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The galaxy quenching process, in which a galaxy stops forming stars is a crucial stage in galaxy life. Two mechanisms for quenching are possible: halo mass quenching of central galaxies and environmental quenching of satellite galaxies.…
Evolutionary synthesis models for star clusters of various metallicities including gaseous emission during the lifetime of the ionising stars are used to model star cluster systems comprising two populations: an old metal-poor globular…
Adopting a single-zone framework, with accretion of primordial gas on a free-fall timescale, the chemical evolution of the Galactic bulge is calculated, assuming (i) a corresponding rapid timescale for star formation, and (ii) an initial…
Efficient energy transduction is one driver of evolution; and thus understanding biomolecular energy transduction is crucial to understanding living organisms. As an energy-orientated modelling methodology, bond graphs provide a useful…
Recent developments relevant to the formation of globular cluster systems in galaxies are discussed, including (1) The age distribution of the oldest Milky Way clusters, (2) Subgroups and possible accretion and merger remnants in the…
A core topic of research in prebiotic chemistry is the search for plausible synthetic routes that connect the building blocks of modern life such as sugars, nucleotides, amino acids, and lipids to "molecular food sources" that have likely…
We investigate the nature of Lyman break galaxies (LBGs) using a chemodynamical model for evolution of galaxies. Our models predict an early (the first Gyr) stage of intense star formation in the evolution of massive spheroids which could…
We first discuss recent progress in using the Milky Way globular cluster (GC) system as a `test-bed' for properties derived from integrated spectra and stellar population models. Standard techniques may give rise to spuriously high…
Evolving one-dimensional cellular automata (CAs) with genetic algorithms has provided insight into how improved performance on a task requiring global coordination emerges when only local interactions are possible. Two approaches that can…
Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonmous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of…
The current understanding of galaxy formation is that it proceeds in a 'bottom up' way, with the formation of small clumps of gas and stars that merge hierarchically until giant galaxies are built up. The baryonic gas loses the thermal…
Galactic archaeology is the study of the history of star formation and chemical evolution in the Milky Way, based on present-day stellar populations. Studies of young stars are a key anchor point for Galactic archaeology, since quantities…
How the Milky Way has accumulated its mass over the Hubble time, whether significant amounts of gas and stars were accreted from satellite galaxies, or whether the Milky Way has experienced an initial gas assembly and then evolved…
Globular clusters (GCs) are powerful tracers of galaxy assembly, frequently used to identify accreted substructure and reconstruct hierarchical merger histories. With advances in GC formation models and cosmological simulations, we can now…
We investigate a quantitative network of gene expression dynamics describing the competence development in Bacillus subtilis. First, we introduce an Onsager-Machlup approach to quantify the most probable transition pathway for both…
A classic problem in microbiology is that bacteria display two types of growth behavior when cultured on a mixture of two carbon sources: the two sources are sequentially consumed one after another (diauxie) or they are simultaneously…
Globular clusters (GCs) are sensitive tracers of galaxy assembly histories but interpreting the information they encode is challenging because mergers are thought to promote both the formation and disruption of GCs. We use simulations with…
In this review I will discuss the comparison between model results and observational data for the Milky Way, the predictive power of such models as well as their limits. Such a comparison, known as Galactic archaeology, allows us to impose…
Open clusters and associations are groups of young stars, respectively bound and unbound, that share the same origin and disperse over time into the galactic field. As such, their formation and evolution are the key to understand the origin…
Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…