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Despite the broadband nature of thermal light sources, optical spectroscopy over multiple spectral bands simultaneously remains challenging. Here, we demonstrate a practical Fourier transform infrared spectrometer (FTIR) that achieves…

Controlling thermal emission is essential for various infrared spectroscopy applications. Metasurfaces can be utilized to control multiple degrees of freedom of thermal emission, enabling the compact thermal emission materials and devices.…

Optics · Physics 2023-11-14 Qiongqiong Chu , Fengyuan Zhang , Ye Zhang , Shining Zhu , Hui Liu

Black phosphorus stands out from the family of two-dimensional materials as a semiconductor with a direct, layer-dependent bandgap in energy corresponding to the spectral range from the visible to the mid-infrared (mid-IR), as well as many…

Optics · Physics 2017-10-10 Ruoming Peng , Kaveh Khaliji , Nathan Youngblood , Roberto Grassi , Tony Low , Mo Li

Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz

Sensing with undetected photons has enabled new, unconventional approaches to Fourier transform infrared (FTIR) spectroscopy. Leveraging properties of non-degenerated entangled photon pairs, mid-IR information can be accessed in the near-IR…

Minfrared spectroscopic imaging (MIRSI) is an emerging class of label-free, biochemically quantitative technologies targeting digital histopathology. Conventional histopathology relies on chemical stains that alter tissue color. This…

Image and Video Processing · Electrical Eng. & Systems 2022-07-26 Mahsa Lotfollahi , Nguyen Tran , Sebastian Berisha , Chalapathi Gajjela , Zhu Han , David Mayerich , Rohith Reddy

To measure low-temperature thermal fields, we have developed a single-element cooled thermal imaging camera for a spectral range of 8{\div}14 {\mu}m with an internal shutter for radiometric calibration. To improve the accuracy of measuring…

Instrumentation and Detectors · Physics 2024-08-30 E. Gordiyenko , Yu. Fomenko , G. Shustakova , G. Kovalov , S. Shevchenko

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique in biomedical research that uses the fluorophore decay rate to provide additional contrast in fluorescence microscopy. However, at present, the calculation, analysis,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Cara Ravasio , Scott S. Howard

We present an experimental setup and methodology designed to facilitate high-precision thermal measurements required for infrared medical tomography. The approach which is best suited for the study of specialized hardware phantoms comprises…

Medical Physics · Physics 2026-04-08 Anna Frixou , Efstathios Stiliaris , Costas N. Papanicolas

Light in the mid-infrared (mid-IR) spans wavelengths from 3-8 $\mu$m and is important to many applications such as gas sensing and thermal imaging. Due to materials challenges, there is currently a lack of mid-IR reconfigurable optical…

Modern imaging systems can be enhanced in efficiency, compactness, and application through introduction of multilayer nanopatterned structures for manipulation of light based on its fundamental properties. High transmission efficiency…

Fluorescence fluctuation spectroscopy is applied to study molecules, passing through a small observation volume, usually subjected to diffusive or convective motion in liquid phase. We suggest that such a technique could be used to measure…

Mid-infrared spectroscopy, an important and widespread technique for sensing molecules, has encountered barriers stemming from sources either limited in tuning range or excessively bulky for practical field use. We present a compact,…

Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell…

Outlined here is a technique for sub-wavelength infrared surface imaging performed using a phase matched optical parametric oscillator laser and an atomic force microscope as the detection mechanism. The technique uses a novel surface…

Hyperspectral imaging in the mid-infrared (MIR) spectral range provides unique molecular specificity by probing fundamental vibrational modes of molecular bonds, making it highly valuable for biomedical and biochemical applications.…

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

We investigate quantum spectroscopy with undetected photons for protein detection in the mid-infrared spectral region. Classical Fourier-transform infrared spectroscopy of protein samples (bovine serum albumin and N-terminal pro-brain…

FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM),…

Quantitative Methods · Quantitative Biology 2017-01-09 Bryan Kaye , Peter J. Foster , Tae Yeon Yoo , Daniel J. Needleman

A fundamental issue that limits the efficiency of many photoelectrochemical systems is that the photon absorption length is typically much longer than the electron diffusion length. Various photon management schemes have been developed to…