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We investigate the physical properties of the progenitors of today living Milky Way-like galaxies that are visible as Damped Lya Absorption systems and Lya Emitters at higher redshifts (z ~ 2.3,5.7). To this aim we use a statistical…
We explore the transport mechanisms of heat in two- and three-dimensional turbulent convection flows by means of the long-term evolution of Lagrangian coherent sets. They are obtained from the spectral clustering of trajectories of massless…
We present a new set of evolutionary synthesis models of our GALEV code, specifically developed to include the gaseous emission of presently forming star clusters, in combination with an advanced tool to compare large model grids with…
Signaling pathways serve to communicate information about extracellular conditions into the cell, to both the nucleus and cytoplasmic processes to control cell responses. Genetic mutations in signaling network components are frequently…
The two classic theories for the existence of sexual replication are that sex purges deleterious mutations from a population, and that sex allows a population to adapt more rapidly to changing environments. These two theories have often…
The universality of many pathways of core metabolism suggests a strong role for evolutionary selection, but it remains unclear whether existing pathways have been selected from a large or small set of biochemical possibilities. To address…
The Bulge Asymmetries and Dynamical Evolution (BAaDE) survey will provide positions and line-of-sight velocities of ~20,000 evolved, maser bearing stars in the Galactic plane. Although this Galactic region is affected by optical extinction,…
We study a class of growth algorithms for directed graphs that are candidate models for the evolution of genetic regulatory networks. The algorithms involve partial duplication of nodes and their links, together with innovation of new…
Biological networks exhibit intricate architectures deemed to be crucial for their functionality. In particular, gene regulatory networks, which play a key role in information processing in the cell, display non-trivial architectural…
We investigate the dynamical properties of the transcriptional regulation of gene expression in the yeast Saccharomyces Cerevisiae within the framework of a synchronously and deterministically updated Boolean network model. By means of a…
The evolutionary transition to multicellularity transformed life on earth, allowing for the evolution of large, complex organisms. While multicellularity can be strongly advantageous, its earliest stages bring unique physical challenges.…
We use SDSS+\textit{GALEX}+Galaxy Zoo data to study the quenching of star formation in low-redshift galaxies. We show that the green valley between the blue cloud of star-forming galaxies and the red sequence of quiescent galaxies in the…
The present and future of evolutionary algorithms depends on the proper use of modern parallel and distributed computing infrastructures. Although still sequential approaches dominate the landscape, available multi-core, many-core and…
A central and long-standing issue in evolutionary theory is the origin of the biological variation upon which natural selection acts1. Some hypotheses suggest that evolutionary change represents an adaptation to the surrounding environment…
Cellular nutrient consumption is influenced by both the nutrient uptake kinetics of an individual cell and the cells' spatial arrangement. Large cell clusters or colonies have inhibited growth at the cluster's center due to the shielding of…
Disease occurs due to aberrant expression of genes and modulation of the biological pathways along which they lie. Inference of activated gene pathways, using gene expression data during disease progression, is an important problem. In this…
Within the Cold Dark Matter scenario the hierarchical merging paradigm is the natural result to form massive galactic halos by the minor mergers of sub-halos and, by this, inherently their stellar halo. Although this must be also invoked…
Open clusters are the only example of single-age, single initial chemical composition populations in the Galaxy, and they play an important role in the study of the formation and evolution of the Galactic disk. In addition, they have been…
For several decades now, open clusters have been used to study the structure and chemical evolution of the disk of our Galaxy. Due to the fact that their ages and metallicities can be determined with relatively good precision, and since…
The pathogenesis of cancer in human is still poorly understood. With the rapid development of high-throughput sequencing technologies, huge volumes of cancer genomics data have been generated. Deciphering those data poses great…