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Despite the widespread success of self-supervised learning via masked language models (MLM), accurately capturing fine-grained semantic relationships in the biomedical domain remains a challenge. This is of paramount importance for…

Computation and Language · Computer Science 2021-04-08 Fangyu Liu , Ehsan Shareghi , Zaiqiao Meng , Marco Basaldella , Nigel Collier

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

Biomedical Question Answering aims to obtain an answer to the given question from the biomedical domain. Due to its high requirement of biomedical domain knowledge, it is difficult for the model to learn domain knowledge from limited…

Computation and Language · Computer Science 2022-06-29 Yuxuan Lu , Jingya Yan , Zhixuan Qi , Zhongzheng Ge , Yongping Du

Pre-training large language models on genomic sequences is a powerful approach for learning biologically meaningful representations. Masked language modeling (MLM) methods, such as DNABERT and Nucleotide Transformer (NT), achieve strong…

Genomics · Quantitative Biology 2025-08-20 Ke Ding , Brian Parker , Jiayu Wen

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen

The emergence of Pre-trained Language Models (PLMs) has achieved tremendous success in the field of Natural Language Processing (NLP) by learning universal representations on large corpora in a self-supervised manner. The pre-trained models…

Information Retrieval · Computer Science 2023-09-14 Peng Liu , Lemei Zhang , Jon Atle Gulla

The utilization of clinical reports for various secondary purposes, including health research and treatment monitoring, is crucial for enhancing patient care. Natural Language Processing (NLP) tools have emerged as valuable assets for…

Computation and Language · Computer Science 2023-06-14 Iker de la Iglesia , Aitziber Atutxa , Koldo Gojenola , Ander Barrena

Pre-training and fine-tuning have emerged as a promising paradigm across various natural language processing (NLP) tasks. The effectiveness of pretrained large language models (LLM) has witnessed further enhancement, holding potential for…

Computation and Language · Computer Science 2023-11-06 Guoxing Yang , Jianyu Shi , Zan Wang , Xiaohong Liu , Guangyu Wang

Biomedical named entity recognition (NER) is a fundamental task in text mining of medical documents and has many applications. Deep learning based approaches to this task have been gaining increasing attention in recent years as their…

Computation and Language · Computer Science 2018-08-16 Devendra Singh Sachan , Pengtao Xie , Mrinmaya Sachan , Eric P Xing

The success of pretrained word embeddings has motivated their use in the biomedical domain, with contextualized embeddings yielding remarkable results in several biomedical NLP tasks. However, there is a lack of research on quantifying…

Computation and Language · Computer Science 2021-07-27 Vladimir Araujo , Andrés Carvallo , Carlos Aspillaga , Camilo Thorne , Denis Parra

Named entity recognition (NER) is a widely applicable natural language processing task and building block of question answering, topic modeling, information retrieval, etc. In the medical domain, NER plays a crucial role by extracting…

Computation and Language · Computer Science 2020-11-13 Veysel Kocaman , David Talby

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

Pre-trained language models (LMs) have become ubiquitous in solving various natural language processing (NLP) tasks. There has been increasing interest in what knowledge these LMs contain and how we can extract that knowledge, treating LMs…

Computation and Language · Computer Science 2021-09-16 Mujeen Sung , Jinhyuk Lee , Sean Yi , Minji Jeon , Sungdong Kim , Jaewoo Kang

Masked language modeling (MLM) pre-training methods such as BERT corrupt the input by replacing some tokens with [MASK] and then train a model to reconstruct the original tokens. While they produce good results when transferred to…

Computation and Language · Computer Science 2020-03-25 Kevin Clark , Minh-Thang Luong , Quoc V. Le , Christopher D. Manning

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Computation and Language · Computer Science 2022-11-01 Sicen Liu , Xiaolong Wang , Yongshuai Hou , Ge Li , Hui Wang , Hui Xu , Yang Xiang , Buzhou Tang

Recently, the performance of Pre-trained Language Models (PLMs) has been significantly improved by injecting knowledge facts to enhance their abilities of language understanding. For medical domains, the background knowledge sources are…

Computation and Language · Computer Science 2021-08-23 Taolin Zhang , Zerui Cai , Chengyu Wang , Minghui Qiu , Bite Yang , Xiaofeng He

Fine-tuning Large Language Models (LLMs) is now a common approach for text classification in a wide range of applications. When labeled documents are scarce, active learning helps save annotation efforts but requires retraining of massive…

Machine Learning · Computer Science 2024-02-27 Artem Vysogorets , Achintya Gopal

Supervised models trained to predict properties from representations have been achieving high accuracy on a variety of tasks. For instance, the BERT family seems to work exceptionally well on the downstream task from NER tagging to the…

Computation and Language · Computer Science 2020-12-22 Tejas Vaidhya , Ayush Kaushal

In recent years, there has been substantial progress in using pretrained Language Models (LMs) on a range of tasks aimed at improving the understanding of biomedical texts. Nonetheless, existing biomedical LLMs show limited comprehension of…

Computation and Language · Computer Science 2025-09-10 Andrey Sakhovskiy , Elena Tutubalina

In recent years, major advancements in natural language processing (NLP) have been driven by the emergence of large language models (LLMs), which have significantly revolutionized research and development within the field. Building upon…

Computation and Language · Computer Science 2023-05-09 Hazal Türkmen , Oğuz Dikenelli , Cenk Eraslan , Mehmet Cem Çallı , Süha Süreyya Özbek
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