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This study presents a deterministic model to investigate rabies transmission dynamics, incorporating environmental effects and control strategies using optimal control theory. Qualitative and quantitative analyses reveal that the…

Optimization and Control · Mathematics 2025-09-05 Mfano Charles , Sayoki G. Mfinanga , G. A. Lyakurwa , Delfim F. M. Torres , Verdiana G. Masanja

The success of an infectious disease to invade a population is strongly controlled by the population's specific connectivity structure. Here a network model is presented as an aid in understanding the role of social behavior and…

Cellular Automata and Lattice Gases · Physics 2007-07-10 Anna Litvak-Hinenzon , Lewi Stone

This paper introduces Roundabout Constrained Convex Generators (RCGs), a set representation framework for modeling multiply connected regions in control and verification applications. The RCG representation extends the constrained convex…

Optimization and Control · Mathematics 2025-11-11 Peng Xie , Sabin Diaconescu , Florin Stoican , Amr Alanwar

We consider a single outbreak susceptible-infected-recovered (SIR) model and corresponding estimation procedures for the effective reproductive number $\mathcal{R}(t)$. We discuss the estimation of the underlying SIR parameters with a…

Populations and Evolution · Quantitative Biology 2020-04-16 Ariel Cintrón-Arias , Carlos Castillo-Chávez , Luís M. A. Bettencourt , Alun L. Lloyd , H. T. Banks

An impulsive model of augmentative biological control consisting of a general continuous predator-prey model in ordinary differential equations augmented by a discrete part describing periodic introductions of predators is considered. It is…

Optimization and Control · Mathematics 2009-09-29 Ludovic Mailleret , Frédéric Grognard

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

Populations and Evolution · Quantitative Biology 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

Methodology · Statistics 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

Probability · Mathematics 2018-02-15 Carolina Fransson , Pieter Trapman

When fitting a multi-parameter model to a data set, computer algorithms may suggest that a range of parameters provide equally reasonable fits, making the parameter estimation difficult. Here, we prove this fact for an SIR model. We say a…

Populations and Evolution · Quantitative Biology 2024-04-08 B Shayak , Sana Jahedi , James A Yorke

The term radicalization refers to the process of developing extremist religious political or social beliefs and ideologies. Radicalization becomes a threat to national security when it leads to violence. Prevention and de-radicalization…

Physics and Society · Physics 2020-06-12 Manuele Santoprete

Plant diseases often cause serious yield losses in agriculture. A pathogen's reproductive fitness can be quantified by the basic reproductive number, R0. Since pathogen transmission between host plants depends on the spatial separation…

Populations and Evolution · Quantitative Biology 2014-10-03 Alexey Mikaberidze , Christopher C. Mundt , Sebastian Bonhoeffer

Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

Populations and Evolution · Quantitative Biology 2026-03-12 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

Chance-constrained programming (CCP) is one of the most difficult classes of optimization problems that has attracted the attention of researchers since the 1950s. In this survey, we focus on cases when only a limited information on the…

Optimization and Control · Mathematics 2022-02-15 Simge Küçükyavuz , Ruiwei Jiang

This paper is about numerical control of HIV propagation. The contribution of the paper is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the…

Systems and Control · Computer Science 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan O. Romero-Severson , Oana Silvia Serea

Principal component analysis (PCA) is known to be sensitive to outliers, so that various robust PCA variants were proposed in the literature. A recent model, called REAPER, aims to find the principal components by solving a convex…

Numerical Analysis · Mathematics 2021-03-19 Robert Beinert , Gabriele Steidl

This paper proposes distributed algorithms to solve robust convex optimization (RCO) when the constraints are affected by nonlinear uncertainty. We adopt a scenario approach by randomly sampling the uncertainty set. To facilitate the…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-01-16 Keyou You , Roberto Tempo , Pei Xie

Infection can spread easily on networks with heterogeneous degree distribution. Here, we considered targeted immunization on such networks, wherein a fraction of individuals with the highest connectivity are immunized. To quantify the…

Physics and Society · Physics 2021-11-05 Satoru Morita

We study a class of structured optimal control problems in which the main diagonal of the dynamic matrix is a linear function of the design variable. While such problems are in general challenging and nonconvex, for positive systems we…

Optimization and Control · Mathematics 2019-07-09 Neil K. Dhingra , Marcello Colombino , Mihailo R. Jovanović

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

Ordinary differential equation (ODE) models used in mathematical epidemiology assume explicitly or implicitly large populations. For the study of infections in a hospital this is an extremely restrictive assumption as typically a hospital…

Populations and Evolution · Quantitative Biology 2023-08-21 Fabio A. C. C. Chalub , Antonio Gómez-Corral , Martín López-García , Fátima Palacios-Rodríguez
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