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Large Language Models (LLMs) have demonstrated remarkable performance across various domains, including healthcare. However, their ability to effectively represent structured non-textual data, such as the alphanumeric medical codes used in…

Developing high-performance entity normalization algorithms that can alleviate the term variation problem is of great interest to the biomedical community. Although deep learning-based methods have been successfully applied to biomedical…

Information Retrieval · Computer Science 2019-08-12 Zongcheng Ji , Qiang Wei , Hua Xu

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

The exponential increase in scientific literature and online information necessitates efficient methods for extracting knowledge from textual data. Natural language processing (NLP) plays a crucial role in addressing this challenge,…

Computation and Language · Computer Science 2025-10-22 Zhyar Rzgar K. Rostam , Gábor Kertész

Pre-trained Language Models (PLMs) have shown superior performance on various downstream Natural Language Processing (NLP) tasks. However, conventional pre-training objectives do not explicitly model relational facts in text, which are…

Computation and Language · Computer Science 2021-05-27 Yujia Qin , Yankai Lin , Ryuichi Takanobu , Zhiyuan Liu , Peng Li , Heng Ji , Minlie Huang , Maosong Sun , Jie Zhou

With the rapid advancement of semiconductor technology, Electronic Design Automation (EDA) has become an increasingly knowledge-intensive and document-driven engineering domain. Although large language models (LLMs) have shown strong…

Machine Learning · Computer Science 2026-05-01 Lei Li , Xingwen Yu , Jianguo Ni , Junxuan Zhu , Jieqiong Zhang , Jian Zhao , Zhi Liu

Injecting external domain-specific knowledge (e.g., UMLS) into pretrained language models (LMs) advances their capability to handle specialised in-domain tasks such as biomedical entity linking (BEL). However, such abundant expert knowledge…

Computation and Language · Computer Science 2021-06-01 Fangyu Liu , Ivan Vulić , Anna Korhonen , Nigel Collier

Language models pretrained on text from a wide variety of sources form the foundation of today's NLP. In light of the success of these broad-coverage models, we investigate whether it is still helpful to tailor a pretrained model to the…

Computation and Language · Computer Science 2020-05-07 Suchin Gururangan , Ana Marasović , Swabha Swayamdipta , Kyle Lo , Iz Beltagy , Doug Downey , Noah A. Smith

Most natural language tasks in the radiology domain use language models pre-trained on biomedical corpus. There are few pretrained language models trained specifically for radiology, and fewer still that have been trained in a low data…

Computation and Language · Computer Science 2023-06-06 Rikhiya Ghosh , Sanjeev Kumar Karn , Manuela Daniela Danu , Larisa Micu , Ramya Vunikili , Oladimeji Farri

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

Pre-trained language models induce dense entity representations that offer strong performance on entity-centric NLP tasks, but such representations are not immediately interpretable. This can be a barrier to model uptake in important…

Computation and Language · Computer Science 2021-06-18 Diego Garcia-Olano , Yasumasa Onoe , Ioana Baldini , Joydeep Ghosh , Byron C. Wallace , Kush R. Varshney

In this study, we investigate the potential of Large Language Models to complement biomedical knowledge graphs in the training of semantic models for the biomedical and clinical domains. Drawing on the wealth of the UMLS knowledge graph and…

Computation and Language · Computer Science 2023-11-28 François Remy , Kris Demuynck , Thomas Demeester

Pre-trained language models (PLMs) have achieved remarkable success on various natural language understanding tasks. Simple fine-tuning of PLMs, on the other hand, might be suboptimal for domain-specific tasks because they cannot possibly…

Computation and Language · Computer Science 2022-08-05 Minki Kang , Jinheon Baek , Sung Ju Hwang

There has been an influx of biomedical domain-specific language models, showing language models pre-trained on biomedical text perform better on biomedical domain benchmarks than those trained on general domain text corpora such as…

Computation and Language · Computer Science 2020-10-15 Hoo-Chang Shin , Yang Zhang , Evelina Bakhturina , Raul Puri , Mostofa Patwary , Mohammad Shoeybi , Raghav Mani

Text embeddings have become an essential part of a variety of language applications. However, methods for interpreting, exploring and reversing embedding spaces are limited, reducing transparency and precluding potentially valuable…

Computation and Language · Computer Science 2026-01-27 Brian Ondov , Chia-Hsuan Chang , Yujia Zhou , Mauro Giuffrè , Hua Xu

Biomedical Named Entity Recognition (NER) is a challenging problem in biomedical information processing due to the widespread ambiguity of out of context terms and extensive lexical variations. Performance on bioNER benchmarks continues to…

Computation and Language · Computer Science 2019-08-19 Shreyas Sharma , Ron Daniel

Pre-trained text encoders such as BERT and its variants have recently achieved state-of-the-art performances on many NLP tasks. While being effective, these pre-training methods typically demand massive computation resources. To accelerate…

Computation and Language · Computer Science 2022-03-04 Jiaming Shen , Jialu Liu , Tianqi Liu , Cong Yu , Jiawei Han

Recent advances in natural language processing (NLP) owe their success to pre-training language models on large amounts of unstructured data. Still, there is an increasing effort to combine the unstructured nature of LMs with structured…

Computation and Language · Computer Science 2023-12-22 Juraj Vladika , Alexander Fichtl , Florian Matthes