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In modern electronic medical records (EMR) much of the clinically important data - signs and symptoms, symptom severity, disease status, etc. - are not provided in structured data fields, but rather are encoded in clinician generated…

Computation and Language · Computer Science 2014-08-10 Son Doan , Mike Conway , Tu Minh Phuong , Lucila Ohno-Machado

Contextual word embedding models such as ELMo (Peters et al., 2018) and BERT (Devlin et al., 2018) have dramatically improved performance for many natural language processing (NLP) tasks in recent months. However, these models have been…

Computation and Language · Computer Science 2019-06-24 Emily Alsentzer , John R. Murphy , Willie Boag , Wei-Hung Weng , Di Jin , Tristan Naumann , Matthew B. A. McDermott

This work presents biomedical and clinical language models for Spanish by experimenting with different pretraining choices, such as masking at word and subword level, varying the vocabulary size and testing with domain data, looking for…

Domain-specific text embeddings are critical for clinical natural language processing, yet systematic comparisons across model architectures remain limited. This study evaluates ten transformer-based embedding models adapted for cardiology…

Computation and Language · Computer Science 2025-11-26 Richard J. Young , Alice M. Matthews

Natural language processing (NLP) tasks (text classification, named entity recognition, etc.) have seen revolutionary improvements over the last few years. This is due to language models such as BERT that achieve deep knowledge transfer by…

Computation and Language · Computer Science 2021-05-27 Lee Burke , Karl Pazdernik , Daniel Fortin , Benjamin Wilson , Rustam Goychayev , John Mattingly

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

Computation and Language · Computer Science 2023-08-21 Pavlova Vera , Mohammed Makhlouf

In this paper, we introduce ELECTRA-style tasks to cross-lingual language model pre-training. Specifically, we present two pre-training tasks, namely multilingual replaced token detection, and translation replaced token detection. Besides,…

Computation and Language · Computer Science 2022-04-20 Zewen Chi , Shaohan Huang , Li Dong , Shuming Ma , Bo Zheng , Saksham Singhal , Payal Bajaj , Xia Song , Xian-Ling Mao , Heyan Huang , Furu Wei

Most biomedical pretrained language models are monolingual and cannot handle the growing cross-lingual requirements. The scarcity of non-English domain corpora, not to mention parallel data, poses a significant hurdle in training…

Computation and Language · Computer Science 2023-11-21 Lei Geng , Xu Yan , Ziqiang Cao , Juntao Li , Wenjie Li , Sujian Li , Xinjie Zhou , Yang Yang , Jun Zhang

Large language models (LLMs) have revolutionized Natural Language Processing (NLP) by minimizing the need for complex feature engineering. However, the application of LLMs in specialized domains like biopharmaceuticals and chemistry remains…

Large language models (LLMs) have demonstrated dominating performance in many NLP tasks, especially on generative tasks. However, they often fall short in some information extraction tasks, particularly those requiring domain-specific…

Computation and Language · Computer Science 2023-09-22 Junyi Bian , Jiaxuan Zheng , Yuyi Zhang , Shanfeng Zhu

Domain adaptation of Pretrained Language Models (PTLMs) is typically achieved by unsupervised pretraining on target-domain text. While successful, this approach is expensive in terms of hardware, runtime and CO_2 emissions. Here, we propose…

Computation and Language · Computer Science 2020-06-30 Nina Poerner , Ulli Waltinger , Hinrich Schütze

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

The injection of domain-specific knowledge is crucial for adapting language models (LMs) to specialized fields such as biomedicine. While most current approaches rely on unstructured text corpora, this study explores two complementary…

Computation and Language · Computer Science 2026-04-21 Jaafer Klila , Sondes Bannour Souihi , Rahma Boujelben , Nasredine Semmar , Lamia Hadrich Belguith

Biomedical question-answering (QA) has gained increased attention for its capability to provide users with high-quality information from a vast scientific literature. Although an increasing number of biomedical QA datasets has been recently…

Computation and Language · Computer Science 2021-02-17 Gabriele Pergola , Elena Kochkina , Lin Gui , Maria Liakata , Yulan He

Recently, for few-shot or even zero-shot learning, the new paradigm "pre-train, prompt, and predict" has achieved remarkable achievements compared with the "pre-train, fine-tune" paradigm. After the success of prompt-based GPT-3, a series…

Computation and Language · Computer Science 2022-07-21 Shiwen Ni , Hung-Yu Kao

Over the recent years, the emergence of large language models (LLMs) has given rise to a proliferation of domain-specific models that are intended to reflect the particularities of linguistic context and content as a correlate of the…

Computation and Language · Computer Science 2024-02-20 Chris von Csefalvay

Pretrained language models have served as important backbones for natural language processing. Recently, in-domain pretraining has been shown to benefit various domain-specific downstream tasks. In the biomedical domain, natural language…

Computation and Language · Computer Science 2022-04-25 Hongyi Yuan , Zheng Yuan , Ruyi Gan , Jiaxing Zhang , Yutao Xie , Sheng Yu

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Prompt engineering significantly influences the reliability and clinical utility of Large Language Models (LLMs) in medical applications. Current optimization approaches inadequately address domain-specific medical knowledge and safety…

Computation and Language · Computer Science 2025-08-26 Yinda Chen , Yangfan He , Jing Yang , Dapeng Zhang , Zhenlong Yuan , Muhammad Attique Khan , Jamel Baili , Por Lip Yee

The recent success of question answering systems is largely attributed to pre-trained language models. However, as language models are mostly pre-trained on general domain corpora such as Wikipedia, they often have difficulty in…

Computation and Language · Computer Science 2019-09-19 Wonjin Yoon , Jinhyuk Lee , Donghyeon Kim , Minbyul Jeong , Jaewoo Kang