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Purpose: To present a fully open-source framework for quasi-real-time streaming and cloud-based processing of low-field (LF) MRI data, addressing the growing computational demands of advanced reconstruction and post-processing pipelines in…

Ultrasound imaging is developing an open-source ecosystem, especially for software frameworks. Little exists on the open-hardware side. Hence a focus was put on producing easy-to-use technological (hardware and software) kit to allow anyone…

Medical Physics · Physics 2019-07-16 Luc Jonveaux

High-Content Digital Microscopy enhances user comfort, data storage and analysis throughput, paving the way to new researches and medical diagnostics. A digital microscopy platform aims at capturing an image of a cover slip, at storing…

Computational Engineering, Finance, and Science · Computer Science 2014-04-30 Fabrice Salvaire

Sample-induced image-degradation remains an intricate wave-optical problem in light-sheet microscopy. Here we present biobeam, an open-source software package that enables to simulate operational light-sheet microscopes by combining data…

Biological Physics · Physics 2018-07-04 Martin Weigert , Eugene W. Myers , Moritz Kreysing

Remote observations are often limited by user interfaces, which seem frozen to another computer era: low performances, outdated programming languages, command-line scripting, high version-dependent software. Instead, web-based tools are…

Instrumentation and Methods for Astrophysics · Physics 2025-01-15 Davide Ricci , Lorenzo Cabona , Bernardo Salasnich , Luciano Nicastro , Luca Fini , Andrea Damonte , Silvano Tosi , Takashi Shibata

Microscopy, in particular scanning probe and electron microscopy, has been pivotal in improving our understanding of structure-function relationships at the nanoscale and is by now ubiquitous in most research characterization labs and…

Microscopes are vital pieces of equipment in much of biological research and medical diagnostics. However, access to a microscope can represent a bottleneck in research, especially in lower-income countries. `Smart' computer controlled…

Instrumentation and Detectors · Physics 2022-07-08 Samuel McDermott , Filip Ayazi , Joel Collins , Joe Knapper , Julian Stirling , Richard Bowman , Pietro Cicuta

A holographic microscope captures interference patterns, or holograms, that encode three-dimensional (3D) information about the object being viewed. Computation is essential to extracting that 3D information. By wrapping low-level…

Image and Video Processing · Electrical Eng. & Systems 2018-06-04 Solomon Barkley , Thomas G. Dimiduk , Jerome Fung , David M. Kaz , Vinothan N. Manoharan , Ryan McGorty , Rebecca W. Perry , Anna Wang

Achieving fast, large-scale volumetric imaging with micrometer resolution has been a persistent challenge in the field of biological microscopy. To address this challenge, we report an augmented version of light field microscopy,…

Optics · Physics 2024-10-11 Aymerick Bazin , Amaury Badon

Biological cell imaging has become one of the most crucial research interests due to its wide-ranging applications in biomedical and microbiology studies. However, three-dimensional (3D) imaging of biological cells remains critically…

The fabrication of multilayered heterostructures is essential for advancing microelectronic and biosensing technologies. Conventional top-down manufacturing techniques are often cost-prohibitive and unsuitable for biomedical applications.…

Chemical Physics · Physics 2025-06-13 Anand Dev Ranjan , Suyash Narayan Amzare , Subhrokoli Ghosh , Ayan Banerjee

Web browsers are increasingly used as middleware platforms offering a central access point for service provision. Using backend containerization, RESTful APIs, and distributed computing allows for complex systems to be realized that address…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-03 Rudolph Pienaar , Ata Turk , Jorge Bernal-Rusiel , Nicolas Rannou , Daniel Haehn , P. Ellen Grant , Orran Krieger

Light sheet microscopy promises to revolutionize developmental biology by enabling live in toto imaging of entire embryos with minimal phototoxicity. We present detailed instructions for building a compact and customizable Selective Plane…

The aim of this paper is to give an introductory review of the cryoelectron microscopy as a complex data source for the most of the system biology branches, including the most perspective non-local approaches known as "localomics" and…

Subcellular Processes · Quantitative Biology 2015-01-20 Oleg V. Gradov , Margaret A. Gradova

The digitization of biological specimens has revolutionized the field of morphology, creating large collections of 3D data, and microCT in particular. This revolution was initially supported by the development of open-source software tools,…

Other Quantitative Biology · Quantitative Biology 2026-01-22 A. Murat Maga , Jean-Christophe Fillion-Robin

Endomicroscopy is an emerging imaging modality, that facilitates the acquisition of in vivo, in situ optical biopsies, assisting diagnostic and potentially therapeutic interventions. While there is a diverse and constantly expanding range…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Antonios Perperidis , Kevin Dhaliwal , Stephen McLaughlin , Tom Vercauteren

Microscopes have morphed from purely optical instruments into motorized, robotic machines that form images on digital sensors rather than eyeballs. This continuing trend towards automation and digitization enables many new approaches to…

Other Quantitative Biology · Quantitative Biology 2020-05-04 Raghav Chhetri , Stephan Preibisch , Nico Stuurman

The complexity and scale of Internet attacks call for distributed, cooperative observatories capable of monitoring malicious traffic across diverse networks. Holoscope is a lightweight, cloud-native platform designed to simplify the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-24 Andrea Sordello , Marco Mellia , Idilio Drago , Rodolfo Valentim , Francesco Musumeci , Massimo Tornatore , Federico Cerutti , Martino Trevisan , Alessio Botta , Willen Borges Coelho

Microscopic analysis of micro particles in situ in diverse water environments is necessary for monitoring water quality and localizing contamination sources. Conventional sensors such as optical microscopes and fluorometers often require…

Robotics · Computer Science 2019-11-26 Kevin Mallery , Dario Canelon , Jiarong Hong , Nikolaos Papanikolopoulos

Use of commercial growth chambers for study of biological processes involved in biomass growth and production pose certain limitations on the nature of studies that can be performed in them. Optimization of biomass rearing and production…

Quantitative Methods · Quantitative Biology 2020-04-16 Murali Padmanabha , Stefan Streif