde , James M. McCaw

The basic reproduction ratio is a crucial threshold parameter in infectious disease models. In nonlocal dispersal systems, its variational characterization is challenging due to the possible absence of a principal eigenvalue caused by…

Analysis of PDEs · Mathematics 2026-05-27 Xiandong Lin , Jiazhuo Cheng , Qiru Wang

Many studies have proposed a relationship between COVID-19 transmissibility and ambient pollution levels. However, a major limitation in establishing such associations is to adequately account for complex disease dynamics, influenced by…

Populations and Evolution · Quantitative Biology 2021-09-07 Ognjen Milicevic , Igor Salom , Andjela Rodic , Sofija Markovic , Marko Tumbas , Dusan Zigic , Magdalena Djordjevic , Marko Djordjevic

We show that the basic reproduction number of an SIS patch model with standard incidence is either strictly decreasing and strictly convex with respect to the diffusion coefficient of infected subpopulation if the patch reproduction numbers…

Populations and Evolution · Quantitative Biology 2020-01-03 Daozhou Gao , Chao-Ping Dong

Recent research indicates that many convex optimization problems with random constraints exhibit a phase transition as the number of constraints increases. For example, this phenomenon emerges in the $\ell_1$ minimization method for…

Information Theory · Computer Science 2014-04-29 Dennis Amelunxen , Martin Lotz , Michael B. McCoy , Joel A. Tropp

There are few adapted SIR models in the literature that combine vaccination and logistic growth. In this article, we study bifurcations of a SIR model where the class of Susceptible individuals grows logistically and has been subject to…

Dynamical Systems · Mathematics 2023-04-26 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

This present results lay the foundations for the study of the optimal allocation of vaccine in the simple epidemiological SIS model where one consider a very general heterogeneous population. In the present setting each individual has a…

Populations and Evolution · Quantitative Biology 2025-04-02 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Predictive contagion models are ubiquitous in epidemiology, social sciences, engineering, and management. This paper formulates a prescriptive contagion analytics model where a decision-maker allocates shared resources across multiple…

Optimization and Control · Mathematics 2023-10-24 Alexandre Jacquillat , Michael Lingzhi Li , Martin Ramé , Kai Wang

A wide range of infectious diseases are both vertically and horizontally transmitted. Such diseases are spatially transmitted via multiple species in heterogeneous environments, typically described by complex meta-population models. The…

Populations and Evolution · Quantitative Biology 2013-03-05 Ling Xue , Caterina Scoglio

We define data analyses to monitor a change in R, the average number of secondary cases caused by a typical infected individual. The input dataset consists of incident cases partitioned into outbreaks, each initiated from a single index…

Populations and Evolution · Quantitative Biology 2016-04-27 Pavel Polyakov , Romulus Breban

Prior knowledge on properties of a target model often come as discrete or combinatorial descriptions. This work provides a unified computational framework for defining norms that promote such structures. More specifically, we develop…

Machine Learning · Statistics 2019-04-11 Amin Jalali , Adel Javanmard , Maryam Fazel

Recently, there has been an increasing interest in designing distributed convex optimization algorithms under the setting where the data matrix is partitioned on features. Algorithms under this setting sometimes have many advantages over…

Machine Learning · Computer Science 2016-12-05 Zihao Chen , Luo Luo , Zhihua Zhang
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