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Clinical language models have achieved strong performance on downstream tasks by pretraining on domain specific corpora such as discharge summaries and medical notes. However, most approaches treat the electronic health record as a static…

Computation and Language · Computer Science 2025-04-28 Tatsunori Tanaka , Fi Zheng , Kai Sato , Zhifeng Li , Yuanyun Zhang , Shi Li

Multimodal Large Language Models have demonstrated powerful cross-modal understanding and reasoning capabilities in general domains. However, in the electromagnetic (EM) domain, they still face challenges such as data scarcity and…

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in…

Computation and Language · Computer Science 2023-06-19 Guangyu Wang , Guoxing Yang , Zongxin Du , Longjun Fan , Xiaohu Li

Recently, domain-specific PLMs have been proposed to boost the task performance of specific domains (e.g., biomedical and computer science) by continuing to pre-train general PLMs with domain-specific corpora. However, this Domain-Adaptive…

Computation and Language · Computer Science 2024-02-20 Zhongwei Wan , Yichun Yin , Wei Zhang , Jiaxin Shi , Lifeng Shang , Guangyong Chen , Xin Jiang , Qun Liu

Obtaining large-scale annotated data for NLP tasks in the scientific domain is challenging and expensive. We release SciBERT, a pretrained language model based on BERT (Devlin et al., 2018) to address the lack of high-quality, large-scale…

Computation and Language · Computer Science 2019-09-12 Iz Beltagy , Kyle Lo , Arman Cohan

Electronic health records (EHRs), digital collections of patient healthcare events and observations, are ubiquitous in medicine and critical to healthcare delivery, operations, and research. Despite this central role, EHRs are notoriously…

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for…

Motivation: A perennial challenge for biomedical researchers and clinical practitioners is to stay abreast with the rapid growth of publications and medical notes. Natural language processing (NLP) has emerged as a promising direction for…

Computation and Language · Computer Science 2021-12-16 Robert Tinn , Hao Cheng , Yu Gu , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

Images in the medical domain are fundamentally different from the general domain images. Consequently, it is infeasible to directly employ general domain Visual Question Answering (VQA) models for the medical domain. Additionally, medical…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Yash Khare , Viraj Bagal , Minesh Mathew , Adithi Devi , U Deva Priyakumar , CV Jawahar

In automatic speech recognition (ASR) rescoring, the hypothesis with the fewest errors should be selected from the n-best list using a language model (LM). However, LMs are usually trained to maximize the likelihood of correct word…

Computation and Language · Computer Science 2021-10-06 Hayato Futami , Hirofumi Inaguma , Masato Mimura , Shinsuke Sakai , Tatsuya Kawahara

Capturing sentence semantics plays a vital role in a range of text mining applications. Despite continuous efforts on the development of related datasets and models in the general domain, both datasets and models are limited in biomedical…

Computation and Language · Computer Science 2019-09-09 Qingyu Chen , Jingcheng Du , Sun Kim , W. John Wilbur , Zhiyong Lu

This paper presents Masked ELMo, a new RNN-based model for language model pre-training, evolved from the ELMo language model. Contrary to ELMo which only uses independent left-to-right and right-to-left contexts, Masked ELMo learns fully…

Computation and Language · Computer Science 2020-10-12 Gregory Senay , Emmanuelle Salin

We evaluate four state-of-the-art instruction-tuned large language models (LLMs) -- ChatGPT, Flan-T5 UL2, Tk-Instruct, and Alpaca -- on a set of 13 real-world clinical and biomedical natural language processing (NLP) tasks in English, such…

Computation and Language · Computer Science 2024-06-11 Yanis Labrak , Mickael Rouvier , Richard Dufour

While pre-trained language models (PTLMs) have achieved noticeable success on many NLP tasks, they still struggle for tasks that require event temporal reasoning, which is essential for event-centric applications. We present a continual…

Computation and Language · Computer Science 2021-09-20 Rujun Han , Xiang Ren , Nanyun Peng

Many NLP applications, such as biomedical data and technical support, have 10-100 million tokens of in-domain data and limited computational resources for learning from it. How should we train a language model in this scenario? Most…

Computation and Language · Computer Science 2020-10-01 Charles Welch , Rada Mihalcea , Jonathan K. Kummerfeld

This paper shines a light on the potential of definition-based semantic models for detecting idiomatic and semi-idiomatic multiword expressions (MWEs) in clinical terminology. Our study focuses on biomedical entities defined in the UMLS…

Computation and Language · Computer Science 2023-05-12 François Remy , Alfiya Khabibullina , Thomas Demeester

We explore the suitability of unsupervised representation learning methods on biomedical text -- BioBERT, SciBERT, and BioSentVec -- for biomedical question answering. To further improve unsupervised representations for biomedical QA, we…

Computation and Language · Computer Science 2020-09-29 Vaishnavi Kommaraju , Karthick Gunasekaran , Kun Li , Trapit Bansal , Andrew McCallum , Ivana Williams , Ana-Maria Istrate

Despite advances in machine learning (ML) and large language models (LLMs), rule-based natural language processing (NLP) systems remain active in clinical settings due to their interpretability and operational efficiency. However, their…

Computation and Language · Computer Science 2025-06-23 Jianlin Shi , Brian T. Bucher
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