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This paper proposes a non-computational method of counteracting the effect of image degradation introduced by the diffraction phenomenon in lensless microscopy. All the optical images (whether focused by lenses or not) are diffraction…

Optics · Physics 2021-04-08 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, offer substantial advantages for in vivo imaging, owing to their deep tissue penetration and minimal background autofluorescence. Nanoparticles incorporating…

Medical Physics · Physics 2024-11-07 Michael Adeniyi

In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The…

Optics · Physics 2021-01-07 Antoine Boniface , Jonathan Dong , Sylvain Gigan

A near-field microwave imaging system attempts to reveal the presence of an object and/or an electrical property distribution by measuring the scattered field from many positions surrounding the object. Over the past few decades, both the…

Medical Physics · Physics 2019-09-26 Wenyi Shao

Recovering molecular information remains a grand challenge in the widely used holographic and computational imaging technologies. To address this challenge, we developed a computational mid-infrared photothermal microscope, termed…

Far-field chemical microscopy providing molecular electronic or vibrational fingerprint information opens a new window for the study of three-dimensional biological, material, and chemical systems. Chemical microscopy provides a…

Optics · Physics 2023-06-06 Mingwei Tang , Yubing Han , Danchen Jia , Qing Yang , Ji-Xin Cheng

Spectral imaging in the mid-infrared (MIR) range provides simultaneous morphological and chemical information of a wide variety of samples. However, current MIR technologies struggle to produce high-definition images over a broad spectral…

Fourier transform (FT) spectroscopy is a versatile technique for studying the infrared (IR) optical response of solid-, liquid-, and gas-phase samples. In standard FT-IR spectrometers, a light beam passing through a Michelson interferometer…

Applied Physics · Physics 2021-03-12 Takashi Kuroda , Siti Chalimah , Yuanzhao Yao , Naoki Ikeda , Yoshimasa Sugimoto , Kazuaki Sakoda

Decades ago, the losses of glasses in the near infrared (near-IR) were investigated in views of developments for optical telecommunications. Today, properties in the mid-infrared (mid-IR) are of interest for molecular spectroscopy…

Optics · Physics 2016-12-07 C. Lecaplain , C. Javerzac-Galy , M. L. Gorodetsky , T. J. Kippenberg

Black phosphorus is a layered semiconductor that is intensely researched in view of applications in optoelectronics. In this Letter, we investigate a multi-layer black phosphorus photo-detector that is capable of acquiring high-contrast…

Materials Science · Physics 2016-01-12 Michael Engel , Mathias Steiner , Phaedon Avouris

Label-free vibrational microscopy provides chemically specific access to cellular structure, yet quantitative volumetric chemical dynamics in living cells remain largely inaccessible, particularly on subsecond timescales relevant to…

Multi-mode fiber (MMF) endoscopes are a new type of endoscope that use only a single optical fiber to transmit images, achieving much higher spatial resolution for a given diameter than commercial fiber bundle endoscopes. However, a…

Optics · Physics 2018-05-22 Ruo Yu Gu , Elaine Chou , Cory Rewcastle , Ofer Levi , Joseph M. Kahn

Infrared (IR) spectroscopy, a well established tool for chemical analysis of diverse materials, has significant potential in biomedical applications. While the spatial resolution of traditional IR spectroscopy is limited by the wavelength…

Single-photon avalanche diode (SPAD) arrays have transformed optical imaging by enabling photon-counting sensitivity, picosecond resolution, and high frame-rate operation. These capabilities, however, have remained confined to the visible…

Spectroscopy and imaging in the mid-infrared (2.5 $\mu$m $\sim$ $\lambda$ $\sim$ 25 $\mu$m) is bedevilled by the presence of a strong 300 K thermal background at room temperature that makes IR detectors decades noisier than can be readily…

Quantum Physics · Physics 2023-11-28 Yue Ma , Nathan Gemmell , Emma Pearce , Rupert Oulton , Chris Phillips

Photothermal spectroscopy and microscopy provides a route to measure the spectral and spatial properties of individual nanoscopic absorbers, independent from scattering, extinction, and emission. The approach relies upon use of two light…

Optics · Physics 2021-04-12 Harrison J. Goldwyn , Stephan Link , David J. Masiello

The U. C. Berkeley Infrared Spatial Interferometer has been outfitted with a filterbank system to allow interferometric observations of mid-infrared spectral lines with very high spectral resolution (R ~ 10^5). This paper describes the…

Astrophysics · Physics 2009-10-31 J. D. Monnier , W. Fitelson , W. C. Danchi , C. H. Townes

Besides being the foundational material for microelectronics, in optics, crystalline silicon has long been used for making infrared lenses and mirrors. More recently, silicon has become the key material to achieve large-scale integration of…

Optics · Physics 2014-03-07 Yu Chen , Hongtao Lin , Juejun Hu , Mo Li

Hyperspectroscopy is a new method of surface image taking, providing simultaneously high position and spectral resolutions which allow one to make some conclusions about chemical compositions of the surfaces. We are now studying…

Instrumentation and Detectors · Physics 2016-11-18 I. Rodionov , J-M. Bidault , I. Crotty , P. Fonte , F. Galy , V. Peskov , O. Zanette