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We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…

Medical Physics · Physics 2019-07-29 Olivier Adjoua , Stéphanie Pitre-Champagnat , Didier Lucor

We focus on reducing the computational costs associated with the hydrodynamic stability of solutions of the incompressible Navier-Stokes equations for a Newtonian and viscous fluid in contraction-expansion channels. In particular, we are…

Numerical Analysis · Mathematics 2017-09-01 Giuseppe Pitton , Annalisa Quaini , Gianluigi Rozza

Volume visualization is a method that displays three-dimensional (3D) data in two-dimensional (2D) space. Using 3D datasets instead of 2D traditional images improves the visualization of anatomical structures, and volume visualization helps…

Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors…

Tissues and Organs · Quantitative Biology 2022-08-26 Alexander D. Kaiser , Rohan Shad , Nicole Schiavone , William Hiesinger , Alison L. Marsden

Background and Objective: This study aims to evaluate the dynamic effect of non-Newtonian cerebral arterial circulation on electrical conductivity distribution (ECD) in a realistic multi-compartment head model. It addresses the importance…

Analysis of PDEs · Mathematics 2023-05-31 Maryam Samavaki , Arash Zarrin Nia , Santtu Söderholm , Sampsa Pursiainen

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

Cerebral hemodynamics is fundamentally regulated by the Circle of Willis (CoW), which redistributes flow through communicating arteries to stabilize perfusion under anatomical variations and vascular stenosis. In this study, we develop a…

Medical Physics · Physics 2025-12-22 Jiawei Liu , Atsushi Kanoke , Hidenori Endo , Kuniyasu Niizuma , Hiroshi Suito

Computational fluid dynamics is intensively used to deepen the understanding of aneurysm growth and rupture in the attempt to support physicians during therapy planning. Numerous studies have assumed fully-rigid vessel walls in their…

Fluid Dynamics · Physics 2023-08-17 Aurèle Goetz , Pablo Jeken Rico , Yves Chau , Jacques Sédat , Aurélien Larcher , Elie Hachem

The link between atherosclerosis and blood flow-induced haemodynamic luminal shear stresses is well established. However, this understanding has not been translated into clinical practice because of the interdependent effects of the complex…

Medical Physics · Physics 2023-12-04 Mingzi Zhang , Ramtin Gharleghi , Chi Shen , Susann Beier

Among cardiovascular diseases, atherosclerosis is a primary cause of stenosis, involving the accumulation of plaques in the inner lining of an artery. Inspired by drug delivery applications, the proposed study aims to examine the numerical…

Fluid Dynamics · Physics 2025-04-17 Nimra Muqaddass , Alessandra Jannelli , Francesco Oliveri

Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from desktops…

In the last years, medical computer simulation has seen a great growth in several scientific branches, from modelling to numerical methods, going through computer science. The main goals of this incipient discipline are testing hypotheses…

Fluid Dynamics · Physics 2017-10-20 Cristóbal Rodero Gómez

Cardio-cerebrovascular diseases are the leading causes of mortality worldwide, whose accurate blood vessel segmentation is significant for both scientific research and clinical usage. However, segmenting cardio-cerebrovascular structures…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Nazik Elsayed , Yousuf Babiker M. Osman , Cheng Li , Jiong Zhang , Shanshan Wang

The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…

Image and Video Processing · Electrical Eng. & Systems 2021-02-01 Chengyang Zhou , Thao Vy Dinh , Heyi Kong , Jonathan Yap , Khung Keong Yeo , Hwee Kuan Lee , Kaicheng Liang

Simulating the interaction of fluids with immersed moving solids is playing an important role for gaining a better quantitative understanding of how fluid dynamics is altered by the presence of obstacles and which forces are exerted on the…

The study is looking into the potential of using computational fluid dynamics (CFD) as a tool for predicting the outcome of surgery for alleviation of obstructive sleep apnea syndrome (OSAS). From pre- and post-operative computed tomography…

Dense flow visualization is a popular visualization paradigm. Traditionally, the various models and methods in this area use a continuous formulation, resting upon the solid foundation of functional analysis. In this work, we examine a…

Graphics · Computer Science 2020-07-06 Daniel Preuß , Tino Weinkauf , Jens Krüger

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Stent intervention is a recommended therapy to reduce the pressure gradient and restore blood flow for patients with coarctation of the aorta (CoA). In this work, we developed a framework for personalized stent intervention in CoA using in…

Medical Physics · Physics 2022-10-12 Dandan Ma , Yong Wang , Mueed Azhar , Ansgar Adler , Michael Steinmetz , Martin Uecker

We present a method for learning neural representations of flow maps from time-varying vector field data. The flow map is pervasive within the area of flow visualization, as it is foundational to numerous visualization techniques, e.g.…

Graphics · Computer Science 2023-03-28 Saroj Sahoo , Matthew Berger