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Coronary angioplasty with stent implantation is the most frequently used interventional treatment for coronary artery disease. However, reocclusion within the stent, referred to as in-stent restenosis, occurs in up to 10% of lesions. It is…

Computational Engineering, Finance, and Science · Computer Science 2025-02-19 Janina C. Datz , Ivo Steinbrecher , Christoph Meier , Nora Hagmeyer , Leif-Christopher Engel , Alexander Popp , Martin R. Pfaller , Heribert Schunkert , Wolfgang A. Wall

Blood transfusion is a frequently performed medical procedure in surgical and nonsurgical contexts. Although it is frequently necessary or even life-saving, it has been identified as one of the most overused procedures in hospitals.…

Human-Computer Interaction · Computer Science 2022-04-12 Haihan Lin , Ryan A. Metcalf , Jack Wilburn , Alexander Lex

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

Tissues and Organs · Quantitative Biology 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Whilst grading neurovascular abnormalities is critical for prompt surgical repair, no statistical markers are currently available for predicting the risk of adverse events, such as stroke, and the overall resilience of a network to vascular…

Quantitative Methods · Quantitative Biology 2019-10-30 Stefano Moriconi , Rafael Rehwald , Maria A. Zuluaga , H. Rolf Jäger , Parashkev Nachev , Sébastien Ourselin , M. Jorge Cardoso

Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid…

Medical Physics · Physics 2017-06-05 Ruchika Bhatia , Sharda Vashisth , Renu Saini

The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red…

Fluid Dynamics · Physics 2008-10-14 Amir H. G. Isfahani , Hong Zhao , Jonathan B. Freund

Coronary stenosis is a major risk factor for ischemic heart events leading to increased mortality, and medical treatments for this condition require meticulous, labor-intensive analysis. Coronary angiography provides critical visual cues…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Sumin Seo , In Kyu Lee , Hyun-Woo Kim , Jaesik Min , Chung-Hwan Jung

Brain stroke is a leading cause of mortality and long-term disability worldwide, underscoring the need for precise and rapid prediction techniques. Computed Tomography (CT) scan is considered one of the most effective methods for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Md. Sabbir Hossen , Eshat Ahmed Shuvo , Shibbir Ahmed Arif , Pabon Shaha , Anichur Rahman , Md. Saiduzzaman , Fahmid Al Farid , Hezerul Abdul Karim , Abu Saleh Musa Miah

Blood clots, consisting of red blood cells (RBCs) entrapped within a fibrin network, can cause life-threatening conditions such as stroke and heart attack. The recently developed milli-spinner thrombectomy device presents a promising…

Biological Physics · Physics 2025-05-09 Yilong Changa , Guansheng Li , Jay Sim , George Em Karniadakis , Ruike Renee Zhao

Blood exhibits a heterogeneous nature of hematocrit, velocity, and effective viscosity in microcapillaries. Microvascular bifurcations have a significant influence on the distribution of the blood cells and blood flow behavior. This paper…

Biological Physics · Physics 2016-02-24 Tong Wang , Uwitije Rongin , Zhongwen Xing

Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over…

Biological Physics · Physics 2025-02-18 Shobhit Das , Shilpi Pandey , Oliver Hayden

Currently, it is challenging to investigate aneurismal hemodynamics based on current in-vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we…

Fluid Dynamics · Physics 2024-10-17 Thien-Tam Nguyen , Davina Kasperski , Phat Kim Huynh , Trung Quoc Le , Trung Bao Le

An arteriovenous fistula, created by artificially connecting segments of a patient's vasculature, is the preferred way to gain access to the bloodstream for kidney dialysis. The increasing power and availability of supercomputing…

Medical Physics · Physics 2021-06-14 J. W. S. McCullough , P. V. Coveney

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche

Stroke remains a leading cause of global morbidity and mortality, imposing a heavy socioeconomic burden. Advances in endovascular reperfusion therapy and CT and MR imaging for treatment guidance have significantly improved patient outcomes.…

A brain stroke occurs when blood flow to a part of the brain is disrupted, leading to cell death. Traditional stroke diagnosis methods, such as CT scans and MRIs, are costly and time-consuming. This study proposes a weighted voting ensemble…

Machine Learning · Computer Science 2025-04-22 Yao Zhiwan , Reza Zarrab , Jean Dubois

Magnetic resonance imaging (MRI) is a central modality for stroke imaging. It is used upon patient admission to make treatment decisions such as selecting patients for intravenous thrombolysis or endovascular therapy. MRI is later used in…

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

In this paper, we propose a reservoir computing-based and directed graph analysis pipeline. The goal of this pipeline is to define an efficient brain representation for connectivity in stroke data derived from magnetic resonance imaging.…

Machine Learning · Computer Science 2025-01-28 Wojciech Ciezobka , Joan Falco-Roget , Cemal Koba , Alessandro Crimi

Regularized optimal mass transport (rOMT) problem adds a diffusion term to the continuity equation in the original dynamic formulation of the optimal mass transport (OMT) problem proposed by Benamou and Brenier. We show that the rOMT model…

Numerical Analysis · Mathematics 2022-01-20 Xinan Chen , Anh Phong Tran , Rena Elkin , Helene Benveniste , Allen R. Tannenbaum